{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:53:38Z","timestamp":1760982818281},"reference-count":12,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"published-print":{"date-parts":[[1986,11,1]]},"DOI":"10.1136\/jnnp.49.11.1324","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T21:16:40Z","timestamp":1226351800000},"page":"1324-1325","source":"Crossref","is-referenced-by-count":10,"title":["Meige's syndrome and palatal myoclonus associated with brain stem stroke. A common mechanism?"],"prefix":"10.1136","volume":"49","author":[{"given":"T J","family":"Day","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R B","family":"Lefroy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F L","family":"Mastaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1212\/WNL.33.9.1237","article-title":"Blepharospasm associated with brainstem lesions","volume":"33","author":"Jankovic, J.; Patel, S.C.","year":"1983","unstructured":"Jankovic J, Patel SC. Blepharospasm associated with brainstem lesions. Neurology (Cleveland) 1983;33:1237-40.","journal-title":"Neurology (Cleveland)"},{"key":"ref_2","first-page":"1522","article-title":"Blepharospasm associated with palatal myoclonus. Neurology (Cleveseen on inspection of the oral cavity, and tongue movements were slow. Facial and palatal sensation were normal. The jaw jerk was not exaggerated. There was a mild residual right hemiparesis involving the face, arm and leg, with hyper-reflexia and a Babinski response on the right side. Dys-Palatal myoclonus may be caused by a variety of lesions involving one limb of the dentato-rubro-olivary (Guillain-Mollaret) triangle, including stroke, demyelination, tumour, arteriovenous malformation","volume":"34","author":"Lang, A.E.; Sharp, J.A.","year":"1984","unstructured":"Lang AE, Sharp JA. Blepharospasm associated with palatal myoclonus. Neurology (Cleveseen on inspection of the oral cavity, and tongue movements were slow. Facial and palatal sensation were normal. The jaw jerk was not exaggerated. There was a mild residual right hemiparesis involving the face, arm and leg, with hyper-reflexia and a Babinski response on the right side. Dys-Palatal myoclonus may be caused by a variety of lesions involving one limb of the dentato-rubro-olivary (Guillain-Mollaret) triangle, including stroke, demyelination, tumour, arteriovenous malformation, land) 1984;34:1522."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ana.410050111","article-title":"Palatal myoclonus and denervation supersensitivity in the central nervous system","volume":"5","author":"Matsuo, F.; Ajax, E.T.","year":"1979","unstructured":"Matsuo F, Ajax ET. Palatal myoclonus and denervation supersensitivity in the central nervous system. Ann Neurol 1979;5:72-78.","journal-title":"Ann Neurol"},{"issue":"2","key":"ref_4","first-page":"437","article-title":"Les convulsions de la face: une forme clinique de convulsion faciale, bilaterale et mediane","volume":"1910","author":"Meige, H.","unstructured":"Meige H. Les convulsions de la face: une forme clinique de convulsion faciale, bilaterale et mediane. Rev Neurol (Paris) 1910;2:437-43.","journal-title":"Rev Neurol (Paris)"},{"key":"ref_5","first-page":"402","article-title":"Blepharospasm and metria and dysdiadochokinesis were present trauma, encephalitis and syphilis.7 8 A delay orofacial-cervical dystonia: clinical and pharin the left arm and leg. The gait was widebased and hemiplegic, with a tendency to fall to the right. Sensory testing showed no abnormality. A cranial CT scan performed 6 weeks after the second stroke showed a nonenchancing low-density lesion on the left side of the rostral pons (fig 1). Auditory of 2-49 months has been noted in the onset of the myoclonus after acute lesions suggesting that the mechanism of the myoclonus may involve the development of denervation hypersensitivity in olivary neurons.3 An alternative mechanism postulates release of olivary neurons from supramacological findings in 100 patients","volume":"13","author":"Jankovic, J.; Ford, J.","year":"1983","unstructured":"Jankovic J, Ford J. Blepharospasm and metria and dysdiadochokinesis were present trauma, encephalitis and syphilis.7 8 A delay orofacial-cervical dystonia: clinical and pharin the left arm and leg. The gait was widebased and hemiplegic, with a tendency to fall to the right. Sensory testing showed no abnormality. A cranial CT scan performed 6 weeks after the second stroke showed a nonenchancing low-density lesion on the left side of the rostral pons (fig 1). Auditory of 2-49 months has been noted in the onset of the myoclonus after acute lesions suggesting that the mechanism of the myoclonus may involve the development of denervation hypersensitivity in olivary neurons.3 An alternative mechanism postulates release of olivary neurons from supramacological findings in 100 patients. Ann Neurol 1983;13:402-1 1.","journal-title":"Ann Neurol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1136\/jnnp.39.12.1204","article-title":"Blepharospasm-oromandibular dystonia syndrome (Brueghel's syndrome)","volume":"39","author":"Marsden, C.D.","year":"1976","unstructured":"Marsden CD. Blepharospasm-oromandibular dystonia syndrome (Brueghel's syndrome). J Neurol Neurosurg Psychiatry 1976;39:1204-9.