{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:39:58Z","timestamp":1791329998245,"version":"4.3.1"},"reference-count":15,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"published-print":{"date-parts":[[1996,9,1]]},"DOI":"10.1136\/jnnp.61.3.314","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T22:20:59Z","timestamp":1226355659000},"page":"314-317","source":"Crossref","is-referenced-by-count":44,"title":["Brain and spinal cord MRI in motor neuron disease."],"prefix":"10.1136","volume":"61","author":[{"given":"J W","family":"Thorpe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I F","family":"Moseley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C H","family":"Hawkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D G","family":"MacManus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W I","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D H","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/ana.410230424","article-title":"Magnetic resonance imaging in amyotrophic lateral sclerosis","volume":"23","author":"Goodin, D.S.; Rowley, H.A.; Olney, R.K.","year":"1988","unstructured":"Goodin DS, Rowley HA, Olney RK. Magnetic resonance imaging in amyotrophic lateral sclerosis. Ann Neurol 1988;23:418-20.","journal-title":"Ann Neurol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/BF00314764","article-title":"Magnetic resonance imaging in motor neuron disease","volume":"237","author":"ML, Sales Luis; A, Hormigo; C, Mauricio; MM, Alves; R, Serrao","year":"1990","unstructured":"Sales Luis ML, Hormigo A, Mauricio C, Alves MM, Serrao R. Magnetic resonance imaging in motor neuron disease. Jf Neurol 1990;237:471-4.","journal-title":"Jf Neurol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1212\/WNL.43.8.1569","article-title":"Single-photon emission computed tomographic investigation of patients with motor neuron disease","volume":"43","author":"Abe, K.; Fujimura, H.; Toyooka, K.","year":"1993","unstructured":"Abe K, Fujimura H, Toyooka K, et al. Single-photon emission computed tomographic investigation of patients with motor neuron disease. Neurology 1993;43:1569-73.","journal-title":"Neurology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/brain\/115.2.495","article-title":"Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria","volume":"115","author":"Pringle, C.E.; Hudson, A.J.; Munoz, D.G.; Kieman, J.A.; Brown, W.F.; Ebers, G.C.","year":"1992","unstructured":"Pringle CE, Hudson AJ, Munoz DG, Kieman JA, Brown WF, Ebers GC. Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria. Brain 1992;115:495-520.","journal-title":"Brain"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/ana.410330214","article-title":"Signal loss in the motor cortex on magnetic resonance images in amyotrophic lateral sclerosis","volume":"33","author":"Ishikawa, K.; Nagura, H.; Yokota, T.; Yamanouchi, H.","year":"1993","unstructured":"Ishikawa K, Nagura H, Yokota T, Yamanouchi H. Signal loss in the motor cortex on magnetic resonance images in amyotrophic lateral sclerosis. Ann Neurol 1993;33: 218-22.","journal-title":"Ann Neurol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"604","DOI":"10.2214\/ajr.160.3.8430564","article-title":"Amyotrophic lateral sclerosis: hyperintensity of the corticospinal tracts on MR images of the spinal cord","volume":"160","author":"Friedman, D.P.; Tartaglino, L.S.","year":"1993","unstructured":"Friedman DP, Tartaglino LS. Amyotrophic lateral sclerosis: hyperintensity of the corticospinal tracts on MR images of the spinal cord. AJR Am Jf Roentgenol 1993; 160:604-6.","journal-title":"AJR Am Jf Roentgenol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1212\/WNL.40.11.1799","article-title":"Selective involvement of the pyramidal tract on magnetic resonance imaging in primary lateral sclerosis","volume":"40","author":"Marti-Fabregas, J.; Pujol, J.","year":"1990","unstructured":"Marti-Fabregas J, Pujol J. Selective involvement of the pyramidal tract on magnetic resonance imaging in