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Effect of fludrocortisone and L-threo-3,4-dihydroxyphenylserine on the blood pressure and regional cerebral blood flow."],"prefix":"10.1136","volume":"53","author":[{"given":"S","family":"Matsubara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Sawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Yokoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Takamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"68","article-title":"plasma volume. In this study, it diminished the fall of blood pressure significantly on Faxon D. Mineralocorticoid-induced hypertension in patients with orthostatic hypotension","volume":"301","author":"Chobanian, A.V.; Volicer, L.; Tifft, C.P.; Gavras, H.; Liang, C.-S.","year":"1979","unstructured":"Chobanian AV, Volicer L, Tifft CP, Gavras H, Liang C-S, plasma volume. In this study, it diminished the fall of blood pressure significantly on Faxon D. Mineralocorticoid-induced hypertension in patients with orthostatic hypotension. New Engl J Med 1979;301:68-73. sitting up. It also tended to reduce the fall of rCBF, though the reduction was not statis-","journal-title":"New Engl J Med; reduce the fall of rCBF, though the reduction was not statis"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/BF00605999","article-title":"Pharmacokinetic studies of oral L-threo-3,4-dihydroxyphenylserine in normal subjects and patients with familial amyloid polytically significant. Fludrocortisone may cause various side effects and some of them can be neuropathy","volume":"23","author":"Suzuki, T.; Higa, S.; Sakoda, S.","year":"1982","unstructured":"Suzuki T, Higa S, Sakoda S, et al. Pharmacokinetic studies of oral L-threo-3,4-dihydroxyphenylserine in normal subjects and patients with familial amyloid polytically significant. Fludrocortisone may cause various side effects and some of them can be neuropathy. Eur J Clin Pharmacol 1982;23:463-8.","journal-title":"Eur J Clin Pharmacol"},{"key":"ref_3","first-page":"971","article-title":"Changes in the cerebral blood flow during anaesthesia and surgery in the sitting position","volume":"50","author":"Nelson, R.J.; Lovick, A.H.J.; Pickard, J.D.; Brice, J.; Saunders, D.; Horsey, P.J.","year":"1987","unstructured":"Nelson RJ, Lovick AHJ, Pickard JD, Brice J, Saunders D, Horsey PJ. Changes in the cerebral blood flow during anaesthesia and surgery in the sitting position. J Neurol was the case in the present series. However, DOPS did reduce the fall of the diastolic Neurosurg Psychiatry 1987;50:971-5.","journal-title":"Neurosurg Psychiatry; Neurol was the case in the present series. However, DOPS did reduce the fall of the diastolic"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1212\/WNL.23.3.262","article-title":"Cerebral dysautoregulation in central neurogenic orthostatic blood pressure and of the rCBF significantly on sitting up. hypotension (Shy-Drager syndrome)","volume":"23","author":"Meyer, J.S.; Shimazu, K.; Fukuuchi, Y.","year":"1973","unstructured":"Meyer JS, Shimazu K, Fukuuchi Y, et al. Cerebral dysautoregulation in central neurogenic orthostatic blood pressure and of the rCBF significantly on sitting up. hypotension (Shy-Drager syndrome). Neurology (Minneap) 1973;23:262-73.","journal-title":"Neurology (Minneap)"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1159\/000115093","article-title":"The autoregulation The DOPS is converted into norepinephrine by aromatic L-amino acid decarboxyof cerebral blood flow, the cerebrovascular reactivity and their interaction in the Shy-Drager syndrome","volume":"18","author":"Depresseux, J.C.; Rousseau, J.J.; Franck, G.","year":"1979","unstructured":"Depresseux JC, Rousseau JJ, Franck G. The autoregulation The DOPS is converted into norepinephrine by aromatic L-amino acid decarboxyof cerebral blood flow, the cerebrovascular reactivity and their interaction in the Shy-Drager syndrome. Eur Neurol 1979;18:295-301.","journal-title":"Eur Neurol"},{"key":"ref_6","article-title":"Preservation of autoregulation of cerebral blood flow in autonomic failure","author":"Thomas, D.J.; Bannister, R.","year":"1980","unstructured":"Thomas DJ, Bannister R. Preservation of autoregulation of cerebral blood flow in autonomic failure. J Neurol Sci 1980;44:205-12. supersensitivity to norepinephrine was suggested as an explanation for the pressor