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1001\/archneurpsyc.1956.02330210065007","volume":"75","author":"Nathanson, M.","year":"1956","unstructured":"Nathanson M. Palatal myoclonus. Arch Neurol Psychiatry 1956;75:285-96.","journal-title":"Palatal myoclonus. Arch Neurol Psychiatry"},{"key":"ref_8","article-title":"Palatal brain stem evoked responses with monaural segmental inhibition.9 Meige's syndrome is myoclonus","author":"Herrmann, C.; Crandall, P.H.; Fang, H.C.H.","year":"1957","unstructured":"Herrmann C, Crandall PH, Fang HCH. Palatal brain stem evoked responses with monaural segmental inhibition.9 Meige's syndrome is myoclonus. Neurology (Minneap) 1957;7: click stimulation showed attenuation of waves I-V with left ear stimulation, and absence of wave III. With right ear stimulation the I-V interval was prolonged.","journal-title":"Neurology (Minneap); 7: click stimulation showed attenuation of waves I-V with left ear stimulation, and absence of wave III. With right ear stimulation the I-V interval was prolonged"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/0022-510X(67)90086-X","article-title":"Palatal myoclonus: a reappraisal","volume":"5","author":"Herrmann, C.; Brown, J.W.","year":"1967","unstructured":"Herrmann C, Brown JW. Palatal myoclonus: a reappraisal. J Neurol Sci 1967;5:473-92.","journal-title":"J Neurol Sci"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1212\/WNL.35.2.283-b","article-title":"Blepharospasm due to unilateral diencephalon infarction","volume":"35","author":"Powers, J.M.","year":"1985","unstructured":"Powers JM. Blepharospasm due to unilateral diencephalon infarction. Neurology (Cleveland) 1985;35:283-4.","journal-title":"Neurology (Cleveland)"},{"key":"ref_11","first-page":"69","article-title":"nections with probable involvement of the movements was usually delayed for several","year":"1977","unstructured":"nections with probable involvement of the movements was usually delayed for several McGraw-Hill 1977:69-79."},{"key":"ref_12","article-title":"right dentato-rubral tract in the midbrain. months after the acute episode, again raising The lesion demonstrated in the pons by CT after the second stroke is likely to represent the possibility of a denervation hypersensitivity of facial motor neurons or a Accepted","volume-title":"an infarct resulting from occlusion of one of release of facial motor neurons from suprathe perforating branches of the basilar nuclear inhibition. The association of the artery and was appropriately placed to protwo disorders, as in the present case, has duce the right hemiparesis, left-sided cerebeen reported only rarely2 5 and suggests bellar signs and palatal myoclonus due to that similar pathophysiological mechanisms involvement of the central tegmental tract. may be involved in the development of the On the other hand, the myoclonus may have two involuntary movements","year":"1985","unstructured":",right dentato-rubral tract in the midbrain. months after the acute episode, again raising The lesion demonstrated in the pons by CT after the second stroke is likely to represent the possibility of a denervation hypersensitivity of facial motor neurons or a Accepted 8 August 1985 an infarct resulting from occlusion of one of release of facial motor neurons from suprathe perforating branches of the basilar nuclear inhibition. The association of the artery and was appropriately placed to protwo disorders, as in the present case, has duce the right hemiparesis, left-sided cerebeen reported only rarely2 5 and suggests bellar signs and palatal myoclonus due to that similar pathophysiological mechanisms involvement of the central tegmental tract. may be involved in the development of the On the other hand, the myoclonus may have two involuntary movements."}],"container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.49.11.1324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T04:11:40Z","timestamp":1601093500000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.49.11.1324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,11,1]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1986,11,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.49.11.1324","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1986,11,1]]}}}