{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T09:50:08Z","timestamp":1789725008069,"version":"4.0.1"},"reference-count":46,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"published-print":{"date-parts":[[1995,9,1]]},"DOI":"10.1136\/jnnp.59.3.299","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T22:20:59Z","timestamp":1226355659000},"page":"299-302","source":"Crossref","is-referenced-by-count":105,"title":["Cardiovascular tests of autonomic function and sympathetic skin responses in patients with major depression."],"prefix":"10.1136","volume":"59","author":[{"given":"S M","family":"Guinjoan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J L","family":"Bernabo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D P","family":"Cardinali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"44","article-title":"Manic-depressive insanity and paranoia","author":"Kraepelin, E.","year":"1921","unstructured":"Kraepelin E. Manic-depressive insanity and paranoia. Edinburgh: Livingstone, 1921:44-53."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000286013","article-title":"The relationship of myocardial infarction to depressive illness","volume":"17","author":"Dreyfuss, F.; Dasberg, H.; Assael, M.I.","year":"1969","unstructured":"Dreyfuss F, Dasberg H, Assael MI. The relationship of myocardial infarction to depressive illness. Psychother Psychosom 1969;17:73-81.","journal-title":"Psychother Psychosom"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/j.1469-8986.1977.tb01201.x","article-title":"Autonomic correlates of depression and clinical improvement following electroconvulsive shock therapy","volume":"14","author":"Dawson, M.E.; Schell, A.M.; Catania, J.J.","year":"1977","unstructured":"Dawson ME, Schell AM, Catania JJ. Autonomic correlates of depression and clinical improvement following electroconvulsive shock therapy. Psychophysiology 1977;14: 569-78.","journal-title":"Psychophysiology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000119168","article-title":"Correlation between skin potential response and psychopathology in patients with affective disorders","volume":"31","author":"Guinjoan, S.M.; Bonanni Rey, R.A.; Cardinali, D.P.","year":"1995","unstructured":"Guinjoan SM, Bonanni Rey RA, Cardinali DP. Correlation between skin potential response and psychopathology in patients with affective disorders. Neuropsychobiology 1995;31:24-30.","journal-title":"Neuropsychobiology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1001\/archpsyc.1980.01780220017001","article-title":"Premature deaths in schizophrenia and affective disorders. An analysis of survival curves and variables affecting the shortened survival","volume":"37","author":"Tsuang, M.T.; Woolson, K.F.; Flemming, J.A.","year":"1980","unstructured":"Tsuang MT, Woolson KF, Flemming JA. Premature deaths in schizophrenia and affective disorders. An analysis of survival curves and variables affecting the shortened survival. Arch Gen Psychiatry 1980;37:979-83.","journal-title":"Arch Gen Psychiatry"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0165-0327(85)90096-5","article-title":"High fatality rates of late life depression associated with cardiovascular disease","volume":"9","author":"Rabins, P.V.; Harvis, K.; Koven, S.","year":"1985","unstructured":"Rabins PV, Harvis K, Koven S. High fatality rates of late life depression associated with cardiovascular disease. J Affect Disord 1985;9: 165-7.","journal-title":"J Affect Disord"},{"key":"ref_7","first-page":"252","article-title":"Decreased heart rate variability and its association with mortality after myocardial infarction","volume":"59","author":"Kleiger, R.E.; Miller, J.P.; Bigger, J.T.; Moss, A.J.","year":"1987","unstructured":"Kleiger RE, Miller JP, Bigger JT, Moss AJ. Decreased heart rate variability and its association with mortality after myocardial infarction. Am J Cardiol 1987;59: 252-6.","journal-title":"Am J Cardiol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1109\/TBME.1986.325694","article-title":"Power spectral analysis of heart rate variability in sudden cardiac death: comparison to other methods","volume":"33","author":"Myers, G.A.; Martin, G.J.; Magid, N.M.","year":"1986","unstructured":"Myers GA, Martin GJ, Magid NM. Power spectral analysis of heart rate variability in sudden cardiac death: comparison to other methods. IEEE Trans Biomed Eng 1986;33: 1149-56.","journal-title":"IEEE Trans Biomed Eng"},{"key":"ref_9","first-page":"730","article-title":"Emotional response and clinical severity as early determinants of six-month mortality after myocardial infarction","volume-title":"Heart Lung","volume":"4","author":"Garrity, T.F.; Klein, R.F.","year":"1975","unstructured":"Garrity TF, Klein RF. Emotional response and clinical severity as early determinants of six-month mortality after myocardial infarction. Heart Lung 1975;4:730-7."