res-","journal-title":"J Neurol Sci; 44: 205-12. supersensitivity to norepinephrine was suggested as an explanation for the pressor res"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1136\/jnnp.52.8.962","article-title":"The effect of orthostatic hypotension on cerebral blood flow and middle cerebral artery velocity in autonomic ponse in orthostatic hypotension.3 In a case of Shy-Drager syndrome Kachi et al' demonfailure, with observations on the action of ephedrine","volume":"52","author":"Brooks, D.J.; Redmond, S.; Mathias, C.J.; Bannister, R.; Symon, L.","year":"1989","unstructured":"Brooks DJ, Redmond S, Mathias CJ, Bannister R, Symon L. The effect of orthostatic hypotension on cerebral blood flow and middle cerebral artery velocity in autonomic ponse in orthostatic hypotension.3 In a case of Shy-Drager syndrome Kachi et al' demonfailure, with observations on the action of ephedrine. J Neurol Neurosurg Psychiatry 1989;52:962-6.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_8","first-page":"33","article-title":"The changes in cerebral vascular strated a paucity of muscle sympathetic activity and its increase after administration of DOPS. They suggested that DOPS activates the sympathetic outflow at a site proximal to resistance ofman in experimental alkalosis and acidosis","volume":"32","author":"Schieve, J.F.; Wilson, W.P.","year":"1953","unstructured":"Schieve JF, Wilson WP. The changes in cerebral vascular strated a paucity of muscle sympathetic activity and its increase after administration of DOPS. They suggested that DOPS activates the sympathetic outflow at a site proximal to resistance ofman in experimental alkalosis and acidosis. J Clin Invest 1953;32:33-8.","journal-title":"J Clin Invest"},{"key":"ref_9","first-page":"898","article-title":"Cerebral circulatory and metabolic effects of hypotension produced by deep halothane anaesthesia","volume":"36","author":"Keaney, N.P.; Pickerodt, V.W.; McDowall, D.G.; Coroneos, N.J.; Turner, J.M.; Shah, Z.P.","year":"1973","unstructured":"Keaney NP, Pickerodt VW, McDowall DG, Coroneos NJ, Turner JM, Shah ZP. Cerebral circulatory and metabolic effects of hypotension produced by deep halothane anaesthesia. J Neurol Neurosurg Psychiatry 1973;36:898-905. the sympathetic ganglia. The systemic pressor action of DOPS cer-","journal-title":"J Neurol Neurosurg Psychiatry; the sympathetic ganglia. The systemic pressor action of DOPS cer"},{"key":"ref_10","first-page":"1204","article-title":"Cerebral blood flow and metabolism during drome. Whether DOPS has any effect on the cerebral circulation other than that through isoflurane-induced hypotension in patients subjected to surgery for cerebral aneurysms","volume":"59","author":"Madsen, J.B.; Cold, G.E.; Hansen, E.S.; Bardrum, B.; Kruse-Larsen, C.","year":"1987","unstructured":"Madsen JB, Cold GE, Hansen ES, Bardrum B, Kruse-Larsen C. Cerebral blood flow and metabolism during drome. Whether DOPS has any effect on the cerebral circulation other than that through isoflurane-induced hypotension in patients subjected to surgery for cerebral aneurysms. Br J Anaesthesia 1987; 59:1204-7. the systemic pressor action deserves further discussion. In humans a direct infusion of","journal-title":"Br J Anaesthesia; systemic pressor action deserves further discussion. In humans a direct infusion of"},{"key":"ref_11","first-page":"2373","article-title":"Does mental activity change the oxidative metabolism of the brain?","volume":"7","author":"Roland, P.E.; Eriksson, L.; Stone-Elander, S.; Widen, L.","year":"1987","unstructured":"Roland PE, Eriksson L, Stone-Elander S, Widen L. Does mental activity change the oxidative metabolism of the brain? J Neurosci 1987;7:2373-89. catecholamines into the carotid artery did not change the CBF,22 while in animals intra-","journal-title":"J Neurosci; catecholamines into the carotid artery did not change the CBF,22 while in animals intra"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1001\/archinte.1980.00330200028014","article-title":"Current management concepts in orthostatic hypotension","volume":"140","author":"Schatz, I.J.","year":"1980","unstructured":"Schatz IJ. Current management concepts in orthostatic hypotension. Arch Intern Med 1980;140:1152-4.","journal-title":"Arch Intern Med"},{"key":"ref_13","first-page":"75","article-title":"Effect of L-threo-3,4-dihydroxyphenylserine