{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:06:26Z","timestamp":1789527986114,"version":"build-2803163510"},"reference-count":29,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"published-print":{"date-parts":[[1993,6,1]]},"DOI":"10.1136\/jnnp.56.6.655","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T22:20:59Z","timestamp":1226355659000},"page":"655-664","source":"Crossref","is-referenced-by-count":65,"title":["High resolution SPECT with [99mTc]-d,l-HMPAO in normal pressure hydrocephalus before and after shunt operation."],"prefix":"10.1136","volume":"56","author":[{"given":"G","family":"Waldemar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J F","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Delecluse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A R","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Gjerris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O B","family":"Paulson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0022-510X(65)90016-X","article-title":"The special clinical problem of symptomatic hydrocephalus with normal cerebrospinalfluid pressure. Observations on cerebrospinal fluid hydrodynamics","volume":"2","author":"Hakim, S.; Adams, R.D.","year":"1965","unstructured":"Hakim S, Adams RD. The special clinical problem of symptomatic hydrocephalus with normal cerebrospinalfluid pressure. Observations on cerebrospinal fluid hydrodynamics. J Neurol Sci 1965;2:307-77.","journal-title":"J Neurol Sci"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1056\/NEJM196507152730301","article-title":"Symptomatic occult hydrocephalus with \"normal\" cerebrospinal fluid pressure","volume":"273","author":"Adams, R.D.; Fischer, C.M.; Hakim, S.; Ojemann, R.G.; Sweet, W.H.","year":"1965","unstructured":"Adams RD, Fischer CM, Hakim S, Ojemann RG, Sweet WH. Symptomatic occult hydrocephalus with \"normal\" cerebrospinal fluid pressure. New Engl Y Med 1965; 273:117-26.","journal-title":"New Engl Y Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"489","DOI":"10.3171\/jns.1979.50.4.0489","article-title":"Intracranial pressure and conductance to outflow of cerebrospinal fluid in normal pressure hydrocephalus","volume":"50","author":"Borgesen, S.E.; Gjerris, F.; S0rensen, S.C.","year":"1979","unstructured":"Borgesen SE, Gjerris F, S0rensen SC. Intracranial pressure and conductance to outflow of cerebrospinal fluid in normal pressure hydrocephalus. J Neurosurg 1979; 50:489-93.","journal-title":"J Neurosurg"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1093\/brain\/105.1.65","article-title":"The predictive value of conductance to outflow of CSF in normal pressure hydrocephalus","volume":"105","author":"Borgesen, S.E.; Gjerris, F.","year":"1982","unstructured":"Borgesen SE, Gjerris F. The predictive value of conductance to outflow of CSF in normal pressure hydrocephalus. Brain 1982;105:65-86.","journal-title":"Brain"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0749-0690(18)30718-3","article-title":"Normal pressure hydrocephalus and dementia-Evaluation and treatment","volume":"4","author":"Turner, D.A.; McGeachie, R.E.","year":"1988","unstructured":"Turner DA, McGeachie RE. Normal pressure hydrocephalus and dementia-Evaluation and treatment. Clinics in Geriatric Medicine 1988;4:815-30.","journal-title":"Clinics in Geriatric Medicine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/archneurpsyc.1942.02290060069004","article-title":"An encephalographic ratio for estimating ventricular enlargement and cerebral atrophy","volume":"47","author":"Evans, W.A.","year":"1942","unstructured":"Evans WA. An encephalographic ratio for estimating ventricular enlargement and cerebral atrophy. Arch Neurol 1942;47:931-7.","journal-title":"Arch Neurol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3171\/jns.1974.41.4.0463","article-title":"Normal-pressure hydrocephalus. Predicting the