{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T03:16:34Z","timestamp":1782270994112,"version":"3.54.5"},"reference-count":18,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2013,5,14]]},"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec><jats:title>Introduction and purpose<\/jats:title><jats:p>Symptomatic acute basilar thrombosis is associated with a high mortality rate. Aggressive endovascular management has led to survival rates of 35\u201350%. We report the largest series of endovascular reconstruction of occluded dominant vertebral arteries prior to basilar thrombectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A prospective database since August 2010 of all neuroendovascular interventions was mined for patients undergoing basilar artery thrombolysis from which a group with vertebral artery reconstruction was selected. Patient charts were retrospectively reviewed for relevant clinical, technical, and outcome data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From August 2010 to September 2012, six patients were identified who underwent vertebral reconstruction prior to basilar thrombectomy. Patients ranged in age from 42 to 57 years (mean 51 years). Mean time from symptoms until recanalization was approximately 6\u2005h. Angiographic Thrombolysis in Cerebral Infarction IIB reconstitution of the basilar trunk was achieved in all cases. There were no technical complications. Two patients had care withdrawn secondary to massive completed brainstem infarction and poor neurological status post intervention. Three patients are now independent at 12, 14, and 31\u2005months, respectively. One patient, after\u00a0a follow-up of only 8\u2005months, has achieved a modified Rankin Scale score of 3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Complete vertebral occlusion below a basilar thrombus can be recanalized prior to thrombectomy. In this case series, 100% of the acutely occluded vertebral arteries could be opened using either anterograde or retrograde access. However, basilar thrombosis continues to be a devastating illness, with one-third of the patients in this series dying of progressive infarction despite angiographic patency of the large conduit vessels with technical complications.<\/jats:p><\/jats:sec>","DOI":"10.1136\/neurintsurg-2013-010719","type":"journal-article","created":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T03:41:46Z","timestamp":1370403706000},"page":"379-383","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Endovascular reconstruction of vertebral artery occlusion prior to basilar thrombectomy in a series of six patients presenting with acute symptomatic basilar thrombosis"],"prefix":"10.1136","volume":"6","author":[{"given":"Robert D","family":"Ecker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystiana A","family":"Tsujiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher B","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Cushing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,6,4]]},"reference":[{"key":"2024052300302911000_6.5.379.1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.4065\/72.11.1005","article-title":"Intra-arterial thrombolysis in acute basilar artery thromboembolism: the initial Mayo Clinic experience","volume":"72","author":"Wijdicks","year":"1997","journal-title":"Mayo Clin Proc Mayo Clin"},{"key":"2024052300302911000_6.5.379.2","first-page":"1221","article-title":"Relationship between clot location and outcome after basilar artery thrombolysis","volume":"18","author":"Cross","year":"1997","journal-title":"AJNR Am J Neur"},{"key":"2024052300302911000_6.5.379.3","first-page":"1557","article-title":"Collateral circulation and outcome after basilar artery thrombolysis","volume":"19","author":"Cross","year":"1998","journal-title":"AJNR Am J Neur"},{"key":"2024052300302911000_6.5.379.4","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1136\/neurintsurg-2011-010139","article-title":"Stenting of complete vertebral artery ostial occlusion in a patient with medically refractory vertebrobasilar ischemia","volume":"4","author":"Noorian","year":"2012","journal-title":"J Neurointervent Surg"},{"key":"2024052300302911000_6.5.379.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2007.07.073"},{"key":"2024052300302911000_6.5.379.6","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e31822e074c"},{"key":"2024052300302911000_6.5.379.7","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1007\/s00701-012-1398-x","article-title":"Acute to subacute surgical revascularization for progressing stroke in atherosclerotic vertebrobasilar occlusion","volume":"154","author":"Inoue","year":"2012","journal-title":"Acta Neurochir"},{"key":"2024052300302911000_6.5.379.8","first-page":"e277","article-title":"Acute vertebrobasilar artery thrombosis: long-term benefit of vertebral artery stenting","volume":"48","author":"Hassan","year":"2007","journal-title":"Singapore Med J"},{"key":"2024052300302911000_6.5.379.9","doi-asserted-by":"publisher","DOI":"10.1136\/jnis.2009.002139"},{"key":"2024052300302911000_6.5.379.10","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1136\/jnis.2010.004150","article-title":"Vertebral artery stenting in a patient with reversed flow in the anterior spinal artery","volume":"4","author":"Dubow","year":"2012","journal-title":"J Neurointervent Surg"},{"key":"2024052300302911000_6.5.379.11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041544"},{"key":"2024052300302911000_6.5.379.12","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.666867"},{"key":"2024052300302911000_6.5.379.13","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31824e8f40"},{"key":"2024052300302911000_6.5.379.14","doi-asserted-by":"crossref","first-page":"773","DOI":"10.3174\/ajnr.A0906","article-title":"Transluminal angioplasty and stenting for intracranial vertebrobasilar occlusive lesions in acute stroke patients","volume":"29","author":"Imai","year":"2008","journal-title":"AJNR Am J Neur"},{"key":"2024052300302911000_6.5.379.15","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1136\/jnis.2011.004689","article-title":"Angioplasty and stent placement for complete occlusion of the vertebral artery secondary to giant cell arteritis","volume":"4","author":"Dementovych","year":"2012","journal-title":"J Neurointervent Surg"},{"key":"2024052300302911000_6.5.379.16","doi-asserted-by":"crossref","first-page":"E251","DOI":"10.1227\/NEU.0b013e3182186811","article-title":"Delayed endovascular revascularization in a patient with progressive neurological deterioration from bilateral intracranial vertebral artery occlusions: case report","volume":"69","author":"Ogilvy","year":"2011","journal-title":"Neurosurgery"},{"key":"2024052300302911000_6.5.379.17","doi-asserted-by":"crossref","unstructured":"Kole M, Amin B, Marin H, et al. Intracranial angioplasty and stent placement for direct cerebral revascularization of nonacute intracranial occlusions and near occlusions. Neurosurg Focus 2009;26:E3. doi:10.3171\/2008.12.FOCUS08269.","DOI":"10.3171\/2008.12.FOCUS08269"},{"key":"2024052300302911000_6.5.379.18","first-page":"9","article-title":"Clinical outcome of patients with acute posterior circulation stroke and bilateral vertebral artery occlusion","volume":"4","author":"Tariq","year":"2011","journal-title":"J Vasc Interv Neurol"}],"updated-by":[{"DOI":"10.1136\/neurintsurg-2013-010719corr1","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2014,6,28]],"date-time":"2014-06-28T00:00:00Z","timestamp":1403913600000}}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/neurintsurg-2013-010719","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T09:14:20Z","timestamp":1716455660000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/neurintsurg-2013-010719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,4]]},"references-count":18,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,5,9]]},"published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1136\/neurintsurg-2013-010719"],"URL":"https:\/\/doi.org\/10.1136\/neurintsurg-2013-010719","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,4]]}}}