{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:01:11Z","timestamp":1761919271653},"reference-count":24,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pract Neurol"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:p>Neuromyelitis optica (NMO), also known as Devic\u2019s disease, is an emerging clinical and pathological entity originally thought to be a variant of multiple sclerosis. Characterised by episodes of demyelination confined to the optic nerve and spinal cord, the discovery in such patients of antibodies to the aquaporin-4 channel has been largely responsible for defining the phenotype to date. Recently it has become clear that there is a borderland where there are patients with optic neuritis-only and myelitis-only forms of the disease, and these may be seronegative in the early phase. We describe two cases of optic neuritis-only NMO, and explore the current understanding of the diagnosis and spectrum of NMO disorders.<\/jats:p>","DOI":"10.1136\/jnnp.2009.193888","type":"journal-article","created":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T05:18:03Z","timestamp":1258521483000},"page":"335-340","source":"Crossref","is-referenced-by-count":5,"title":["The borderland of neuromyelitis optica"],"prefix":"10.1136","volume":"9","author":[{"given":"Lucy A E","family":"Matthews","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahd","family":"Baig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Palace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin R","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2009,11,17]]},"reference":[{"key":"2024052910390685000_9.6.335.1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.5.1107"},{"key":"2024052910390685000_9.6.335.2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/39.2.215"},{"key":"2024052910390685000_9.6.335.3","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf151"},{"key":"2024052910390685000_9.6.335.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17551-X"},{"key":"2024052910390685000_9.6.335.5","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050304"},{"key":"2024052910390685000_9.6.335.6","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000216139.44259.74"},{"key":"2024052910390685000_9.6.335.7","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg045"},{"key":"2024052910390685000_9.6.335.8","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.7.964"},{"key":"2024052910390685000_9.6.335.9","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.3.390"},{"key":"2024052910390685000_9.6.335.10","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000343001.36493.ae"},{"key":"2024052910390685000_9.6.335.11","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-1901hyp"},{"key":"2024052910390685000_9.6.335.12","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.10.1398"},{"key":"2024052910390685000_9.6.335.13","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000303817.82134.da"},{"key":"2024052910390685000_9.6.335.14","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1212\/01.WNL.0000049912.02954.2C","article-title":"Neuromyelitis optica: clinical predictors of a relapsing course and survival.","volume":"60","author":"Wingerchuk","year":"2003","journal-title":"Neurology"},{"key":"2024052910390685000_9.6.335.15","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.65.7.913"},{"key":"2024052910390685000_9.6.335.16","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.9.1401"},{"key":"2024052910390685000_9.6.335.17","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000313375.20123.25"},{"key":"2024052910390685000_9.6.335.18","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn240"},{"key":"2024052910390685000_9.6.335.19","doi-asserted-by":"publisher","DOI":"10.1159\/000064490"},{"key":"2024052910390685000_9.6.335.20","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-007-0730-5"},{"key":"2024052910390685000_9.6.335.21","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-005-0010-6"},{"key":"2024052910390685000_9.6.335.22","doi-asserted-by":"publisher","DOI":"10.1177\/1352458506070732"},{"key":"2024052910390685000_9.6.335.23","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.65.11.noc80069"},{"key":"2024052910390685000_9.6.335.24","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1136\/jnnp.74.10.1443","article-title":"Sir Thomas Clifford Allbutt.","volume":"74","author":"Pearce","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.2009.193888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T17:39:15Z","timestamp":1717004355000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/jnnp.2009.193888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,17]]},"references-count":24,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2009,11,17]]},"published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1136\/jnnp.2009.193888"],"URL":"https:\/\/doi.org\/10.1136\/jnnp.2009.193888","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,17]]}}}