{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:33:52Z","timestamp":1758630832600},"reference-count":37,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"published-print":{"date-parts":[[1984,3,1]]},"DOI":"10.1136\/jnnp.47.3.241","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T21:16:40Z","timestamp":1226351800000},"page":"241-249","source":"Crossref","is-referenced-by-count":22,"title":["Central nervous system involvement in optic neuritis."],"prefix":"10.1136","volume":"47","author":[{"given":"E A","family":"Sanders","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J P","family":"Reulen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L A","family":"Hogenhuis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"641","article-title":"Troubles oculaires de la sclerose en plaques","volume":"12","author":"Parinaud, H.","year":"1884","unstructured":"Parinaud H. Troubles oculaires de la sclerose en plaques. Prog Med (Paris), 1884;12:641.","journal-title":"Prog Med (Paris)"},{"key":"ref_2","first-page":"313","article-title":"Ueber Augenstorungen bei Multipeler Sklerose","volume":"3","author":"Gnauck, R.","year":"1884","unstructured":"Gnauck R. Ueber Augenstorungen bei Multipeler Sklerose. Neurol Zbl 1884;3:313.","journal-title":"Neurol Zbl"},{"issue":"21","key":"ref_3","first-page":"303","article-title":"Untersuchungen uber die bei der Multipeler Herdsklerose vorkommende Augenstorungen","volume":"1889","author":"Uhthoff, W.","unstructured":"Uhthoff W. Untersuchungen uber die bei der Multipeler Herdsklerose vorkommende Augenstorungen. Arch Psychiat Nervenkr 1889;21(55): 303.","journal-title":"Arch Psychiat Nervenkr"},{"key":"ref_4","first-page":"217","article-title":"GW eds","author":"Vinken, P.J.; Bruyn","year":"1970","unstructured":"Vinken, PJ, Bruyn GW eds, Amsterdam, North-Holland Publ Co, 1970, p. 217-309."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1212\/WNL.26.6_Part_2.26","article-title":"Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States","volume":"II:","author":"Ikuta, F.; Zimmerman, H.M.","year":"1976","unstructured":"Ikuta F, Zimmerman HM. Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States. Neurology (Minneap) 1976; part II:26-28.","journal-title":"Neurology (Minneap)"},{"key":"ref_6","article-title":"Multiple Sclerosis. A reappraisal","author":"McAlpine, D.; Lumsden, C.E.; Acheson, E.D.","year":"1965","unstructured":"McAlpine D, Lumsden CE, Acheson ED. Multiple Sclerosis. A reappraisal. Edinburgh, Livingstone Ltd, 1965."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1001\/archneur.1966.00470110003001","article-title":"Clinical studies of multiple sclerosis in Israel. IV. Optic neuropathy and multiple sclerosis","volume":"14","author":"Leibowitz, U.; Alter, M.; Halpern, L.","year":"1966","unstructured":"Leibowitz U, Alter M, Halpern L. Clinical studies of multiple sclerosis in Israel. IV. Optic neuropathy and multiple sclerosis. Arch Neurol 1966;14:459.","journal-title":"Arch Neurol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1212\/WNL.29.2.208","article-title":"A prospective study of the risk of developing multiple sclerosis in uncomplicated optic neuritis","volume":"29","author":"Cohen, M.M.; Lessell, S.; Wole, P.A.","year":"1979","unstructured":"Cohen MM, Lessell S, Wole PA. A prospective study of the risk of developing multiple sclerosis in uncomplicated optic neuritis. Neurology (Minneap) 1979;29:208-13.","journal-title":"Neurology (Minneap)"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1600-0404.1975.tb05771.x","article-title":"Optic neuritis: studies on the cerebrospinal fluid in relation to clinical course in 61 patients","volume":"52","author":"Sandberg-Wollheim, M.","year":"1975","unstructured":"Sandberg-Wollheim M. Optic neuritis: studies on the cerebrospinal fluid in relation to clinical course in 61 patients. Acta Neurol Scand 1975;52:167-8.","journal-title":"Acta Neurol Scand"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/ana.410090606","article-title":"Prognosis of optic neuritis with special reference to cerebrospinal fluid immunoglobulins and measles virus