{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:20:43Z","timestamp":1783776043136,"version":"3.55.0"},"reference-count":32,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2014,3,4]]},"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Although intracranial stenting has been associated with in-stent stenosis, the vascular response of cerebral vessels to the deployment of the Enterprise vascular reconstruction device is poorly defined.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To evaluate the change in parent vessel caliber that ensues after Enterprise stent placement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Seventy-seven patients with 88 aneurysms were treated using Enterprise stent-assisted coil embolization and underwent high-resolution three-dimensional rotational angiography followed by three-dimensional edge-detection filtering to remove windowing-dependence measurement artifact. Orthogonal diameters and cross-sectional areas (CSAs) were measured proximal and distal on either side of the leading stent edge (points A, B), trailing stent edge (points D, E), and at mid-stent (point C).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Enterprise stent deployment caused an instant increase in the parent artery CSA by 8.98% at D, which was followed 4\u20136\u2005months later by significant in-stent stenosis (15.78% at A, 27.24% at B, 10.68% at C, 32.12% at D, and 28.28% at E) in the stented artery. This time-dependent phenomenon showed resolution which was complete by 12\u201324\u2005months after treatment. This target vessel stenosis showed significant age dependence with greater response in the young. No flow-limiting stenosis requiring treatment was observed in this series.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Use of the Enterprise stent is associated with a significant dynamic and spontaneously resolvable age-dependent in-stent stenosis. Further study is warranted on the clinical impact, if any, of this occurrence.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2013-011074","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T23:57:26Z","timestamp":1395359846000},"page":"297-302","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":25,"title":["Enterprise stenting for intracranial aneurysm treatment induces dynamic and reversible age-dependent stenosis in cerebral arteries"],"prefix":"10.1136","volume":"7","author":[{"given":"Bulang","family":"Gao","sequence":"first","affiliation":[{"name":"Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina G","family":"Safain","sequence":"additional","affiliation":[{"name":"Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel M","family":"Malek","sequence":"additional","affiliation":[{"name":"Cerebrovascular and Endovascular Division, Department of Neurosurgery, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,3,20]]},"reference":[{"key":"2025092912450104000_7.4.297.1","first-page":"584","article-title":"Treatment of intracranial broad-neck aneurysms with a new self-expanding stent and coil embolization","volume":"25","author":"Alfke","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025092912450104000_7.4.297.2","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000290890.62201.A9"},{"key":"2025092912450104000_7.4.297.3","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000159645.86823.AF"},{"key":"2025092912450104000_7.4.297.4","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000219853.56553.71"},{"key":"2025092912450104000_7.4.297.5","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1227\/01.NEU.0000186026.12709.BC","article-title":"Three-dimensional rotational angiographic detection of in-stent stenosis in wide-necked aneurysms treated with a self-expanding intracranial stent","volume":"57","author":"Hoit","year":"2005","journal-title":"Neurosurgery"},{"key":"2025092912450104000_7.4.297.6","first-page":"1751","article-title":"Initial clinical experience with a new self-expanding nitinol stent for the treatment of intracranial cerebral aneurysms: the Cordis Enterprise stent","volume":"26","author":"Higashida","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025092912450104000_7.4.297.7","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-007-0232-2"},{"key":"2025092912450104000_7.4.297.8","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e31828046a6"},{"key":"2025092912450104000_7.4.297.9","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e318228490c"},{"key":"2025092912450104000_7.4.297.10","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182571953"},{"key":"2025092912450104000_7.4.297.11","doi-asserted-by":"publisher","DOI":"10.1177\/152660280200900423"},{"key":"2025092912450104000_7.4.297.12","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1007\/s10554-011-0007-z","article-title":"Assessment of the relation between IVUS measurements and clinical outcome in elderly patients after sirolimus-eluting stent implantation for de novo coronary lesions","volume":"28","author":"Du","year":"2012","journal-title":"Int J Cardiovasc Imaging"},{"key":"2025092912450104000_7.4.297.13","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0869"},{"key":"2025092912450104000_7.4.297.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.1.44"},{"key":"2025092912450104000_7.4.297.15","doi-asserted-by":"publisher","DOI":"10.1136\/heart.88.4.401"},{"key":"2025092912450104000_7.4.297.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00053-3"},{"key":"2025092912450104000_7.4.297.17","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01329.2003"},{"key":"2025092912450104000_7.4.297.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(03)00068-X"},{"key":"2025092912450104000_7.4.297.19","doi-asserted-by":"publisher","DOI":"10.1114\/1.276"},{"key":"2025092912450104000_7.4.297.20","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s00270-004-0040-6","article-title":"Flow velocities after carotid artery stenting: impact of stent design. 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