results of cerebrospinal fluid shunting","volume":"41","author":"Stein, S.C.; Langfitt, T.W.","year":"1974","unstructured":"Stein SC, Langfitt TW. Normal-pressure hydrocephalus. Predicting the results of cerebrospinal fluid shunting. J Neurosurg 1974;41:463-70.","journal-title":"J Neurosurg"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/jcbfm.1991.95","article-title":"99-Tc-d, l-HMPAO and SPECT of the brain in normal aging","volume":"11","author":"Waldemar, G.; Hasselbalch, S.G.; Andersen, A.R.","year":"1991","unstructured":"Waldemar G, Hasselbalch SG, Andersen AR, et al. 99-Tc-d,l-HMPAO and SPECT of the brain in normal aging. J Cereb Blood Flow Metab 1991;11:508-21.","journal-title":"J Cereb Blood Flow Metab"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1192\/bjp.136.3.249","article-title":"Computed tomography in the elederly: I. The normal population","volume":"136","author":"Jacoby, R.J.; Levy, R.; Dawson, J.M.","year":"1980","unstructured":"Jacoby RJ, Levy R, Dawson JM. Computed tomography in the elederly: I. The normal population. Br J Psychiatry 1980;136:249-55.","journal-title":"Br J Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1136\/jnnp.47.12.1314","article-title":"Quantifying cortical atrophy","volume":"47","author":"Turkheimer, E.; Cullum, C.M.; Hubler, D.W.; Paver, S.W.; Yeo, R.A.; Bigler, E.D.","year":"1984","unstructured":"Turkheimer E, Cullum CM, Hubler DW, Paver SW, Yeo RA, Bigler ED. Quantifying cortical atrophy. J Neurol Neurosurg Psychiatry 1984;47: 1314-18.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/00004728-198004000-00022","article-title":"A single photon dynamic computer assisted tomograph (DCAT) for imaging brain function in multiple cross sections","volume":"4","author":"Stokely, E.M.; Sveinsdottir, E.; Lassen, N.A.; Rommer, P.","year":"1980","unstructured":"Stokely EM, Sveinsdottir E, Lassen NA, Rommer P. A single photon dynamic computer assisted tomograph (DCAT) for imaging brain function in multiple cross sections. J Comput Assist Tomogr 1980;4:230-40.","journal-title":"J Comput Assist Tomogr"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/00004728-198110000-00006","article-title":"A method for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations","volume":"5","author":"Celsis, P.; Goldman, T.; Henriksen, L.; Lassen, N.A.","year":"1981","unstructured":"Celsis P, Goldman T, Henriksen L, Lassen NA. A method for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations. J ComputAssist Tomogr 1981;5:641-5.","journal-title":"J ComputAssist Tomogr"},{"key":"ref_13","first-page":"13","article-title":"The retention of [99mTc]-d, l-HMPAO in the human brain after intracarotid bolus injection. A kinetic analysis","volume-title":"Y Cereb Blood Flow Metab","volume":"8","author":"Lassen, N.A.; Andersen, A.R.; Friberg, L.; Paulson, O.B.","year":"1988","unstructured":"Lassen NA, Andersen AR, Friberg L, Paulson OB. The retention of [99mTc]-d,l-HMPAO in the human brain after intracarotid bolus injection. A kinetic analysis. Y Cereb Blood Flow Metab 1988;8:S13-22."},{"key":"ref_14","article-title":"A colour adas of the human brain. Adapted to computed tomography","author":"Aquilonius, S.-M.; Eckernas, S.-A.","year":"1980","unstructured":"Aquilonius S-M, Eckernas S-A. A colour adas of the human brain. Adapted to computed tomography. Stockholm: Esselte Studium, 1980."