antibodies","volume":"9","author":"Nikoskelainen, E.; Frey, H.; Salmi, A.","year":"1981","unstructured":"Nikoskelainen E, Frey H, Salmi A. Prognosis of optic neuritis with special reference to cerebrospinal fluid immunoglobulins and measles virus antibodies. Ann Neurol 1981;9:545-50.","journal-title":"Ann Neurol"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1136\/jnnp.34.3.275","article-title":"Visually evoked responses in multiple sclerosis","volume":"34","author":"Richey, E.T.; Kooi, K.A.; Tourtelotte, W.W.","year":"1971","unstructured":"Richey ET, Kooi KA, Tourtelotte WW. Visually evoked responses in multiple sclerosis. J Neurol Neurosurg Psychiat 1971;34:275-80.","journal-title":"J Neurol Neurosurg Psychiat"},{"key":"ref_12","article-title":"Delayed visual evoked response in optic neuritis","author":"Halliday, A.M.; McDonald, W.I.; Mushin, J.","year":"1972","unstructured":"Halliday AM, McDonald WI, Mushin J. Delayed visual evoked response in optic neuritis. Lancet 1972;932985.","journal-title":"Lancet"},{"key":"ref_13","first-page":"522","article-title":"Problems of experimental trials of therapy in multiple sclerosis: report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis","volume":"122","author":"Schumacher, G.A.; Beebe, G.; Kibler, R.F.","year":"1965","unstructured":"Schumacher GA, Beebe G, Kibler RF et al. Problems of experimental trials of therapy in multiple sclerosis: report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis. Ann New York Acad Sci 1965;122:522-86.","journal-title":"Ann New York Acad Sci"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/S0140-6736(75)93138-4","article-title":"Auditory evoked responses in multiple sclerosis","volume":"24","author":"Robinson, K.; Rudge, P.","year":"1975","unstructured":"Robinson K, Rudge P. Auditory evoked responses in multiple sclerosis. Lancet 1975;24: 1164-6.","journal-title":"Lancet"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/brain\/100.1.19","article-title":"Abnormalities of the auditory evoked potentials in patients with multiple sclerosis","volume":"100","author":"Robinson, K.; Rudge, P.","year":"1977","unstructured":"Robinson K, Rudge P. Abnormalities of the auditory evoked potentials in patients with multiple sclerosis. Brain 1977;100:19-40.","journal-title":"Brain"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0022-510X(78)90004-7","article-title":"The cervical somatosensory evoked potential (SEP) in the diagnosis of multiple sclerosis","volume":"35","author":"Small, D.G.; Matthews, W.B.; Small, M.","year":"1978","unstructured":"Small DG, Matthews WB, Small M. The cervical somatosensory evoked potential (SEP) in the diagnosis of multiple sclerosis. J Neurol Sci 1978;35:211-24.","journal-title":"J Neurol Sci"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1212\/WNL.31.3.272","article-title":"Light-stimulus-evoked blink reflex: methods, normal values, relation to other blink reflexes and observations in multiple sclerosis","volume":"31","author":"Yates, S.K.; Brown, W.F.","year":"1981","unstructured":"Yates SK, Brown WF. Light-stimulus-evoked blink reflex: methods, normal values, relation to other blink reflexes and observations in multiple sclerosis. Neurology (Minneap) 1981;31:272-81.","journal-title":"Neurology (Minneap)"},{"issue":"2","key":"ref_18","first-page":"147","article-title":"Apport de l'epreuve vestibulaire rotatoire pendulaire au diagnostic de la form spinale de la sclerose en plaques","volume":"137","author":"Scarpaloz, S.; Tsalanikas, C.; Stanboulis, E.","year":"1981","unstructured":"Scarpaloz S, Tsalanikas C, Stanboulis E. Apport de l'epreuve vestibulaire rotatoire pendulaire au diagnostic de la form spinale de la sclerose en plaques. Rev Neurol (Paris) 1981;137 (2):147-51.","journal-title":"Rev Neurol (Paris)"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/brain\/106.1.121","article-title":"Eye movement disorders in multiple sclerosis and optic neuritis","volume":"106","author":"Reulen, J.P.H.; Sanders, E.A.C.M.; Hogenhuis, L.A.H.","year":"1983","unstructured":"Reulen JPH, Sanders EACM, Hogenhuis LAH. Eye movement disorders