{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T07:48:44Z","timestamp":1773301724859,"version":"3.50.1"},"reference-count":24,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"published-print":{"date-parts":[[1966,10,1]]},"DOI":"10.1136\/jnnp.29.5.446","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T20:53:49Z","timestamp":1226350429000},"page":"446-450","source":"Crossref","is-referenced-by-count":35,"title":["Cerebral oedema and the water content of normal white matter."],"prefix":"10.1136","volume":"29","author":[{"given":"M","family":"Adachi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Feigin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00005072-196307000-00003","article-title":"Fine structure and electrolyte analyses of cerebral edema induced by alkyl tin intoxication","volume":"22","author":"Aleu, F.P.; Katzman, R.; Terry, R.D.","year":"1963","unstructured":"Aleu, F. P., Katzman, R., and Terry, R. D. (1963). Fine structure and electrolyte analyses of cerebral edema induced by alkyl tin intoxication. J. Neuropath. exp. Neurol., 22, 403-413.","journal-title":"J. Neuropath. exp. Neurol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0014-4827(57)90148-9","article-title":"Volume changes of tissues in physiological fluids during fixation in osmium tetroxide or formaldehyde and during subsequent treatment","volume":"12","author":"Bahr, G.F.; Bloom, G.; Friberg, U.","year":"1957","unstructured":"Bahr, G. F., Bloom, G., and Friberg, U. (1957). Volume changes of tissues in physiological fluids during fixation in osmium tetroxide or formaldehyde and during subsequent treatment. Exp. Cell Res., 12, 342-355.","journal-title":"Exp. Cell Res"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/00005072-196210000-00006","article-title":"Experimental cerebral edema produced by focal freezing. I. An anatomic study utilizing vital dye techniques","volume":"21","author":"Clasen, R.A.; Cooke, P.M.; Pandolfi, S.; Boyd, D.; Raimondi, A.J.","year":"1962","unstructured":"Clasen, R. A., Cooke, P. M., Pandolfi, S., Boyd, D., and Raimondi, A. J. (1962). Experimental cerebral edema produced by focal freezing. I. An anatomic study utilizing vital dye techniques. J. Neuropath. exp. Neurol., 21, 579-596.","journal-title":"J. Neuropath. exp. Neurol"},{"key":"ref_4","article-title":"The course and sequellae of brain edema. To be published as part of the reports of the Workshop on Brain Edema of the Problem Commission on Neuropathology of the World Federation of Neurology, September 11-13","author":"Feigin, I.","year":"1965","unstructured":"Feigin, I., (1965). The course and sequellae of brain edema. To be published as part of the reports of the Workshop on Brain Edema of the Problem Commission on Neuropathology of the World Federation of Neurology, September 11-13."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"\"151","DOI":"10.1001\/archneur.1962.00450200065006","article-title":"Neuropathological observations on cerebral edema: The acute phase","volume":"6","author":"Feigin, I.; Popoff, N.","year":"1962","unstructured":"Feigin, I., and Popoff, N. (1962). Neuropathological observations on cerebral edema: The acute phase. Arch. Neurol. (Chic.), 6, 151-160. - - (1963). Neuropathological changes late in cerebral edema: The relationship to trauma, hypertensive disease and Binswanger's encephalopathy. J. Neuropath. exp. Neurol., 22, 500-511.","journal-title":"Arch. Neurol. (Chic.); Neuropathological changes late in cerebral edema: The relationship to trauma, hypertensive disease and Binswanger's encephalopathy"},{"key":"ref_6","first-page":"323","article-title":"Beitrag zur technischen Bearbeitung des Centralnervensystems","volume":"13","author":"Flatau, E.","year":"1897","unstructured":"Flatau, E. (1897). Beitrag zur technischen Bearbeitung des Centralnervensystems. Anat. Anz., 13, 323-329.","journal-title":"Anat. Anz"},{"key":"ref_7","first-page":"67","volume-title":"Chemical composition of the mammalian nervous system. In Metabolism of the Nervous System","author":"Folch-Pi, J.; LeBaron, F.N.","year":"1957","unstructured":"Folch-Pi, J., and LeBaron, F. N. (1957). Chemical composition of the mammalian nervous system. In Metabolism of the Nervous System, pp. 67-71, edited by D. Richter. Pergamon Press, New York."