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1192\/bjp.152.1.34","article-title":"Growth hormone response to clonidine after recovery in patients with endogenous depression","volume":"152","author":"Mitchell, P.B.; Beam, J.A.; Corn, T.H.; Checkley, S.A.","year":"1988","unstructured":"Mitchell PB, Beam JA, Corn TH, Checkley SA. Growth hormone response to clonidine after recovery in patients with endogenous depression. Br J Psychiatry 1988;152: 34-8.","journal-title":"Br J Psychiatry"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/ana.410210502","article-title":"Disorders of the autonomic nervous system: Part 1. Pathophysiology and clinical features","volume":"21","author":"McLeod, J.G.; Tuck, R.R.","year":"1987","unstructured":"McLeod JG, Tuck RR. Disorders of the autonomic nervous system: Part 1. Pathophysiology and clinical features. Ann Neurol 1987;21:419-30.","journal-title":"Ann Neurol"},{"key":"ref_12","first-page":"231","article-title":"The role of the sympathetic skin response in the assessment of autonomic function","volume-title":"Clinical Autonomic Disorders","author":"Schondorf, R.","year":"1993","unstructured":"Schondorf R. The role of the sympathetic skin response in the assessment of autonomic function. In: Low PA, ed. Clinical Autonomic Disorders. Boston: Little, Brown and Co, 1993:231-41."},{"key":"ref_13","article-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association. DSM-III-R","year":"1987","unstructured":"American Psychiatric Association. DSM-III-R: Diagnostic and statistical manual of mental disorders. 3rd ed revised. Washington DC: APA, 1987.","edition":"3rd ed revised"},{"key":"ref_14","first-page":"662","article-title":"Psychopathology in patients with Wilson's disease. Am 7Psychiatry 1989; 146","unstructured":"Medalia A, Scheinberg MD. Psychopathology in patients with Wilson's disease. Am 7Psychiatry 1989;146:662-4."},{"key":"ref_15","first-page":"345","article-title":"Development of an autonomic laboratory","volume-title":"Clinical autonomic disorders","author":"Low, P.A.; Zimmerman, I.R.","year":"1993","unstructured":"Low PA, Zimmerman IR. Development of an autonomic laboratory. In: Low PA, ed. Clinical autonomic disorders. Boston: Little, Brown and Co, 1993:345-54."},{"key":"ref_16","article-title":"Pitfalls in autonomic testing","volume-title":"Clinical autonomic disorders","author":"Low, P.A.","unstructured":"Low PA. Pitfalls in autonomic testing. In: Low PA, ed. Clinical autonomic disorders. Boston: Little, Brown and Co, 1993:363."},{"key":"ref_17","article-title":"Standardization of clinical tests for practice and clinical trials","volume-title":"Clinical autonomic disorders","author":"Low, P.A.; Pfeifer, M.A.","unstructured":"Low PA, Pfeifer MA. Standardization of clinical tests for practice and clinical trials. In: Low PA, ed. Clinical autonomic disorders. Boston: Little, Brown and Co, 1993:294."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.1.6168.924","article-title":"Respiratory influence on heart rate in diabetes mellitus","volume":"1","author":"Sundkvist, G.; Almer, L.