{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:35:03Z","timestamp":1791333303795,"version":"4.3.1"},"reference-count":12,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"published-print":{"date-parts":[[1988,4,1]]},"DOI":"10.1136\/jnnp.51.4.588","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T21:16:40Z","timestamp":1226351800000},"page":"588-590","source":"Crossref","is-referenced-by-count":2,"title":["Akinetic mutism in Wernicke-Korsakoff disease: a case report."],"prefix":"10.1136","volume":"51","author":[{"given":"M W","family":"Mann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J D","family":"Degos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"244","article-title":"De ease: a case report Mendilaharsu S. Prolonged and monosymptomatic dysphasic status epilepticus. Sir: Akinetic mutism, first described by","volume":"26","author":"E, I.De Pasquet; E, Guadin; A, Bianchi","year":"1976","unstructured":"I De Pasquet E, Guadin E, Bianchi A, De ease: a case report Mendilaharsu S. Prolonged and monosymptomatic dysphasic status epilepticus. Sir: Akinetic mutism, first described by Neurology 1976;26:244-7.","journal-title":"Neurology"},{"key":"ref_2","article-title":"A 74 year old woman was admitted to hospital on 5 August. 1985 with dehydration, vertigo and cardiac arrythmia. According to Arterial blood pressure was 100\/50 mm Hg, and the pulse rate 80\/min","unstructured":"A 74 year old woman was admitted to hospital on 5 August. 1985 with dehydration, vertigo and cardiac arrythmia. According to Arterial blood pressure was 100\/50 mm Hg, and the pulse rate 80\/min."},{"key":"ref_3","article-title":"The association of Wernicke's encephasure on the retromandibular branch of the The diagnosis of Wernicke's encephalopathy and akinetic mutism has been sugfacial nerve and no defence reaction at all to lopathy in our case is proved by a history of gested by Nielsen,3 though his description this manoeuvre. Body temperature was chronic alcoholism, oculomotor paralysis, lacks detail. His patient, a 70 year old male","unstructured":"The association of Wernicke's encephasure on the retromandibular branch of the The diagnosis of Wernicke's encephalopathy and akinetic mutism has been sugfacial nerve and no defence reaction at all to lopathy in our case is proved by a history of gested by Nielsen,3 though his description this manoeuvre. Body temperature was chronic alcoholism, oculomotor paralysis, lacks detail. His patient, a 70 year old male"},{"key":"ref_4","article-title":"Letters ing the red nucleus, within the mesenerable attention,' but few case reports of Computed tomography (CT) performed cephalic tegmentum, the left inferior cognitive deficits due to lesions localised to on 6 October 1986 (on the 17th day from colliculus and the mammillary bodies.\" the basal ganglia have appeared in the literaonset) showed a small low density area in These findings were compatible with ture. We report a case of denial of hemithe head of the left caudate nucleus","unstructured":"Letters ing the red nucleus, within the mesenerable attention,' but few case reports of Computed tomography (CT) performed cephalic tegmentum, the left inferior cognitive deficits due to lesions localised to on 6 October 1986 (on the 17th day from colliculus and the mammillary bodies.\" the basal ganglia have appeared in the literaonset) showed a small low density area in These findings were compatible with ture. We report a case of denial of hemithe head of the left caudate nucleus (approx-"},{"key":"ref_5","article-title":"or to the globus pallidus, and no other ceptive stimulation, forty hours after the A 51 year old right-handed man was abnormalities were seen. Enhancement after start of thiamine therapy their patient was admitted to Kawasaki Seitetsu Chiba Hoscontrast infusion in the region of the left eating by himself and answering simple pital","volume-title":"caudate nucleus indicated recent infarction","year":"1986","unstructured":"or to the globus pallidus, and no other ceptive stimulation, forty hours after the A 51 year old right-handed man was abnormalities were seen. Enhancement after start of thiamine therapy their patient was admitted to Kawasaki Seitetsu Chiba Hoscontrast infusion in the region of the left eating by himself and answering simple pital (Chiba, Japan) on 22 September 1986, caudate nucleus indicated recent infarction."},{"key":"ref_6","first-page":"384","volume":"10","author":"Neurol","year":"1981","unstructured":";64:273-90."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/00005053-195311000-00006","article-title":"Wernicke's encephalopathy. Correlation of sites of lesions with symptomatology","volume":"118","author":"Nielsen, J.M.","year":"1953","unstructured":"Neurol 1981;10:384-7.","journal-title":"J Nerv Ment Dis"},{"key":"ref_8","article-title":"Diagnosis of Stupor and Coma","volume-title":"other patients to play and tried to undertake activities which were manifestly impossible. Moreover, when asked about his right limbs, he responded that they were fine or had recovered, despite the fact that viosensory abnormalities were observed in the right leg but rapidly disappeared and the patient was diagnosed as acute hemichorea. MRI clearly revealed a lesion localised to the head of the caudate nucleus con","author":"Plum, F.; Posner, J.","year":"1982","unstructured":"Nielsen JM. Wernicke's encephalopathy. Correlation of sites of lesions with symptomatology. J Nerv Ment Dis 1953;118:429-34.","edition":"3rd Ed"},{"key":"ref_9","article-title":"The lent involuntary movements were ongoing. tralateral to the involuntary movements. Wernicke-Korsakoff-Syndrome","author":"Victor, M.; Adams, R.D.; Collins, G.H.","year":"1971","unstructured":"Plum F, Posner J. Diagnosis of Stupor and Coma. 3rd Ed. Philadelphia: FA Davis Company, 1982. invited other patients to play and tried to undertake activities which were manifestly impossible. Moreover, when asked about his right limbs, he responded that they were fine or had recovered, despite the fact that viosensory abnormalities were observed in the right leg but rapidly disappeared and the patient was diagnosed as acute hemichorea. MRI clearly revealed a lesion localised to the head of the caudate nucleus con-"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0140-6736(78)91867-6","article-title":"Coma in the Wernicke-Korsakoff-syndrome","volume":"ii:","author":"Wallis, W.E.; Willoughby, E.; Baker, P.","year":"1978","unstructured":"Victor M, Adams RD, Collins GH. The lent involuntary movements were ongoing. tralateral to the involuntary movements. Wernicke-Korsakoff-Syndrome. Oxford: In this respect, he showed clear signs of Particularly noteworthy about this case Blackwell Scientific Publications, 1971.","journal-title":"Lancet"},{"key":"ref_11","first-page":"2","article-title":"Lehrbuch der Gehirnkrankheiten fuer Aerzte und Studierende","volume":"1881","author":"Wernicke, C.","unstructured":"Wallis WE, Willoughby E, Baker P. Coma in the Wernicke-Korsakoff-syndrome. Lancet 1978;ii:400-1."},{"key":"ref_12","article-title":"There was no exinction on double Weinstein3 has previously described a case Accepted","volume-title":"simultaneous tactile and visual stimulation. with diffuse brain tumour in which there was Facial recognition, identification of overdenial of involuntary movements, and Goldlapping figures (Poppelreuter), colour namblatt et al4 have also reported the denial of ing, limb and facial praxis to command, leftchorea in the acute stage in a case of hemi","author":"found","year":"1987","unstructured":"Wernicke C. Lehrbuch der Gehirnkrankheiten fuer Aerzte und Studierende. Berlin: Theodor-Fischer-Verlag, 1881:2:220-42."}],"container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.51.4.588","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T04:22:04Z","timestamp":1601094124000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.51.4.588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,4,1]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1988,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.51.4.588","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1988,4,1]]}}}