{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:24:58Z","timestamp":1760783098668},"reference-count":35,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"published-print":{"date-parts":[[1989,8,1]]},"DOI":"10.1136\/jnnp.52.8.1006","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T21:16:40Z","timestamp":1226351800000},"page":"1006-1009","source":"Crossref","is-referenced-by-count":33,"title":["Neuroleptic malignant syndrome: a case report with post-mortem brain and muscle pathology."],"prefix":"10.1136","volume":"52","author":[{"given":"E M","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Dawson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","article-title":"Drug-induced extrapyramidal syndromes","volume-title":"Handbook of Clinical Neurology","author":"J, I.Delay; P, Deniker","unstructured":"I Delay J, Deniker P. Drug-induced extrapyramidal syndromes. In: Vinken PJ, Bruyn GW, eds. Handbook of Clinical Neurology."},{"key":"ref_2","first-page":"248","article-title":"Diseases of the Basal Ganglia","volume":"6","year":"1968","unstructured":"Diseases of the Basal Ganglia. Amsterdam: North Holland Publishing Co., 1968;6:248-66."},{"key":"ref_3","first-page":"79","article-title":"The neuroleptic malignant syndrome","volume":"41","author":"CaroffSN","year":"1980","unstructured":"CaroffSN. The neuroleptic malignant syndrome. J Clin Psychiatry 1980;41:79-83.","journal-title":"J Clin Psychiatry"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1176\/ajp.142.10.1137","article-title":"Neuroleptic malignant syndrome","volume":"142","author":"Levenson, J.L.","year":"1985","unstructured":"Levenson JL. Neuroleptic malignant syndrome. Am J Psychiatry 1985;142: 1137-45.","journal-title":"Am J Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1192\/bjp.148.1.47","article-title":"Neurolpetic malignant syndrome","volume":"148","author":"Abbot, R.J.; Loizou, L.A.","year":"1986","unstructured":"Abbot RJ, Loizou LA. Neurolpetic malignant syndrome. Br J Psychiatry 1986;148:47-51.","journal-title":"Br J Psychiatry"},{"key":"ref_6","first-page":"33747","article-title":"The neuroleptic malignant syndrome: agent host interaction","volume":"73","author":"Shalev, A.; Munitz, H.","year":"1986","unstructured":"Shalev A, Munitz H. The neuroleptic malignant syndrome: agent host interaction. Acta Psychiatr Scand 1986;73:33747.","journal-title":"Acta Psychiatr Scand"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1192\/bjp.150.6.752","article-title":"The neuroleptic malignant syndrome, so-called, a survey of the world literature","volume":"150","author":"Kellam, A.M.P.","year":"1987","unstructured":"Kellam AMP. The neuroleptic malignant syndrome, so-called, a survey of the world literature. Br J Psychiatry 1987;150:752-9.","journal-title":"Br J Psychiatry"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/00221309.1987.9711053","article-title":"Neuroleptic malignant syndrome","volume":"114","author":"Murray, J.B.","year":"1987","unstructured":"Murray JB. Neuroleptic malignant syndrome. J Gen Psychol 1987;114:39-46.","journal-title":"J Gen Psychol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1176\/ajp.143.12.1587","article-title":"Symptoms of neuroleptic malignant syndrome in 82 consecutive inpatients","volume":"143","author":"Addonizio, G.; Susman, V.L.; Roth, S.D.","year":"1986","unstructured":"Addonizio G, Susman VL, Roth SD. Symptoms of neuroleptic malignant syndrome in 82 consecutive inpatients. Am J Psychiatry 1986;143:1587-90.","journal-title":"Am J Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1176\/ajp.143.10.1227","article-title":"Frequency and presentation of neuroleptic malignant syndrome in a large psychiatric hospital","volume":"143","author":"Pope, H.G.; Keck, P.E.; McElroy, S.L.","year":"1986","unstructured":"Pope HG, Keck PE, McElroy SL. Frequency and presentation of neuroleptic malignant syndrome in a large psychiatric hospital. Am J Psychiatry 1986;143:1227-33.","journal-title":"Am J Psychiatry"},{"key":"ref_11","first-page":"1334","article-title":"Frequency and presentation of neuroleptic malignant syndrome: a prospective study","volume":"144","author":"Keck, P.E.; Harrison, G.; Pope, H.G.; McElroy, S.L.","year":"1987","unstructured":"Keck PE, Harrison G, Pope HG, McElroy SL. Frequency and presentation of neuroleptic malignant syndrome: a prospective study. Am J Psychiatry 1987;144:1334-6.","journal-title":"Am J Psychiatry"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1136\/bmj.289.6453.1228-d","article-title":"Neuroleptic malignant syndrome induced by a single injection of haloperidol","volume":"289","author":"Konikoff, F.; Jerushalmi, Kuritzky A.; Y, Theodor; E.","year":"1984","unstructured":"Konikoff F, Kuritzky A. Jerushalmi Y, Theodor E. Neuroleptic malignant syndrome