{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:53:38Z","timestamp":1760982818553},"reference-count":8,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"published-print":{"date-parts":[[1989,6,1]]},"DOI":"10.1136\/jnnp.52.6.732","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T21:16:40Z","timestamp":1226351800000},"page":"732-735","source":"Crossref","is-referenced-by-count":6,"title":["The efficacy of (+)-4-propyl-9-hydroxynaphthoxazine as adjunctive therapy in Parkinson's disease."],"prefix":"10.1136","volume":"52","author":[{"given":"W J","family":"Weiner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S A","family":"Factor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J R","family":"Sanchez-Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"569","article-title":"Ther","volume":"230","year":"1984","unstructured":"Ther 1984;230:569-76."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/S0140-6736(85)92627-3","article-title":"}4-propyl-9- hydroxynaphthoxazine. (PHNO), a new dopaminomimetic, in treatment of parkinsonism","volume":"ii:","author":"Stoessl, A.J.; Mak, E.; Calne, B.D.","year":"1985","unstructured":"Stoessl AJ, Mak E, Calne BD. (+ }4-propyl-9- hydroxynaphthoxazine. (PHNO), a new dopaminomimetic, in treatment of parkinsonism. Lancet 1985;ii: 1330-1.","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/mds.870020106","article-title":"Antiparkinsonian Activity of a Single Oral Dose of PHNO","volume":"2","author":"Grandas, F.; Quinn, N.; Critchley, P.; Rohan, A.; Marsen, C.D.; Stahl, S.M.","year":"1987","unstructured":"Grandas F, Quinn N, Critchley P, Rohan A, Marsen CD, Stahl SM. Antiparkinsonian Activity of a Single Oral Dose of PHNO. Movement Disorders 1987;2:47-51.","journal-title":"Movement Disorders"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1212\/WNL.38.10.1541","article-title":"PHNO [(+)- 4-propyl-9-hydroxynaphthoxazineJ: a new and effective anti-Parkinson's disease agent","volume":"38","author":"Meunter, M.D.; Ahlskog, J.E.; Bell, G.; McManis, P.","year":"1988","unstructured":"Meunter MD, Ahlskog JE, Bell G, McManis P. PHNO [(+)-4-propyl-9-hydroxynaphthoxazineJ: a new and effective anti-Parkinson's disease agent. Neurology 1988;38: 1541-5.","journal-title":"Neurology"},{"key":"ref_5","first-page":"145","article-title":"Intracerebro-ventricular infusion of (+ )-4-propyl-9hydroxynaphthoxazine reverses the behavioural effects of dopamine deficiency in rats","volume":"22","author":"Yebenes, J.G.; Fahn, S.; Jackson-Lewis, V.; Mena, M.A.","year":"1987","unstructured":"Yebenes JG, Fahn S, Jackson-Lewis V, Mena MA. Intracerebro-ventricular infusion of (+ )-4-propyl-9hydroxynaphthoxazine reverses the behavioural effects of dopamine deficiency in rats. Ann Neurol 1987;22: 145.","journal-title":"Ann Neurol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/mds.870020306","article-title":"PHNO, a Novel Dopamine Agonist, In Animal Models of Parkinsonism","volume":"2","author":"Koller, W.; Herbster, G.; Gordon, J.","year":"1987","unstructured":"Koller W, Herbster G, Gordon J. PHNO, a Novel Dopamine Agonist, In Animal Models of Parkinsonism. Movement Disorders 1987;2:193-9.","journal-title":"Movement Disorders"},{"issue":"1","key":"ref_7","first-page":"276","article-title":"The Efficacy of 4-Propyl-9-Hydroxynaphthoxazine (PHNO) in Parkinson's Disease","volume":"37","author":"Weiner, W.J.; Sanchez-Ramos, J.; Factor, S.A.; Hefti, F.","year":"1987","unstructured":"Weiner WJ, Sanchez-Ramos J, Factor SA, Hefti F. The Efficacy of 4-Propyl-9-Hydroxynaphthoxazine (PHNO) in Parkinson's Disease. Neurology 1987;37(suppl 1):276.","journal-title":"Neurology"},{"key":"ref_8","article-title":"West's syndrome In a lengthy letter to the Lancet, dated","volume-title":"West ofTunbridge described \"a very rare andsingular species ofconvulsion... the only case Ihave witnessed is in my own child.\" The child, nearly a year old, was healthy till 4 months ofage, then developed bobbings of the head forwards","author":"January, 1841, Dr W J","year":"26","unstructured":"West's syndrome In a lengthy letter to the Lancet, dated 26 January, 1841, Dr W J West ofTunbridge described \"a very rare andsingular species ofconvulsion... the only case Ihave witnessed is in my own child.\" The child, nearly a year old, was healthy till 4 months ofage, then developed bobbings of the head forwards, which"}],"container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.52.6.732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T04:27:44Z","timestamp":1601094464000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.52.6.732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6,1]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1989,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.52.6.732","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1989,6,1]]}}}