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1212\/WNL.9.6.412","article-title":"Function of Astroglia in the Water-Ion Metabolism of the","volume":"9","author":"Gershenfeld, H.M.; Wald, F.; Zadunaisky, J.A.; de Robertis, E.P.D.","year":"1959","unstructured":"Gershenfeld, H. M., Wald, F., Zadunaisky, J. A., and de Robertis, E. P. D. (1959). Function of Astroglia in the Water-Ion Metabolism of the Central Nervous System. Neurology (Minneap.), 9, 412-425.","journal-title":"Central Nervous System. Neurology (Minneap.)"},{"key":"ref_9","first-page":"455","article-title":"Ultrastructure of inflammation with edema in the rat brain","volume":"42","author":"Gonatas, N.K.; Zimmerman, H.M.; Levine, S.","year":"1963","unstructured":"Gonatas, N. K., Zimmerman, H. M., and Levine, S. (1963). Ultrastructure of inflammation with edema in the rat brain. Amer. J. Path., 42, 455-469.","journal-title":"Amer. J. Path"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/brain\/62.2.129","article-title":"The histology of cerebral oedema associated with intracranial tumours (with special reference to changes in the nerve fibres of the centrum ovale)","volume":"62","author":"Greenfield, J.G.","year":"1939","unstructured":"Greenfield, J. G. (1939). The histology of cerebral oedema associated with intracranial tumours (with special reference to changes in the nerve fibres of the centrum ovale). Brain, 62, 129-152.","journal-title":"Brain"},{"key":"ref_11","first-page":"168","article-title":"Untersuchungen uber die Wirkurg von Hartungsflussigkeiten auf tierische Gewebe","volume":"49","author":"Gross, W.; Lohaus, H.","year":"1932","unstructured":"Gross, W., and Lohaus, H. (1932). Untersuchungen uber die Wirkurg von Hartungsflussigkeiten auf tierische Gewebe. Z. wiss. Mikroskop., 49, 168-190.","journal-title":"Z. wiss. Mikroskop"},{"key":"ref_12","first-page":"245","article-title":"Brains and brain preservatives. Part I. Physical changes in human and other brains collected under different conditions and preserved in various formalin preparations","volume":"30","author":"Hrdlieka, A.","year":"1906","unstructured":"Hrdlieka, A. (1906). Brains and brain preservatives. Part I. Physical changes in human and other brains collected under different conditions and preserved in various formalin preparations. Proc. U.S. nat. Mus., 30, 245-276.","journal-title":"Proc. U. S. nat. Mus"},{"key":"ref_13","first-page":"178","article-title":"Zur Kenntnis der Gewichtsund Volumen-veranderungen bei Formalinfixation von Gehirngewebe und der Einwirkung von NaCl-Zusatz darauf","volume":"46","author":"Lagerlof, H.; Torgersruud, T.","year":"1934","unstructured":"Lagerlof, H., and Torgersruud, T. (1934). Zur Kenntnis der Gewichtsund Volumen-veranderungen bei Formalinfixation von Gehirngewebe und der Einwirkung von NaCl-Zusatz darauf. J. Psychol. Neurol. (Lpz.), 46, 178-188.","journal-title":"J. Psychol. Neurol. (Lpz.)"},{"key":"ref_14","first-page":"150","article-title":"The ulstrastructure of human cerebral edema","volume":"24","author":"Long, D.M.; Hartmann, J.F.","year":"1965","unstructured":"Long, D. M., and Hartmann, J. F. (1965). The ulstrastructure of human cerebral edema. J. Neuropath. exp. Neurol., 24, 150-151.","journal-title":"J. Neuropath. exp. Neurol"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3171\/jns.1960.17.3.0439","article-title":"Electron microscopy of the brain in experimental edema","volume":"17","author":"Luse, S.A.; Harris, B.","year":"1960","unstructured":"Luse, S. A., and Harris, B. (1960). Electron microscopy of the brain in experimental edema. J. Neurosurg., 17, 439-446.","journal-title":"J. Neurosurg"},{"key":"ref_16","first-page":"7","article-title":"Yearbook of Neurology, Psychiatry and Neurosurgery","author":"Mackay, R.P.","year":"1962","unstructured":"Mackay, R. P. (1962-63). Yearbook of Neurology, Psychiatry and Neurosurgery, p. 7, Year Book Medical Publishers, Chicago."