in multiple sclerosis and optic neuritis. Brain 1983;106:121-40.","journal-title":"Brain"},{"key":"ref_20","first-page":"67","article-title":"Evoked potentials with special reference to the diagnostic value in multiple sclerosis","volume":"67","author":"Kjear, M.","year":"1983","unstructured":"Kjear M. Evoked potentials with special reference to the diagnostic value in multiple sclerosis. Acta Neurol Scand 1983;67:67-89.","journal-title":"Acta Neurol Scand"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1600-0404.1976.tb04356.x","article-title":"Computer tomography of the brain in multiple sclerosis. A radiological study of 110 patients with special reference to demonstration of cerebral plaques","volume":"53","author":"Gyldensted, C.","year":"1976","unstructured":"Gyldensted C. Computer tomography of the brain in multiple sclerosis. A radiological study of 110 patients with special reference to demonstration of cerebral plaques. Acta Neurol Scand 1976;53:386-89.","journal-title":"Acta Neurol Scand"},{"issue":"3","key":"ref_22","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1212\/WNL.28.3.251","article-title":"Cranial CT appearances of acute multiple sclerosis","volume":"28","author":"Aita, J.F.; Bennett, D.R.; Anderson, R.E.; Zitter, F.","year":"1978","unstructured":"Aita JF, Bennett DR, Anderson RE, Zitter F. Cranial CT appearances of acute multiple sclerosis. Neurology (Minneap) 1978;28(3):251-55.","journal-title":"Neurology (Minneap)"},{"issue":"3","key":"ref_23","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0022-510X(78)90048-5","article-title":"Computerized tomography of brain and optic nerve in multiple sclerosis. Observations in 100 patients, including serial studies in 16","volume":"36","author":"Cala, L.A.; Mastaglia, F.L.; Black, J.L.","year":"1978","unstructured":"Cala LA, Mastaglia FL, Black JL. Computerized tomography of brain and optic nerve in multiple sclerosis. Observations in 100 patients, including serial studies in 16. J Neurol Sci 1978;36(3):411-26.","journal-title":"J Neurol Sci"},{"issue":"3","key":"ref_24","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF00329059","article-title":"Iodide and xenon enhancement of computed tomography (CT) in multiple sclerosis (MS)","volume":"15","author":"Radue, E.W.; Kendall, B.E.","year":"1978","unstructured":"Radue EW, Kendall BE. Iodide and xenon enhancement of computed tomography (CT) in multiple sclerosis (MS). Neuroradiology 1978;15(3): 153-8.","journal-title":"Neuroradiology"},{"issue":"2","key":"ref_25","doi-asserted-by":"crossref","first-page":"213","DOI":"10.2214\/ajr.132.2.213","article-title":"Eldevik 0. CT detection of demyelinated plaques in multiple sclerosis","volume":"132","author":"Haughton, V.M.; Ho, K.C.; Williams, A.L.","year":"1979","unstructured":"Haughton VM, Ho KC, Williams AL, Eldevik 0. CT detection of demyelinated plaques in multiple sclerosis. AJR 1979;132(2):213-5.","journal-title":"AJR"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF00313952","article-title":"Pattern and flash visual evoked responses in multiple sclerosis","volume":"220","author":"Neetens, A.; Y, Hendrata; J, Van Rompaey","year":"1979","unstructured":"Neetens, A, Hendrata Y, Van Rompaey J. Pattern and flash visual evoked responses in multiple sclerosis. J Neurol 1979;220: 113-24.","journal-title":"J Neurol"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/brain\/98.2.261","article-title":"Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis","volume":"98","author":"Asselman, P.; Chadwick, D.W.; Marsden, C.D.","year":"1975","unstructured":"Asselman P, Chadwick DW, Marsden CD. Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis. Brain 1975;98:261-82.","journal-title":"Brain"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/BF01833159","article-title":"Visual evoked potentials (VEP) elicited by checkerboard versus foveal stimulation in multiple sclerosis. A clinical study in 235 patients","volume":"229","author":"Oepen, G.; CHR, Brauner; M, Doerr; U, Thoden","year":"1981","unstructured":"Oepen, G, Brauner CHR, Doerr M, Thoden U. Visual evoked potentials (VEP) elicited by checkerboard versus foveal stimulation in multiple sclerosis. A clinical study in 235 patients. Arch Psychiat Nervenkr 1981;229:305-13.","journal-title":"Arch Psychiat Nervenkr"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1093\/brain\/94.4.681","article-title":"Auditory evoked far fields averaged from the scalp of humans","volume":"94","author":"Jewett, D.L.; Williston, J.S.","year":"1971","unstructured":"Jewett DL, Williston JS. Auditory evoked far fields averaged from the scalp of humans. Brain 1971;94:681-96.","journal-title":"Brain"},{"issue":"11","key":"ref_30","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1136\/jnnp.37.11.1225","article-title":"Electromyographic and reflex study in idiopathic and symptomatic trigeminal neuralgias: latency of the jaw and blink reflex","volume":"37","author":"de Visser BW, Ongerboer; C, Goor","year":"1974","unstructured":"Ongerboer de Visser BW, Goor C. Electromyographic and reflex study in idiopathic and symptomatic trigeminal neuralgias: latency of the jaw and blink reflex. J Neurol Neurosurg Psychiatry 1974;37(11): 1225-30.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0019-2791(65)90004-2","article-title":"Immunochemical Quantification ofAntigens by Single Radial Immunodiffusion","volume":"2","author":"Mancini, G.; Carbonara, A.O.; Heremans, J.F.","year":"1965","unstructured":"Mancini G, Carbonara AO, Heremans JF. Immunochemical Quantification ofAntigens by Single Radial Immunodiffusion. Immunochemistry 1965;2:235-44.","journal-title":"Immunochemistry"},{"key":"ref_32","first-page":"334","article-title":"Gel isoelectric focussing of cerebrospinal fluid proteins: a potential diagnostic tool","volume":"9","author":"Delmotte, P.","year":"1971","unstructured":"Delmotte P. Gel isoelectric focussing of cerebrospinal fluid proteins: a potential diagnostic tool. J Clin Chem Biochem 1971;9:334.","journal-title":"J Clin Chem Biochem"},{"issue":"39","key":"ref_33","first-page":"655","article-title":"Follow-up on patients with a history of optic neuritis","volume":"1961","author":"Hyllenstedt, K.; Moller, D.M.","unstructured":"Hyllenstedt K, Moller DM. Follow-up on patients with a history of optic neuritis. Acta Ophthalmol 1961;39:655-62.","journal-title":"Acta Ophthalmol"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1136\/jnnp.40.10.1009","article-title":"Pattern reversal evoked visual potential in the diagnosis of multiple sclerosis","volume":"40","author":"Matthews, W.B.; Small, D.G.; Small, M.; Putney, E.","year":"1977","unstructured":"Matthews WB, Small DG, Small M, Putney E. Pattern reversal evoked visual potential in the diagnosis of multiple sclerosis. J Neurol Neurosurg Psychiatry 1977;40: 1009-14.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"ref_35","first-page":"269","article-title":"Risk of multiple sclerosis in isolated optic neuritis","volume":"9","author":"Feasby, T.E.; Ebers, G.C.","year":"1982","unstructured":"Feasby TE, Ebers GC. Risk of multiple sclerosis in isolated optic neuritis. J Can Sci Neurol 1982:9(2):269.","journal-title":"J Can Sci Neurol"},{"key":"ref_36","first-page":"443","article-title":"cases of optic neuritis","volume":"49","year":"1973","unstructured":"cases of optic neuritis. Acta Neurol Scand 1973;49:443-53.","journal-title":"Acta Neurol Scand"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1136\/jnnp.39.3.283","article-title":"Acute optic neuritis and the prognosis for multiple sclerosis","volume":"39","author":"Hutchinson, W.M.","year":"1976","unstructured":"Hutchinson WM. Acute optic neuritis and the prognosis for multiple sclerosis. J Neurol Neurosurg Psychiatry 1976;39:283-9.","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.47.3.241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T04:04:47Z","timestamp":1601093087000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.47.3.241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,3,1]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1984,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.47.3.241","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1984,3,1]]}}}