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In time, as the respiratory hypoexcitability becomes more pronounced, conditions are created which lead to a worsening of the syndrome; alveolar hypoventilation and CO2 retention extend to the waking hours, while the abnormalities that usually accompany conditions of chronic alveolar hypoventilation make their appearance -that is, polyglobulia, right ventricular hypertrophy, and right heart failure","year":"1961","unstructured":"water swimmers (Goff and Bartlett, 1957; Billow, K., and Ingvar, D. H. (1961). Respiration and state Auchincloss and Gilbert, 1959). 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