{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:54:47Z","timestamp":1760982887377},"reference-count":19,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"published-print":{"date-parts":[[1973,8,1]]},"DOI":"10.1136\/jnnp.36.4.618","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T21:02:42Z","timestamp":1226350962000},"page":"618-624","source":"Crossref","is-referenced-by-count":45,"title":["Effect of the beta adrenergic blocking agent propranolol on essential tremor"],"prefix":"10.1136","volume":"36","author":[{"given":"M. H.","family":"Morgan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. L.","family":"Hewer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"154","article-title":"to peripheral blockage of beta adrenergic receptors. It has been suggested that the site","volume":"2","author":"of; Barcroft, H.; Peterson, E.; Schwab, R.S.","year":"1952","unstructured":"to peripheral blockage of beta adrenergic receptors. It has been suggested that the site of Barcroft, H., Peterson, E., and Schwab, R. S. (1952). Action of adrenaline and noradrenaline on the tremor in Parkinthe receptors concerned with physiological son's disease. Neurology (Minneap.), 2, 154-160.","journal-title":"Neurology (Minneap.); Action of adrenaline and noradrenaline on the tremor in Parkinthe receptors concerned with physiological son's disease"},{"key":"ref_2","article-title":"tremor is in the forearm","volume-title":"In the very few pathological studies of patients with essential tremor no definite organic lesion has been found which might be correlated with the appearance of tremor (Herskovits and Blackwood, 1969), and there appears to be no real argument against the theory that this condition is a functional rather than a structural disorder. If, as seems likely, essential tremor repre","year":"1967","unstructured":"tremor is in the forearm (Marsden et al., 1967). In the very few pathological studies of patients with essential tremor no definite organic lesion has been found which might be correlated with the appearance of tremor (Herskovits and Blackwood, 1969), and there appears to be no real argument against the theory that this condition is a functional rather than a structural disorder. If, as seems likely, essential tremor repre-"},{"issue":"1888","key":"ref_3","first-page":"563","article-title":"Encore la choree chronique. Chor6e chronique hemilat6rale avec demence chez une femme de 49 ans-quelques remarques a ce propos sur le tremblement hereditaire et le tremblement senile. In Lefons du Mardi a la Salpetriere","volume":"1887","author":"Charcot, J.N.","year":"1888","unstructured":"Charcot, J. N. (1888). Encore la choree chronique. Chor6e chronique hemilat6rale avec demence chez une femme de 49 ans-quelques remarques a ce propos sur le tremblement hereditaire et le tremblement senile. In Lefons du Mardi a la Salpetriere. Policliniques, 1887-1888, pp. 563-566. Delahaye: Paris.","journal-title":"Policliniques"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1136\/jnnp.25.2.116","article-title":"The effects of adrenaline, noradrenaline, and isoprenaline on Parkinsonian tremor","volume":"25","author":"Constas, C.","year":"1962","unstructured":"Constas, C. (1962). The effects of adrenaline, noradrenaline, and isoprenaline on Parkinsonian tremor. Journal of Neurology, Neurosurgery, and Psychiatry, 25, 116-121.","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00000441-188710000-00005","article-title":"Hereditary tremor, a hitherto undescribed form of motor neurosis","volume":"94","author":"Dana, C.L.","year":"1887","unstructured":"Dana, C. L. (1887). Hereditary tremor, a hitherto undescribed form of motor neurosis. American Journal of Medical Science, 94, 386-393.","journal-title":"American Journal of Medical Science"},{"key":"ref_6","first-page":"219","article-title":"propranolol does have other pharmacological actions, for it is also a central nervous depressant","volume":"55","author":"However","year":"1964","unstructured":"However, propranolol does have other pharmacological actions, for it is also a central nervous depressant (Murmann, Almirante, and Gibson, H. B. (1964). The Spiral Maze; a psychomotor test with implications for the study of delinquency. British Journal of Psychology, 55, 219-225.","journal-title":"British Journal of Psychology; The Spiral Maze; a psychomotor test with implications for the study of delinquency"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1136\/jnnp.8.3-4.57","article-title":"Static tremor in anxiety states","volume":"8","author":"Graham, J.D.P.","year":"1945","unstructured":"Graham, J. D. P. (1945). Static tremor in anxiety states. Journal of Neurology, Neurosurgery, and Psychiatry, 8, 57-","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"ref_8","first-page":"892","article-title":"Action of pronetholol on parkinsonian tremor","volume":"2","author":"Herring, A.B.","year":"1964","unstructured":"Herring, A. B. (1964). Action of pronetholol on parkinsonian tremor. Lancet, 2, 892-894. Saccani-Guelfi, 1966). The central mechanism in the response of tremor to stress is uncertain, but it has been suggested that corticofugal impulses influence tremor (Jung and Hassler, 1960).","journal-title":"Lancet; The central mechanism