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/00005072-194310000-00003","article-title":"Histopathologic changes of the brain caused by intracranial tumors (so-called edema or swelling of the brain)","volume":"2","author":"Perret, G.E.; Kernohan, J.W.","year":"1943","unstructured":"Perret, G. E., and Kernohan, J. W. (1943). Histopathologic changes of the brain caused by intracranial tumors (so-called edema or swelling of the brain). J. Neuropath. exp. Neurol., 2, 341-352.","journal-title":"J. Neuropath. exp. Neurol"},{"key":"ref_18","first-page":"177","article-title":"Studies of cerebral edema. III. Alterations in the white matter: an electron microscopic study using Ferritin as a labelling compound","volume":"2","author":"Raimondi, A.J.; Evans, J.P.; Mullan, S.","year":"1962","unstructured":"Raimondi, A. J., Evans, J. P., and Mullan, S. (1962). Studies of cerebral edema. III. Alterations in the white matter: an electron microscopic study using Ferritin as a labelling compound. Acta neuropath. (Berl.), 2, 177-197.","journal-title":"Acta neuropath. (Berl.)"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3171\/jns.1947.4.3.0255","article-title":"Cerebral swelling: histopathology, classification and clinical significance of brain edema","volume":"4","author":"Scheinker, I.M.","year":"1947","unstructured":"Scheinker, I. M. (1947). Cerebral swelling: histopathology, classification and clinical significance of brain edema. J. Neurosurg., 4, 255-275.","journal-title":"J. Neurosurg"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/brain\/62.4.426","article-title":"A biochemical study of cerebral tissue, and of the changes in cerebral oedema","volume":"62","author":"Stewart-Wallace, A.M.","year":"1939","unstructured":"Stewart-Wallace, A. M. (1939). A biochemical study of cerebral tissue, and of the changes in cerebral oedema. Brain, 62, 426-438.","journal-title":"Brain"},{"key":"ref_21","first-page":"1135","article-title":"The fine structure ofcerebral fluid accumulation. I. Swelling secondary to cold injury","volume":"35","author":"Torack, R.M.; Terry, R.D.; Zimmerman, H.M.","year":"1959","unstructured":"Torack, R. M., Terry, R. D., and Zimmerman, H. M. (1959). The fine structure ofcerebral fluid accumulation. I. Swelling secondary to cold injury. Amer. J. Path., 35, 1135-1147.","journal-title":"Amer. J. Path"},{"key":"ref_22","article-title":"The fine structure of cerebral fluid accumulation: H. Swelling produced by triethyl tin poisoning and it, comparison with that in the human brain","unstructured":"-, *-, - (1960). The fine structure of cerebral fluid accumulation: H. Swelling produced by triethyl tin poisoning and it, comparison with that in the human brain. Amer. J. Path.","journal-title":"Amer. J. Path"},{"key":"ref_23","first-page":"831","article-title":"Some contributions of electron microscopy to problems in pathology. The Twenty-Fourth Middleton Goldsmith Lecture","volume":"40","author":"Zimmerman, H.M.","year":"1964","unstructured":"Zimmerman, H. M. (1964). Some contributions of electron microscopy to problems in pathology. The Twenty-Fourth Middleton Goldsmith Lecture. Bull. N.Y. Acad. Med., 40, 831-862.","journal-title":"Bull. N. Y. Acad. Med"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02598063","article-title":"Hirnodem und Hirnschwellung","volume":"310","author":"Zulch, K.J.","year":"1943","unstructured":"Zulch, K. J. (1943). Hirnodem und Hirnschwellung. Virchows Arch. path. Anat., 310, 1-58.","journal-title":"Virchows Arch. path. Anat"}],"container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.29.5.446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T02:20:07Z","timestamp":1601086807000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.29.5.446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,10,1]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1966,10,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.29.5.446","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1966,10,1]]}}}