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Changes in ipsilateral anterior circulation territory temperature (IACT) were estimated in eight patients as a result of 10\u2005min of a cold saline infusion of 33\u2005ml\/min. During ICSI, the measured JVBT dropped by 0.76\u00b10.18\u00b0C while the modeled JVBT decreased by 0.86\u00b10.18\u00b0C. The modeled IACT decreased by 2.1\u00b10.23\u00b0C. In the inverse model, IACT decreased by 1.9\u00b10.23\u00b0C. The results of this study suggest that mild cerebral hypothermia can be induced rapidly and safely with ICSI in the neuroangiographical setting. The JVBT corrected mathematical model can be used as a non-invasive estimate of transient and steady state cerebral temperature changes.<\/jats:p>","DOI":"10.1136\/neurintsurg-2011-010150","type":"journal-article","created":{"date-parts":[[2012,1,24]],"date-time":"2012-01-24T00:24:12Z","timestamp":1327364652000},"page":"165-171","source":"Crossref","is-referenced-by-count":25,"title":["Brain temperature changes during selective cooling with endovascular intracarotid cold saline infusion: simulation using human data fitted with an integrated mathematical model"],"prefix":"10.1136","volume":"5","author":[{"given":"Matthew Aaron Harold","family":"Neimark","sequence":"first","affiliation":[{"name":"Department of Radiology, SUNY Downstate, Brooklyn, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelos Aristeidis","family":"Konstas","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, 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