{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T20:40:03Z","timestamp":1774384803089,"version":"3.50.1"},"reference-count":16,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J Med Ethics"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Uterus transplantation is an emerging technology adding to the arsenal of treatments for infertility; specifically the only available treatment for uterine factor infertility. Ethical investigations concerning risks to uteri donors and transplant recipients have been discussed in the literature. However, missing from the discourse is the potential of uterus transplantation in other groups of genetically XY women who experience uterine factor infertility. There have been philosophical inquiries concerning uterus transplantation in genetically XY women, which includes transgender women and women with complete androgen insufficiency syndrome. We discuss the potential medical steps necessary and associated risks for uterus transplantation in genetically XY women. Presently, the medical technology does not exist to make uterus transplantation a safe and effective option for genetically XY women, however this group should not be summarily excluded from participation in trials. Laboratory research is needed to better understand and reduce medical risk and widen the field to all women who face uterine factor infertility.<\/jats:p>","DOI":"10.1136\/medethics-2018-105222","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T22:25:29Z","timestamp":1551133529000},"page":"687-689","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Uterus transplantation in women who are genetically XY"],"prefix":"10.1136","volume":"45","author":[{"given":"Amani","family":"Sampson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura L.","family":"Kimberly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara N.","family":"Goldman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Keefe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwendolyn P.","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,2,25]]},"reference":[{"key":"2020050722471641000_45.10.687.1","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1055\/s-0037-1606321","article-title":"What are the possibilities of uterine transplantation in transgender patients?","volume":"39","author":"Lerner","year":"2017","journal-title":"Rev Bras Ginecol Obstet"},{"key":"2020050722471641000_45.10.687.2","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jogoh.2018.03.006","article-title":"Uterine transplantation: Review in human research","volume":"47","author":"Favre-Inhofer","year":"2018","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"2020050722471641000_45.10.687.3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MOT.0000000000000568","article-title":"Current status and future direction of uterus transplantation","volume":"23","author":"Br\u00e4nnstr\u00f6m","year":"2018","journal-title":"Curr Opin Organ Transplant"},{"key":"2020050722471641000_45.10.687.4","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1016\/S0140-6736(18)31766-5","article-title":"Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility","volume":"392","author":"Ejzenberg","year":"2019","journal-title":"Lancet"},{"key":"2020050722471641000_45.10.687.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2012.01438.x"},{"key":"2020050722471641000_45.10.687.6","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.fertnstert.2018.06.017","article-title":"American Society for Reproductive Medicine position statement on uterus transplantation: a committee opinion","volume":"110","author":"Practice Committee of the American Society for Reproductive Medicine","year":"2018","journal-title":"Fertil Steril"},{"key":"2020050722471641000_45.10.687.7","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0140-6736(12)60071-3","article-title":"Androgen insensitivity syndrome","volume":"380","author":"Hughes","year":"2012","journal-title":"The Lancet"},{"key":"2020050722471641000_45.10.687.8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ejogrb.2016.08.027","article-title":"Uterus transplantation in France: for which patients?","volume":"205","author":"Huet","year":"2016","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2020050722471641000_45.10.687.9","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.135.1.14"},{"key":"2020050722471641000_45.10.687.10","unstructured":"Ethics-ISUTx. 2018. http:\/\/www.isutx.org\/ethics\/ (accessed 29 Aug 2018)."},{"key":"2020050722471641000_45.10.687.11","doi-asserted-by":"publisher","DOI":"10.1111\/and.12150"},{"key":"2020050722471641000_45.10.687.12","doi-asserted-by":"crossref","unstructured":"Jones BP , Williams NJ , Saso S , et al ; Uterine transplantation in transgender women. BJOG: An International Journal of Obstetrics & Gynaecology, 2018.","DOI":"10.1111\/1471-0528.15438"},{"key":"2020050722471641000_45.10.687.13","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jogoh.2018.01.003","article-title":"Which neovagina reconstruction procedure for women with Mayer-Rokitansky-K\u00fcster-Hauser syndrome in the uterus transplantation era? 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