primary lateral sclerosis. Neurology 1990;40: 1799-800.","journal-title":"Neurology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/BF00862986","article-title":"MRI lesions in motor neuron disease","volume":"239","author":"Iwasaki, Y.; Ikeda, K.; Kinoshita, M.","year":"1992","unstructured":"Iwasaki Y, Ikeda K, Kinoshita M. MRI lesions in motor neuron disease. Jf Neurol 1992;239:112-3.","journal-title":"Jf Neurol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1001\/archneurpsyc.1941.02280240094006","article-title":"Amyotrophic lateral sclerosis. Origin and extent of upper motor neuron lesion","volume":"46","author":"Davison, C.","year":"1941","unstructured":"Davison C. Amyotrophic lateral sclerosis. Origin and extent of upper motor neuron lesion. Arch Neurol Psych 1941;46: 1039-56.","journal-title":"Arch Neurol Psych"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1001\/archneurpsyc.1953.02320260029002","article-title":"Amyotrophic lateral sclerosis. A clinicoanatomic study of fifty-three cases","volume":"69","author":"Lawyer, T.; Netsky, M.G.","year":"1953","unstructured":"Lawyer T, Netsky MG. Amyotrophic lateral sclerosis. A clinicoanatomic study of fifty-three cases. Arch Neurol Psych 1953;69:171-92.","journal-title":"Arch Neurol Psych"},{"issue":"23","key":"ref_11","first-page":"269","article-title":"Nerve fibre degeneration in the brain in amyotrophic lateral sclerosis","volume":"1960","author":"Smith, M.C.","unstructured":"Smith MC. Nerve fibre degeneration in the brain in amyotrophic lateral sclerosis. Jf Neurol Neurosurg Psychiatry 1960;23:269-82.","journal-title":"Jf Neurol Neurosurg Psychiatry"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1136\/jnnp.33.3.338","article-title":"The central nervous system in motor neurone disease","volume":"33","author":"Brownell, B.; Oppenheimer, D.R.; Hughes, T.J.","year":"1970","unstructured":"Brownell B, Oppenheimer DR, Hughes TJ. The central nervous system in motor neurone disease. J Neurol Neurosurg Psychiatry 1970;33:338-57.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1148\/radiology.172.2.2748836","article-title":"Focal signalintensity variations in the posterior internal capsule: normal MR findings and distinction from pathologic findings","volume":"172","author":"Mirowitz, S.; Sartor, K.; Gado, M.; Torack, R.","year":"1989","unstructured":"Mirowitz S, Sartor K, Gado M, Torack R. Focal signalintensity variations in the posterior internal capsule: normal MR findings and distinction from pathologic findings. Radiology 1989;172:535-9.","journal-title":"Radiology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1212\/WNL.42.8.1641","article-title":"MRI in ALS","volume":"42","author":"Oberwittler, C.; Ludolf, A.C.; Masur, H.; Fahrendorf, G.","year":"1992","unstructured":"Oberwittler C, Ludolf AC, Masur H, Fahrendorf G. MRI in ALS [letter]. Neurology 1992;42: 1641.","journal-title":"Neurology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1097\/00004728-199207000-00002","article-title":"High signal regions in normal white matter shown by heavily T2weighted CSF nulled IR sequences","volume":"16","author":"Hajnal, J.V.; De Coene, B.; Lewis, P.D.","year":"1992","unstructured":"Hajnal JV, De Coene B, Lewis PD, et al. High signal regions in normal white matter shown by heavily T2weighted CSF nulled IR sequences. Jf Comput Assist Tomogr 1992;16:506-13.","journal-title":"Jf Comput Assist Tomogr"}],"container-title":["Journal of Neurology, Neurosurgery & Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jnnp.61.3.314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T02:54:12Z","timestamp":1601088852000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnnp.bmj.com\/lookup\/doi\/10.1136\/jnnp.61.3.314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,9,1]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/jnnp.61.3.314","relation":{},"ISSN":["0022-3050"],"issn-type":[{"value":"0022-3050","type":"print"}],"subject":[],"published":{"date-parts":[[1996,9,1]]}}}