},{"key":"ref_15","first-page":"13","article-title":"Periventricular hyperintensity as seen by magnetic resonance: Prevalence and significance","volume":"7","author":"Zimmerman, R.D.; Fleming, C.A.; Lee, B.C.P.; Saint-Louis, L.A.; Deck, M.D.F.","year":"1986","unstructured":"Zimmerman RD, Fleming CA, Lee BCP, Saint-Louis LA, Deck MDF. Periventricular hyperintensity as seen by magnetic resonance: Prevalence and significance. AJNR 1986;7:13-20.","journal-title":"AJNR"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1097\/00004728-198711000-00001","article-title":"MR findings in normal-pressure hydrocephalus: significance and comparison with other forms of dementia","volume":"11","author":"Jack, C.R.; Mokri, B.; Laws, E.R.; Houser, O.W.; Baker, H.L.; Petersen, R.C.","year":"1987","unstructured":"Jack CR, Mokri B, Laws ER, Houser OW, Baker HL, Petersen RC. MR findings in normal-pressure hydrocephalus: significance and comparison with other forms of dementia. J Comput Assist Tomogr 1987;11:923-3 1.","journal-title":"J Comput Assist Tomogr"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1001\/archneur.1985.04060090033010","article-title":"Subcortical arteriosclerotic encephalopathy (Binswanger's disease). Computed tomographic, nuclear magnetic resonance, and clinical correlations","volume":"42","author":"Kinkel, W.R.; Jacobs, L.; Polachini, I.; Bates, V.; Heffner, R.R.","year":"1985","unstructured":"Kinkel WR, Jacobs L, Polachini I, Bates V, Heffner RR. Subcortical arteriosclerotic encephalopathy (Binswanger's disease). Computed tomographic, nuclear magnetic resonance, and clinical correlations. Arch Neurol 1985;42:951-9.","journal-title":"Arch Neurol"},{"key":"ref_18","article-title":"Pathophysiology of the CSF circulation","volume-title":"Neurosurgery. The scientific basis of clinical practice","volume":"1","author":"Gjerris, F.; B0rgesen, S.E.","year":"1992","unstructured":"Gjerris F, B0rgesen SE. Pathophysiology of the CSF circulation. In: Crockard A, Hayward R, Hoff JT, eds. Neurosurgery. The scientific basis of clinical practice, vol 1, 2nd ed. Oxford: Blackwell Scientific, 1992.","edition":"2nd ed"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3171\/jns.1987.66.3.0379","article-title":"Cerebral blood flow in patients with normal-pressure hydrocephalus before and after shunting","volume":"66","author":"Vorstrup, S.; Christensen, J.; Gjerris, F.; Sorensen, P.S.; Thomsen, A.M.; Paulson, O.B.","year":"1987","unstructured":"Vorstrup S, Christensen J, Gjerris F, Sorensen PS, Thomsen AM, Paulson OB. Cerebral blood flow in patients with normal-pressure hydrocephalus before and after shunting. J Neurosurg 1987;66:379-87.","journal-title":"J Neurosurg"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF00253445","article-title":"Cortical perfusion assessment with 123I-isopropyl amphetamine (12\"I-IAMP) in normal pressure hydrocephalus (NPH)","volume":"14","author":"Moretti, J.-L.; Sergent, A.; Louarn, F.","year":"1988","unstructured":"Moretti J-L, Sergent A, Louarn F, et al. Cortical perfusion assessment with 123I-isopropyl amphetamine (12\"I-IAMP) in normal pressure hydrocephalus (NPH). Eur J Nucl Med 1988;14:73-79.","journal-title":"Eur J Nucl Med"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1136\/jnnp.50.12.1589","article-title":"Regional cerebral blood flow in normal pressure hydrocephalus","volume":"50","author":"Graff-Radford, N.R.; Rezai, K.; Godersky, J.C.; Eslinger, P.; Damasio, H.; Kirchner, P.T.","year":"1987","unstructured":"Graff-Radford NR, Rezai K, Godersky JC, Eslinger P, Damasio H, Kirchner PT. Regional cerebral blood flow in normal pressure hydrocephalus. J Neurol Neurosurg Psychiatry 1987;50: 1589-96.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1212\/WNL.39.12.1601","article-title":"Variables predicting surgical outcome in symptomatic hydrocephalus in the elderly","volume":"39","author":"Graff-Radford, N.R.; Godersky, J.C.; Jones, M.P.","year":"1989","unstructured":"Graff-Radford NR, Godersky JC, Jones MP. Variables predicting surgical outcome in symptomatic hydrocephalus in the elderly. Neurology 1989;39: 1601-4.","journal-title":"Neurology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/brain\/109.4.613","article-title":"Studies on cerebral oxygen metabolism, blood flow, and blood volume, in patients with hydrocephalus before and after surgical decompression, using positron emission