in the response of tremor to stress is uncertain, but it has been suggested that corticofugal impulses influence tremor"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/jnnp.32.6.509","article-title":"Essential (familial, hereditary) tremor: a case report","volume":"32","author":"Herskovits, E.; Blackwood, W.","year":"1969","unstructured":"Herskovits, E., and Blackwood, W. (1969). Essential (familial, hereditary) tremor: a case report. Journal of Neurology, Neurosurgery, and Psychiatry, 32, 509-511.","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"ref_10","first-page":"863","volume-title":"The extrapyramidal motor system. In Handbook of Physiology; Section 1. Neurophysiology","volume":"2","author":"Jung, R.; Hassler, R.","year":"1960","unstructured":"Jung, R., and Hassler, R. (1960). The extrapyramidal motor system. In Handbook of Physiology; Section 1. Neurophysiology. Vol. 2, pp. 863-927. Edited by J. Field, H. W. Magoun, and V. E. Hall. American Physiological Society: Washington."},{"key":"ref_11","first-page":"53","volume":"33","author":"Marsden, C.D.; Foley, T.H.; Owen, D.A.L.; McAllister, R.G.","year":"1967","unstructured":"Marsden, C. D., Foley, T. H., Owen, D. A. L., and McAllister, R. G. (1967). Peripheral P-adrenergic receptors concerned with tremor. Clinical Science, 33, 53-65.","journal-title":"Clinical Science"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1530\/acta.0.0570353","article-title":"Effect of, Badrenergic blockade on finger tremor and Achilles reflex time in anxious and thyrotoxic patients","volume":"57","author":"Marsden, C.D.; Gimlette, T.M.D.; McAllister, R.G.; Owen, D.A.L.; Miller, T.N.","year":"1968","unstructured":"Marsden, C. D., Gimlette, T. M. D., McAllister, R. G., Owen, D. A. L., and Miller, T. N. (1968). Effect of,Badrenergic blockade on finger tremor and Achilles reflex time in anxious and thyrotoxic patients. Acta Endocrinologica, 57, 353-362.","journal-title":"Acta Endocrinologica"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1136\/jnnp.25.2.122","article-title":"Observations on essential tremor","volume":"25","author":"Marshall, J.","year":"1962","unstructured":"Marshall, J. (1962). Observations on essential tremor. Journal of Neurology, Neurosurgery, and Psychiatry, 25, 122-125.","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/brain\/95.3.573","article-title":"A method of recording and analysing intention tremor","volume":"95","author":"Morgan, M.H.; Hewer, R.L.; Cooper, R.","year":"1972","unstructured":"Morgan, M. H., Hewer, R. L., and Cooper, R. (1972). A method of recording and analysing intention tremor. Brain, 95, 573-578.","journal-title":"Brain"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.2042-7158.1966.tb07878.x","article-title":"Central nervous system effects of four f-adrenergic receptor blocking agents","volume":"18","author":"Murmann, W.; Almirante, L.; Saccani-Guelfi, M.","year":"1966","unstructured":"Murmann, W., Almirante, L., and Saccani-Guelfi, M. (1966). Central nervous system effects of four f-adrenergic receptor blocking agents. Journal of Pharmacy and Pharmacology, 18, 317-318.","journal-title":"Journal of Pharmacy and Pharmacology"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/S0140-6736(65)92279-8","article-title":"Effect of adrenergic fl-blockage on Parkinsonian tremor","volume":"2","author":"Owen, D.A.L.; Marsden, C.D.","year":"1965","unstructured":"Owen, D. A. L., and Marsden, C. D. (1965). Effect of adrenergic fl-blockage on Parkinsonian tremor. Lancet, 2, 1259-1262.","journal-title":"Lancet"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1136\/jnnp.20.4.302","article-title":"Frequency analysis of physiological and neurotic tremors","volume":"20","author":"Redfearn, J.W.T.","year":"1957","unstructured":"Redfearn, J. W. T. (1957). Frequency analysis of physiological and neurotic tremors. Journal of Neurology, Neurosurgery, and Psychiatry, 20, 302-313.","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1136\/jnnp.28.5.404","article-title":"Clinical trial with a beta-receptor antagonist (propranolol) in Parkinsonism","volume":"28","author":"Strang, R.R.","year":"1965","unstructured":"Strang, R. R. (1965). Clinical trial with a beta-receptor antagonist (propranolol) in Parkinsonism. Journal of Neurology, Neurosurgery, and Psychiatry, 28, 404-406.","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"ref_19","first-page":"66","article-title":"The control of essential tremor by propranolol","volume":"96","author":"Winkler, G.F.; Young, R.R.","year":"1972","unstructured":"Winkler, G. F., and Young, R. R. (1972). The control of essential tremor by propranolol. Transactions of the American Neurological Association, 96, 66-68.","journal-title":"Transactions of the American Neurological Association"}],"container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.36.4.618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T02:29:06Z","timestamp":1601087346000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.36.4.618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,8,1]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1973,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.36.4.618","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1973,8,1]]}}}