induced by a single injection of haloperidol. Br Med J 1984;289:1228-9.","journal-title":"Br Med J"},{"key":"ref_13","first-page":"328","article-title":"Neuroleptic malignant syndrome: physiological and laboratory findings in a series of nine cases","volume":"48","author":"Harsch, H.H.","year":"1987","unstructured":"Harsch HH. Neuroleptic malignant syndrome: physiological and laboratory findings in a series of nine cases. J Clin Psychol 1987;48:328-33.","journal-title":"J Clin Psychol"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1212\/WNL.31.8.1022","article-title":"Neuroleptic malignant syndrome caused by dopamine depleting drugs in a patient with Huntington's chorea","volume":"31","author":"Burke, R.E.; Fahn, S.; Mayeux, R.; Weinberg, H.; Louis, K.; Willner, J.H.","year":"1981","unstructured":"Burke RE, Fahn S, Mayeux R, Weinberg H, Louis K, Willner JH. Neuroleptic malignant syndrome caused by dopamine depleting drugs in a patient with Huntington's chorea. Neurology 1981;31:1022-6.","journal-title":"Neurology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1176\/ajp.141.6.796","article-title":"Case report of neuroleptic malignant syndrome associated with withdrawal of amantadine","volume":"141","author":"Simpson, D.M.; Davis, G.C.","year":"1984","unstructured":"Simpson DM, Davis GC. Case report of neuroleptic malignant syndrome associated with withdrawal of amantadine. Am J Psychiatry 1984;141:796-7.","journal-title":"Am J Psychiatry"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1001\/jama.1985.03360190098033","article-title":"A neuroleptic malignant-like syndrome due to levodopa therapy withdrawal","volume":"254","author":"Friedman, J.H.; Feinberg, S.S.; Feldman, R.G.","year":"1985","unstructured":"Friedman JH, Feinberg SS, Feldman RG. A neuroleptic malignant-like syndrome due to levodopa therapy withdrawal. JAMA 1985;254:2792-5.","journal-title":"JAMA"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1176\/ajp.137.2.254","article-title":"Patients at risk of developing severe side-effects from depot fluphenazine treatment","volume":"137","author":"Blum, A.","year":"1980","unstructured":"Blum A. Patients at risk of developing severe side-effects from depot fluphenazine treatment. Am J Psychiatry 1980;137:254-5.","journal-title":"Am J Psychiatry"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1192\/bjp.146.3.317","article-title":"The aftercare of the patient with neuroleptic malignant syndrome","volume":"146","author":"Aizberg, D.; Shalev, A.; Munitz, H.","year":"1985","unstructured":"Aizberg D, Shalev A, Munitz H. The aftercare of the patient with neuroleptic malignant syndrome. Br J Psychiatry 1985;146: 317-8.","journal-title":"Br J Psychiatry"},{"key":"ref_19","first-page":"445","article-title":"Neuroleptic malignant syndrome","volume":"40","author":"Bhugra, D.K.; Low, N.C.","year":"1986","unstructured":"Bhugra DK, Low NC. Neuroleptic malignant syndrome. Br J Clin Practice 1986;40:445-6.","journal-title":"Br J Clin Practice"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1136\/jnnp.50.4.504","article-title":"Recurrence, hyponatraemia, and neuroleptic malignant syndrome (letter)","volume":"50","author":"Adityanjee","year":"1987","unstructured":"Adityanjee. Recurrence, hyponatraemia, and neuroleptic malignant syndrome (letter). J Neurol, Neurosurg Psychiatry 1987;50:504-5.","journal-title":"J Neurol, Neurosurg Psychiatry"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1192\/bjp.152.4.558","article-title":"Fatal recurrence of neuroleptic malignant syndrome","volume":"152","author":"McCarthy, A.; Bourke, S.; Fahy, J.; Binchy, I.; Fitzgerald, M.X.","year":"1988","unstructured":"McCarthy A, Bourke S, Fahy J, Binchy I, Fitzgerald MX. Fatal recurrence of neuroleptic malignant syndrome. Br J Psychiatry 1988;152:558-9.","journal-title":"Br J Psychiatry"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1212\/WNL.31.2.132","article-title":"Neuroleptic malignant syndrome: a pathogenic role for dopamine receptor blockade","volume":"31","author":"Henderson, V.W.; Wooten, G.F.","year":"1981","unstructured":"Henderson VW, Wooten GF. Neuroleptic malignant syndrome: a pathogenic role for dopamine receptor blockade. Neurology 1981;31:132-7.","journal-title":"Neurology"},{"key":"ref_23","first-page":"4953","article-title":"The neuroleptic malignant syndrome: case report with a review of the literature","volume":"42","author":"Allsop, P.; Twigley, A.J.","year":"1987","unstructured":"Allsop P, Twigley AJ. The neuroleptic malignant syndrome: case report with a review of the literature. Anaesthesia 1987;42:4953.","journal-title":"Anaesthesia"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/BF03259862","article-title":"Aetiology and treatment of neuroleptic malignant