tomography","volume":"109","author":"Brooks, D.J.; Beaney, R.P.; Powell, M.","year":"1986","unstructured":"Brooks DJ, Beaney RP, Powell M, et al. Studies on cerebral oxygen metabolism, blood flow, and blood volume, in patients with hydrocephalus before and after surgical decompression, using positron emission tomography. Brain 1986;109:613-28.","journal-title":"Brain"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1136\/jnnp.48.11.1091","article-title":"Positron emission tomography with ['8F]Fluorodeoxyglucose differentiates normal pressure hydrocephalus from Alzheimer-type dementia","volume":"48","author":"Jagust, W.J.; Friedland, R.P.; Budinger, T.F.","year":"1985","unstructured":"Jagust WJ, Friedland RP, Budinger TF. Positron emission tomography with ['8F]Fluorodeoxyglucose differentiates normal pressure hydrocephalus from Alzheimer-type dementia. J Neurol Neurosurg Psychiatry 1985;48: 1091-6.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_25","first-page":"363","article-title":"Utility of the retained tracer-complex [99mTc]-HMPAO for measurements of regional cerebral blood flow in epilepsy and dementia","volume-title":"work and mental activity","author":"Paulson, O.B.; Andersen, A.R.; Waldemar, G.","year":"1991","unstructured":"Paulson OB, Andersen AR, Waldemar G. Utility of the retained tracer-complex [99mTc]-HMPAO for measurements of regional cerebral blood flow in epilepsy and dementia. In: Lassen NA, Ingvar DH, Raichle ME, Friberg L, eds. Brain work and mental activity. Copenhagen: Munksgaard 1991:363-73."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jnnp.51.3.353","article-title":"Dementia of frontal lobe type","volume":"51","author":"Neary, D.; Snowden, J.S.; Northen, B.; Goulding, P.","year":"1988","unstructured":"Neary D, Snowden JS, Northen B, Goulding P. Dementia of frontal lobe type. J Neurol Neurosurg Psychiatry 1988;51;353-61.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1136\/jnnp.55.11.1018","article-title":"Reduced regional cerebral blood flow in Huntington's disease studied by SPECT","volume":"55","author":"true","year":"1992","unstructured":"Hasselbalch SG, 0berg G, S0rensen SA, et al. Reduced regional cerebral blood flow in Huntington's disease studied by SPECT. J Neurol Neurosurg Psychiatry 1992; 55:1018-23.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/jcbfm.1988.35","article-title":"Quantitative measurements of cerebral blood flow using SPECT and [\"mTc]-d, l-HMPAO compared to xenon133","volume":"8","author":"Andersen, A.R.; Friberg, H.H.; Schmidt, J.F.; Hasselbalch, S.G.","year":"1988","unstructured":"Andersen AR, Friberg HH, Schmidt JF, Hasselbalch SG. Quantitative measurements of cerebral blood flow using SPECT and [\"mTc]-d,l-HMPAO compared to xenon133. J Cereb Blood Flow Metab 1988;8:S69-81.","journal-title":"J Cereb Blood Flow Metab"},{"key":"ref_29","first-page":"80","article-title":"SPECT in the presurgical evaluation of patients with temporal lobe epilepsy-a preliminary report","volume":"50","author":"Andersen, A.R.; Waldemar, G.; Dam, M.; FugisangFrederiksen, A.; Herning, M.; Kruse-Larsen, C.","year":"1990","unstructured":"Andersen AR, Waldemar G, Dam M, FugisangFrederiksen A, Herning M, Kruse-Larsen C. SPECT in the presurgical evaluation of patients with temporal lobe epilepsy-a preliminary report. Acta Neurochir 1990;Suppl 50:80-83.","journal-title":"Acta Neurochir"}],"container-title":["Journal of Neurology, Neurosurgery &amp; Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.56.6.655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T10:08:41Z","timestamp":1632132521000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.56.6.655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,6,1]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1993,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.56.6.655","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1993,6,1]]}}}