on regional cerebral blood flow in patients with Parkinson's disease","volume":"83","author":"Ujike, H.; Yamamoto, M.","year":"1988","unstructured":"Ujike H, Yamamoto M. Effect of L-threo-3,4-dihydroxyphenylserine on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Sci 1988;83:75-80. the same action after conversion into the norepinephrine in the cerebral parenchyma.","journal-title":"J Neurol Sci; the same action after conversion into the norepinephrine in the cerebral parenchyma"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0006-2952(68)90158-5","article-title":"The combined use of alpha-methyltyrosine and threodihydroxyphenylserine. Selective reduction of dopamine We thus consider the local action of DOPS in the brain along with the systemic pressor levels in the central nervous system","volume":"17","author":"Creveling, C.R.; Daly, J.; Tokuyama, T.; Witkop, B.","year":"1968","unstructured":"Creveling CR, Daly J, Tokuyama T, Witkop B. The combined use of alpha-methyltyrosine and threodihydroxyphenylserine. Selective reduction of dopamine We thus consider the local action of DOPS in the brain along with the systemic pressor levels in the central nervous system. Biochem Pharmacol 1968;17:65-70.","journal-title":"Biochem Pharmacol"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0006-8993(80)90593-4","article-title":"Cerebral function, metabolic and circulatory effects of intravenous relatively infrequent and are not very severe.28 Our patients experienced none. Because of its infusion of adrenaline in rats","volume":"184","author":"Dahlgren, N.; Rosen, I.; Sakabe, T.; Siesjo, B.K.","year":"1980","unstructured":"Dahlgren N, Rosen I, Sakabe T, Siesjo BK. Cerebral function, metabolic and circulatory effects of intravenous relatively infrequent and are not very severe.28 Our patients experienced none. Because of its infusion of adrenaline in rats. Brain Res 1980;184: 143-52.","journal-title":"Brain Res"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1748-1716.1979.tb06478.x","article-title":"Quantitative changes in regional cerebral effect on blood pressure and rCBF comparable to that of fludrocortisone as well as blood flow of rats induced by alphaand beta-adrenergic stimulants","volume":"107","author":"Edvinsson, L.; Lacombe, P.; Owman, C.H.; Reynier-Rebuffel, A.M.; Seylaz, J.","year":"1979","unstructured":"Edvinsson L, Lacombe P, Owman CH, Reynier-Rebuffel AM, Seylaz J. Quantitative changes in regional cerebral effect on blood pressure and rCBF comparable to that of fludrocortisone as well as blood flow of rats induced by alphaand beta-adrenergic stimulants. Acta Physiol Scand 1979;107:289-96.","journal-title":"Acta Physiol Scand"},{"key":"ref_17","first-page":"824","article-title":"Catecholamines and relatively infrequent and less severe sideeffects, DOPS may well be an alternative the relationship between cerebral blood flow and glucose use","volume":"251","author":"Tuor, U.I.; Edvinsson, L.; McCulloch, J.","year":"1986","unstructured":"Tuor UI, Edvinsson L, McCulloch J. Catecholamines and relatively infrequent and less severe sideeffects, DOPS may well be an alternative the relationship between cerebral blood flow and glucose use. Am J Physiol 1986;251:H824-33.","journal-title":"Am J Physiol"},{"key":"ref_18","first-page":"197","article-title":"choice to fludrocortisone in the treatment of Shy-Drager syndrome. Imura H. Effect of L-threo-3,4-dihydroxyphenylserine (L-DOPS) on catecholamine levels in plasma and cerebrospinal fluid","volume-title":"(CSF) in anesthetized rats. Proc Soc Exp Biol Med","volume":"184","author":"Ishikawa, Y.; Kato, Y.; Murakami, Y.; Inoue, T.; Koshiyama, H.","year":"1987","unstructured":"Ishikawa Y, Kato Y, Murakami Y, Inoue T, Koshiyama H, choice to fludrocortisone in the treatment of Shy-Drager syndrome. Imura H. Effect of L-threo-3,4-dihydroxyphenylserine (L-DOPS) on catecholamine levels in plasma and cerebrospinal fluid (CSF) in anesthetized rats. Proc Soc Exp Biol Med 1987;184:197-200."},{"key":"ref_19","first-page":"593","article-title":"Clinical effects of L-threo-3,4-dihydroxyphenylserine in cases of parkinsonism and pure akinesia","volume":"45","author":"Narabayashi, H.; Kondo, T.; Yokochi, F.; Nagatsu, T.","year":"1986","unstructured":"Narabayashi H, Kondo T, Yokochi F, Nagatsu T. 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