syndrome","volume":"2","author":"Harpe, C.; Stoudemire, A.","year":"1987","unstructured":"Harpe C, Stoudemire A. Aetiology and treatment of neuroleptic malignant syndrome. Med Toxicol 1987;2:166-76.","journal-title":"Med Toxicol"},{"key":"ref_25","first-page":"234","article-title":"Neuroleptic malignant syndrome and malignant hyperthermia","volume":"1","author":"Caroff, S.N.; Rosenberg, H.; Gerber, J.C.","year":"1983","unstructured":"Caroff SN, Rosenberg H, Gerber JC. Neuroleptic malignant syndrome and malignant hyperthermia. Lancet 1983;1:234.","journal-title":"Lancet"},{"key":"ref_26","first-page":"565","article-title":"Malignant neuroleptic syndrome its present status in Japan and clinical problems","volume":"31","author":"Itoh, H.; Ohtsuka, N.; Ogita, K.","year":"1977","unstructured":"Itoh H, Ohtsuka N, Ogita K. Malignant neuroleptic syndrome its present status in Japan and clinical problems. Folia Psychiatrica Neurologica (Japan) 1977;31:565-76.","journal-title":"Folia Psychiatrica Neurologica (Japan)"},{"key":"ref_27","first-page":"1183","article-title":"Arch Intern Med","volume":"142","year":"1982","unstructured":"Arch Intern Med 1982;142:1183-5."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1136\/bmj.288.6434.1878","article-title":"Rhabdomyolysis and malignant hyperpyrexia","volume":"1","author":"Denborough, M.A.; Collins, S.P.; Hopkinson, F.C.","year":"1984","unstructured":"Denborough MA, Collins SP, Hopkinson FC. Rhabdomyolysis and malignant hyperpyrexia. Br Med J 1984;1:1878.","journal-title":"Br Med J"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00004714-198208000-00006","article-title":"A case of neuroleptic malignant syndrome: in vitro muscle comparison with malignant hyperthemia","volume":"2","author":"Tollefson, G.","year":"1982","unstructured":"Tollefson G. A case of neuroleptic malignant syndrome: in vitro muscle comparison with malignant hyperthemia. J Clin Psychopharmacol 1982;2:266-70.","journal-title":"J Clin Psychopharmacol"},{"key":"ref_30","first-page":"516","article-title":"Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome. A report of two cases","volume":"33","author":"Goulon, M.; Rohan-Charbot, P.; Elkharrat, D.; Gajdos, P.; Bismith, G.; Conso, F.","year":"1983","unstructured":"Goulon M, Rohan-Charbot P, Elkharrat D, Gajdos P, Bismith G, Conso F. Beneficial effects of dantrolene in the treatment of neuroleptic malignant syndrome. A report of two cases. Neurology 1983;33:516-8.","journal-title":"Neurology"},{"key":"ref_31","first-page":"1350","article-title":"Syndrome malinmortel succedant a une injection d'embl&e d'oenanthate de fluphenazine","volume":"79","author":"Henry, P.; Barat, M.; Bourgeois, M.","year":"1971","unstructured":"Henry P, Barat M, Bourgeois M. Syndrome malinmortel succedant a une injection d'embl&e d'oenanthate de fluphenazine. Presse Med 1971;79:1350.","journal-title":"Presse Med"},{"key":"ref_32","first-page":"126","article-title":"Les hyperthermies dues aux neuroleptiques; essai d'interpretation physiopathologique","volume":"62","author":"Aubert, C.","year":"1973","unstructured":"Aubert C. Les hyperthermies dues aux neuroleptiques; essai d'interpretation physiopathologique. Encephale 1973;62: 126-59.","journal-title":"Encephale"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1176\/ajp.145.5.617","article-title":"Hypothalamic pathology in the neuroleptic malignant syndrome","volume":"145","author":"Horn, E.; Lach, B.; Lapierre, Y.; Hrdina, P.","year":"1988","unstructured":"Horn E, Lach B, Lapierre Y, Hrdina P. Hypothalamic pathology in the neuroleptic malignant syndrome. Am J Psychiatry 1988; 145:617-20.","journal-title":"Am J Psychiatry"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/BF00718024","article-title":"Muscle pathology in the neuroleptic malignant syndrome","volume":"235","author":"Martin, D.; Swash, M.","year":"1987","unstructured":"Martin D, Swash M. Muscle pathology in the neuroleptic malignant syndrome. J Neurol 1987;235:120-1.","journal-title":"J Neurol"},{"key":"ref_35","article-title":"The pathology of malignant hyperpyrexia","volume-title":"Muscle Pathology. U","author":"Harriman, D.","year":"1982","unstructured":"Harriman D. The pathology of malignant hyperpyrexia. In: Mastaglia F, Walton J, eds. Skeletal Muscle Pathology. U.K.: Churchill Livingstone, 1982."}],"container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.52.8.1006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T04:28:35Z","timestamp":1601094515000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.52.8.1006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,8,1]]},"references-count":35,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1989,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.52.8.1006","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1989,8,1]]}}}