{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:41:10Z","timestamp":1792698070623,"version":"4.5.0"},"reference-count":21,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2015,7,20]]},"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>The natural history of acute ischemic stroke (AIS) due to basilar artery occlusion (BAO) is poor. Endovascular reperfusion therapy (EVT) improves recanalization rates in patients with emergent large vessel intracranial occlusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To examine the hypothesis that good collateral patterns identified by pretreatment CT angiography (CTA) might be associated with favorable outcomes after EVT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a retrospective chart review of patients presenting with AIS due to BAO in a tertiary care stroke center during a 4-year period. BAO was diagnosed by CTA in all cases. Admission stroke severity was documented using the National Institute of Health Stroke Scale (NIHSS) score. Pretreatment collateral score for posterior circulation was defined as follows: 0, no posterior communicating artery (PCOM); 1, unilateral PCOM; 2, bilateral PCOM. Favorable outcome was defined as modified Rankin Scale score of 0\u20132 at 3\u2005months.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 21 patients with AIS due to BAO (age range 31\u201384\u2005years, median admission NIHSS score: 18 points, range 2\u201338) underwent EVT. Eleven of 21 patients (52.4%) had bilateral PCOMs, while unilateral PCOM was seen in 3 patients (14.3%). Patients with bilateral PCOMs tended (p=0.261) to have less severe stroke at admission than those with absent\/unilateral PCOM (median NIHSS score 18 vs 27 points). Neurological improvement during hospitalization (quantified by the median decrease in NIHSS score) and the rate of 3-month functional independence were greater in patients with good collaterals (16 vs 0 points (p=0.016) and 72.7% vs 0% (p=0.001)).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The presence of bilateral PCOMs on pretreatment CTA appears to be associated with more favorable outcomes in BAO treated with EVT.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2015-011883","type":"journal-article","created":{"date-parts":[[2015,8,17]],"date-time":"2015-08-17T22:20:12Z","timestamp":1439850012000},"page":"783-786","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":71,"title":["Posterior circulation CT angiography collaterals predict outcome of endovascular acute ischemic stroke therapy for basilar artery occlusion"],"prefix":"10.1136","volume":"8","author":[{"given":"Nitin","family":"Goyal","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Tsivgoulis","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA"},{"name":"Second Department of Neurology, \u201cAttikon\u201d Hospital, School of Medicine, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Nickele","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinodh T","family":"Doss","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA"},{"name":"Department of Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Hoit","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei V","family":"Alexandrov","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Arthur","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Elijovich","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee, USA"},{"name":"Department of Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,8,17]]},"reference":[{"key":"2025092911563573000_8.8.783.1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000247897.33267.42"},{"key":"2025092911563573000_8.8.783.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414905"},{"key":"2025092911563573000_8.8.783.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411587"},{"key":"2025092911563573000_8.8.783.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1415061"},{"key":"2025092911563573000_8.8.783.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414792"},{"key":"2025092911563573000_8.8.783.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503780"},{"key":"2025092911563573000_8.8.783.7","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2014-011418"},{"key":"2025092911563573000_8.8.783.8","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000202582.29510.6b"},{"key":"2025092911563573000_8.8.783.9","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70229-0"},{"key":"2025092911563573000_8.8.783.10","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70173-5"},{"key":"2025092911563573000_8.8.783.11","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24336"},{"key":"2025092911563573000_8.8.783.12","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3817"},{"key":"2025092911563573000_8.8.783.13","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2985"},{"key":"2025092911563573000_8.8.783.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.8.3.383"},{"key":"2025092911563573000_8.8.783.15","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000082721.62796.09"},{"key":"2025092911563573000_8.8.783.16","doi-asserted-by":"crossref","unstructured":"Elijovich L , Goyal N , Mainali S , et al . CTA collateral score predicts infarct volume and clinical outcome after endovascular therapy for acute ischemic stroke: a retrospective chart review. J Neurointerv Surg Published Online First: 28 Apr 2015. doi:10.1136\/neurintsurg-2015-011731 doi:10.1136\/neurintsurg-2015-011731","DOI":"10.1136\/neurintsurg-2015-011731"},{"key":"2025092911563573000_8.8.783.17","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000106760.25228.2C"},{"key":"2025092911563573000_8.8.783.18","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.499392"},{"key":"2025092911563573000_8.8.783.19","first-page":"1557","article-title":"Collateral circulation and outcome after basilar artery thrombolysis","volume":"19","author":"Cross","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025092911563573000_8.8.783.20","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2214\/ajr.119.3.597","article-title":"Angiographic implications in diagnosis and prognosis of basilar artery occlusion","volume":"119","author":"Moscow","year":"1973","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"2025092911563573000_8.8.783.21","first-page":"9","article-title":"Patterns of collateral formation in basilar artery steno-occlusive diseases","volume":"6","author":"Alqadri","year":"2013","journal-title":"J Vasc Interv Neurol"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/neurintsurg-2015-011883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T18:56:44Z","timestamp":1759172204000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/neurintsurg-2015-011883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,17]]},"references-count":21,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,7,14]]},"published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1136\/neurintsurg-2015-011883"],"URL":"https:\/\/doi.org\/10.1136\/neurintsurg-2015-011883","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,17]]}}}