{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T18:27:38Z","timestamp":1780511258164,"version":"3.54.1"},"reference-count":15,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2012,10,30]]},"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Posterior circulation perforator artery aneurysms are sparsely reported in the literature. The natural history of these rare lesions remains unclear and their diagnosis and management are not well-defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed our institution's medical records and performed a comprehensive literature search for cases of posterior circulation perforator aneurysms. Diagnostic imaging, management and clinical outcomes were the primary components of interest.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our first case was a 58-year-old patient who developed an infarct after attempted endovascular treatment of a basilar perforator artery aneurysm, the second case was a 55-year-old patient with a posterior cerebral artery perforator aneurysm who did well with conservative management and the third case was a 68-year-old patient who suffered an infarct after successful Onyx embolization of a superior cerebellar artery perforator aneurysm. From the literature we identified four case reports and four case series, all describing aneurysmal lesions of the basilar perforator arteries, giving a total of 17 cases including those from our institution. All cases presented with subarachnoid hemorrhage although 47% of initial vascular imaging studies failed to reveal the aneurysm. Cumulatively, 41% of patients were treated with microsurgery, 35% were treated with endovascular therapy and 24% were managed conservatively with subsequent spontaneous aneurysm resolution at a mean interval of 10\u2005months after rupture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Perforator aneurysms of the posterior circulation are diagnostic and therapeutic challenges. Both microsurgical and endovascular treatment of posterior circulation perforator aneurysms are technically difficult, necessitating comprehensive management by an experienced cerebrovascular team.<\/jats:p><\/jats:sec>","DOI":"10.1136\/neurintsurg-2012-010557","type":"journal-article","created":{"date-parts":[[2012,11,24]],"date-time":"2012-11-24T02:07:14Z","timestamp":1353722834000},"page":"546-551","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":44,"title":["Perforator aneurysms of the posterior circulation: case series and review of the literature"],"prefix":"10.1136","volume":"5","author":[{"given":"Dale","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M","family":"Starke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avery J","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal F","family":"Kassell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth C","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2012,11,23]]},"reference":[{"key":"2024052300202845000_5.6.546.1","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1097\/00006123-200210001-00004","article-title":"Aneurysms","volume":"51","author":"Rhoton","year":"2002","journal-title":"Neurosurgery"},{"key":"2024052300202845000_5.6.546.2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.73.1.0018"},{"key":"2024052300202845000_5.6.546.3","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.73.1.0037"},{"key":"2024052300202845000_5.6.546.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11314-6"},{"key":"2024052300202845000_5.6.546.5","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.569269"},{"key":"2024052300202845000_5.6.546.6","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00006123-199608000-00034","article-title":"Distal basilar perforator artery aneurysm: case report","volume":"39","author":"Ghogawala","year":"1996","journal-title":"Neurosurgery"},{"key":"2024052300202845000_5.6.546.7","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1007\/s00701-005-0615-2","article-title":"Surgical treatment of a basilar perforator aneurysm not accessible to endovascular treatment","volume":"147","author":"Hamel","year":"2005","journal-title":"Acta Neurochir (Wien)"},{"key":"2024052300202845000_5.6.546.8","doi-asserted-by":"publisher","DOI":"10.3171\/JNS-07\/09\/0654"},{"key":"2024052300202845000_5.6.546.9","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1007\/s00701-009-0416-0","article-title":"Pre-mesencephalic subarachnoid hemorrhage: rupture of tiny aneurysms of the basilar artery perforator","volume":"151","author":"Park","year":"2009","journal-title":"Acta Neurochir (Wien)"},{"key":"2024052300202845000_5.6.546.10","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3109\/02688690903572095","article-title":"An unusual case of spontaneous subarachnoid haemorrhage\u2014a ruptured aneurysm of a basilar perforator artery","volume":"24","author":"Mathieson","year":"2010","journal-title":"Br J Neurosurg"},{"key":"2024052300202845000_5.6.546.11","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jocn.2011.04.049","article-title":"An endovascular approach to ruptured aneurysms of the circumferential branch of the basilar artery","volume":"19","author":"Chen","year":"2012","journal-title":"J Clin Neurosci"},{"key":"2024052300202845000_5.6.546.12","doi-asserted-by":"crossref","unstructured":"Nyberg EM Chaudry MI Turk AS . Report of two cases of a rare cause of subarachnoid hemorrhage including unusual presentation and an emerging and effective treatment option. J Neurointerv Surg Published Online First: 28 July 2012. doi:10.1136\/neurintsurg-2012-010387","DOI":"10.1136\/neurintsurg-2012-010387"},{"key":"2024052300202845000_5.6.546.13","doi-asserted-by":"crossref","unstructured":"Gross BA Puri AS Du R . Basilar trunk perforator artery aneurysms. Case report and literature review. Neurosurg Rev Published Online First: 2 Sept 2012. doi: 10.1007\/s10143-012-0422-1","DOI":"10.1007\/s10143-012-0422-1"},{"key":"2024052300202845000_5.6.546.14","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-198912000-00009"},{"key":"2024052300202845000_5.6.546.15","first-page":"80","article-title":"The surgical anatomy of the perforating branches of the basilar artery","volume":"33","author":"Marinkovic","year":"1993","journal-title":"Neurosurgery"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/neurintsurg-2012-010557","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T08:55:35Z","timestamp":1716454535000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/neurintsurg-2012-010557"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,23]]},"references-count":15,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2013,9,27]]},"published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1136\/neurintsurg-2012-010557"],"URL":"https:\/\/doi.org\/10.1136\/neurintsurg-2012-010557","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,23]]}}}