-O.; Lilja, B.","year":"1979","unstructured":"Sundkvist G, Almer L-O, Lilja B. Respiratory influence on heart rate in diabetes mellitus. BM,J 1979;1:924-5.","journal-title":"BM, J"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0002-9149(66)90200-1","article-title":"A simple test of cardiac function based upon the heart rate changes induced by the Valsalva manoeuvre","volume":"18","author":"Levin, A.B.","year":"1966","unstructured":"Levin AB. A simple test of cardiac function based upon the heart rate changes induced by the Valsalva manoeuvre. Am J Cardiol 1966;18:90-9.","journal-title":"Am J Cardiol"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2337\/diacare.8.5.491","article-title":"The value of cardiovascular autonomic function tests: 10 years experience in diabetes","volume":"8","author":"Ewing, D.J.; Martyn, C.N.; Young, R.J.; Clarke, B.F.","year":"1985","unstructured":"Ewing DJ, Martyn CN, Young RJ, Clarke BF. The value of cardiovascular autonomic function tests: 10 years experience in diabetes. Diabetes Care 1985;8:491-8.","journal-title":"Diabetes Care"},{"key":"ref_21","first-page":"295","article-title":"Cardiovascular responses to sustained handgrip in normal subjects and in patients with diabetes mellitus: a test of autonomic function","volume":"46","author":"Ewing, D.J.; Irving, J.B.; Kerr, F.","year":"1974","unstructured":"Ewing DJ, Irving JB, Kerr F. Cardiovascular responses to sustained handgrip in normal subjects and in patients with diabetes mellitus: a test of autonomic function. Clin Sci Mol Med 1974;46:295-306.","journal-title":"Clin Sci Mol Med"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0002-8703(36)90370-8","article-title":"The cold pressor test for measuring the reactivity of the blood pressure: data concerning 571 normal and hypertensive subjects","volume":"11","author":"Hines, E.A.; Brown, G.E.","year":"1936","unstructured":"Hines EA, Brown GE. The cold pressor test for measuring the reactivity of the blood pressure: data concerning 571 normal and hypertensive subjects. Am Heart J 1936;11: 1-9.","journal-title":"Am Heart J"},{"key":"ref_23","first-page":"67","article-title":"Effects of mental arithmetic on arterial pressure and hand blood flow. Clin Exp Pharmacol Physiol suppl","volume":"2","author":"Ludbrook, J.; Vincent, A.; Walsh, J.A.","year":"1975","unstructured":"Ludbrook J, Vincent A, Walsh JA. Effects of mental arithmetic on arterial pressure and hand blood flow. Clin Exp Pharmacol Physiol suppl 1975;2:67-70."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.2337\/diab.27.12.1167","article-title":"Assessment of methods for estimating autonomic nervous control of the heart in patients with diabetes mellitus","volume":"27","author":"Bennett, T.; Farquhar, J.K.; Hosking, D.J.; Hampton, JR","year":"1978","unstructured":"Bennett T, Farquhar JK, Hosking DJ, Hampton JR. Assessment of methods for estimating autonomic nervous control of the heart in patients with diabetes mellitus. Diabetes 1978;27:1167-74.","journal-title":"Diabetes"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1136\/jnnp.47.5.536","article-title":"Sympathetic skin response-a method of assessing unmyelinated axon dysfunction in peripheral neuropathies","volume":"47","author":"Shahani, B.T.; Halperin, J.J.; Boulu, P.; Cohen, J.","year":"1984","unstructured":"Shahani BT, Halperin JJ, Boulu P, Cohen J. Sympathetic skin response-a method of assessing unmyelinated axon dysfunction in peripheral neuropathies. Jf Neurol Neurosurg Psychiatry 1984;47:536-42.","journal-title":"Jf Neurol Neurosurg Psychiatry"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/BF01713056","article-title":"Autonomic function tests as related to age and gender in normal man","volume":"64","author":"Gautschy, B.; Weidmann, P.; Gnadinger, M.P.","year":"1986","unstructured":"Gautschy B, Weidmann P, Gnadinger MP. Autonomic function tests as related to age and gender in normal man. Klinische Wochenschrift (Berlin) 1986;64:499-505.","journal-title":"Klinische Wochenschrift (Berlin)"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/brain\/98.3.341","article-title":"The sympathetic nervous system in diabetic neuropathy-a clinical and pathological study","volume":"98","author":"Low, P.A.; Walsh, J.C.; Huang, C.-Y.; MacLeod, J.G.","year":"1975","unstructured":"Low PA, Walsh JC, Huang C-Y, MacLeod JG. The sympathetic nervous system in diabetic neuropathy-a clinical and pathological study. Brain 1975;98:341-56.","journal-title":"Brain"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"308","DOI":"10.7326\/0003-4819-92-2-308","article-title":"Assessment of cardiovascular effects in diabetic autonomic neuropathy and prognostic implications","volume":"92","author":"Ewing, D.J.; Campbell, I.W.; Clarke, B.F.","year":"1980","unstructured":"Ewing DJ, Campbell IW, Clarke BF. Assessment of cardiovascular effects in diabetic autonomic neuropathy and prognostic implications. Ann Intern Med 1980;92: 308-11.","journal-title":"Ann Intern Med"},{"key":"ref_29","first-page":"583","article-title":"Evaluation of skin vasomotor reflexes by using laser Doppler velocimetry","volume-title":"Mayo Clin Proc 1983; 58","author":"Low, P.A.; Neumann, C.; Dyck, P.J.; Fealey, R.D.; Tuck, R.R.","unstructured":"Low PA, Neumann C, Dyck PJ, Fealey RD, Tuck RR. Evaluation of skin vasomotor reflexes by using laser Doppler velocimetry. Mayo Clin Proc 1983;58:583-92."},{"key":"ref_30","first-page":"1053","article-title":"Evidence of vagal neuropathy in chronic alcoholics","volume":"ii:","author":"Duncan, G.; Johnson, R.H.; Lambie, D.G.; Whiteside, E.A.","year":"1980","unstructured":"Duncan G, Johnson RH, Lambie DG, Whiteside EA. Evidence of vagal neuropathy in chronic alcoholics. Lancet 1980;ii: 1053-7.","journal-title":"Lancet"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1136\/jnnp.48.10.1025","article-title":"Autonomic neuropathy in acute intermittent porphyria","volume":"48","author":"AAC, Yeung Laiwah; R, Mactier; KEL, McColl; MR, Moore; A, Goldberg","year":"1985","unstructured":"Yeung Laiwah AAC, Mactier R, McColl KEL, Moore MR, Goldberg A. Autonomic neuropathy in acute intermittent porphyria. 7 Neurol Neurosurg Psychiatry 1985; 48:1025-30.","journal-title":"7 Neurol Neurosurg Psychiatry"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/brain\/102.1.163","article-title":"Defective cardiovascular reflexes and supersensitivity to sympathomimetic drugs in autonomic failure","volume":"102","author":"Bannister, R.","year":"1979","unstructured":"Bannister R. Defective cardiovascular reflexes and supersensitivity to sympathomimetic drugs in autonomic failure. Brain 1979;102:163-76.","journal-title":"Brain"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/mus.880110311","article-title":"Sympathetic skin response in diabetic peripheral neuropathy","volume":"11","author":"Niakan, E.; Harati, Y.","year":"1988","unstructured":"Niakan E, Harati Y. Sympathetic skin response in diabetic peripheral neuropathy. Muscle Nerve 1988;11:261-4.","journal-title":"Muscle Nerve"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/mus.880120513","article-title":"Comparison of sympathetic skin response with quantitative sudomotor axon reflex test in diabetic neuropathy","volume":"12","author":"Maselli, R.A.; Jaspan, J.B.; Soliven, B.C.; Green, A.J.; Spire, J.-P.; Arnason, B.G.W.","year":"1989","unstructured":"Maselli RA, Jaspan JB, Soliven BC, Green AJ, Spire J-P, Arnason BGW. Comparison of sympathetic skin response with quantitative sudomotor axon reflex test in diabetic neuropathy. Muscle Nerve 1989;12:420-3.","journal-title":"Muscle Nerve"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1093\/brain\/114.3.1381","article-title":"Sympathetic skin response in patients with multiple sclerosis compared with patients with spinal cord transection and normal controls","volume":"114","author":"Yokota, T.; Matsunaga, T.; Okiyama, R.","year":"1991","unstructured":"Yokota T, Matsunaga T, Okiyama R, et al. Sympathetic skin response in patients with multiple sclerosis compared with patients with spinal cord transection and normal controls. Brain 1991;114:1381-94.","journal-title":"Brain"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1002\/mus.880160907","article-title":"Sympathetic skin response abnormalities in amyotrophic lateral sclerosis","volume":"16","author":"Dettmers, C.; Fatepour, D.; Faust, H.; Jerusalem, F.","year":"1993","unstructured":"Dettmers C, Fatepour D, Faust H, Jerusalem F. Sympathetic skin response abnormalities in amyotrophic lateral sclerosis. Muscle Nerve 1993;16:930-4.","journal-title":"Muscle Nerve"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0140-6736(60)92773-2","article-title":"Absent circulatory reflexes in diabetic neuritis","volume":"i:","author":"Sharpey-Schafer, E.P.; Taylor, D.J.","year":"1960","unstructured":"Sharpey-Schafer EP, Taylor DJ. Absent circulatory reflexes in diabetic neuritis. Lancet 1960;i:559-62.","journal-title":"Lancet"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1176\/ajp.139.10.1315","article-title":"High plasma norepinephrine levels in patients with major affective disorder","volume":"139","author":"Lake, C.R.; Pickar, D.; Ziegler, M.G.; Lipper, S.; Slater, S.; Murphy, D.L.","year":"1982","unstructured":"Lake CR, Pickar D, Ziegler MG, Lipper S, Slater S, Murphy DL. High plasma norepinephrine levels in patients with major affective disorder. Am J Psychiatry 1982;139:1315-8.","journal-title":"Am J Psychiatry"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0022-3956(87)90004-5","article-title":"Cardiac regulation and depression","volume":"21","author":"Lahmeyer, H.W.; Bellier, S.N.","year":"1987","unstructured":"Lahmeyer HW, Bellier SN. Cardiac regulation and depression. J Psychiatr Res 1987;21:1-6.","journal-title":"J Psychiatr Res"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0022-3999(88)90050-5","article-title":"The relationship between heart rate, heart rate variability and depression in patients with coronary artery disease","volume":"32","author":"Carney, R.M.; Rich, M.W.; teVelde A; Saini, J.; Clark, K.; Freedland, K.E.","year":"1988","unstructured":"Carney RM, Rich MW, teVelde A, Saini J, Clark K, Freedland KE. The relationship between heart rate, heart rate variability and depression in patients with coronary artery disease. J Psychosom Res 1988;32: 159-64.","journal-title":"J Psychosom Res"},{"key":"ref_41","first-page":"4","article-title":"Perspectives on the relationship between cardiovascular disease and affective disorder..7 Clin","volume":"51","author":"Dalack, G.W.; Roose, S.P.","year":"1990","unstructured":"Dalack GW, Roose SP. Perspectives on the relationship between cardiovascular disease and affective disorder..7 Clin Psychiatry 1990;51 (suppl):4-9.","journal-title":"Psychiatry"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0165-1781(91)90104-W","article-title":"Heart rate variability in patients with major depression","volume":"37","author":"Yeragani, V.K.; Pohl, R.; Balon, R.; Ramesh, C.; Glitz, D.; Jung, I.; Sherwood, P.","year":"1991","unstructured":"Yeragani VK, Pohl R, Balon R, Ramesh C, Glitz D, Jung I, Sherwood P. Heart rate variability in patients with major depression. Psychiatry Res 1991;37:35-46.","journal-title":"Psychiatry Res"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1748-1716.1972.tb05167.x","article-title":"General characteristics of sympathetic activity in human skin nerves","volume":"84","author":"Hagbarth, K.-E.; Hallin, R.G.; Hongell, A.; Thorebjork, H.E.; Wallin, B.G.","year":"1972","unstructured":"Hagbarth K-E, Hallin RG, Hongell A, Thorebjork HE, Wallin BG. General characteristics of sympathetic activity in human skin nerves. Acta Physiol Scand 1972;84: 164-76.","journal-title":"Acta Physiol Scand"},{"key":"ref_44","first-page":"239","article-title":"Peripheral autonomic surface potential: a quantitative technique for recording sympathetic conduction in man..7 Neurol","volume":"67","author":"Knezevic, W.; Bajada, S.","year":"1985","unstructured":"Knezevic W, Bajada S. Peripheral autonomic surface potential: a quantitative technique for recording sympathetic conduction in man..7 Neurol Sci 1985;67:239-5 1.","journal-title":"Sci"},{"key":"ref_45","article-title":"The autonomic nervous system","author":"0, Appenzeller","year":"1990","unstructured":"Appenzeller 0. The autonomic nervous system. Amsterdam: Elsevier, 1990."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/ddr.430040202","article-title":"Cholinomimetic and anticholinergic drugs used to investigate an acetylcholine hypothesis of affective disorders and stress","volume":"4","author":"Janowsky, D.S.; Risch, S.C.","year":"1984","unstructured":"Janowsky DS, Risch SC. Cholinomimetic and anticholinergic drugs used to investigate an acetylcholine hypothesis of affective disorders and stress. Drug Development Research 1984;4: 125-42.","journal-title":"Drug Development Research"}],"container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.59.3.299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T02:50:50Z","timestamp":1601088650000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.59.3.299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9,1]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.59.3.299","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1995,9,1]]}}}