{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:13:31Z","timestamp":1789002811599,"version":"build-2803163510"},"reference-count":30,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2015,9,17]]},"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Posterior fossa arteriovenous malformations (AVMs) are considered to have a higher risk of poor outcome, as are AVMs with associated aneurysms. We postulated that posterior fossa malformations may be more prone to associated feeder vessel aneurysms, and to aneurysmal source of hemorrhage.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To examine the prevalence and hemorrhagic risk of posterior fossa AVM-associated feeder vessel aneurysms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective review of AVMs was performed with attention paid to location and presence of aneurysms. The hemorrhage status and origin of the hemorrhage was also reviewed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>571 AVMs were analyzed. Of 90 posterior fossa AVMs, 34 (37.8%) had aneurysms (85% feeder vessel, 9% intranidal, 15% with both). Of the 481 supratentorial AVMs, 126 (26.2%) harbored aneurysms (65% feeder vessel, 29% intranidal, 6% both). The overall incidence of feeder aneurysms was higher in posterior fossa AVMs, which were evident in 34.4% of infratentorial AVMs compared to 18.5% of supratentorial malformations (p&lt;0.01). The presence of intranidal aneurysms was similar in both groups (9.2% vs 8.8%). Feeder artery aneurysms were much more likely to be the source of hemorrhage in posterior fossa AVMs than in supratentorial AVMs (30% vs 7.6%, p&lt;0.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Posterior fossa AVMs are more prone to developing associated aneurysms, specifically feeder vessel aneurysms. Feeder vessel aneurysms are more likely to be the source of hemorrhage in the posterior fossa. As such, they may be the most appropriate targets for initial and prompt control by embolization or surgery due to their elevated threat.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2015-012005","type":"journal-article","created":{"date-parts":[[2015,10,7]],"date-time":"2015-10-07T22:28:58Z","timestamp":1444256938000},"page":"1021-1024","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":32,"title":["Increased prevalence and rupture status of feeder vessel aneurysms in posterior fossa arteriovenous malformations"],"prefix":"10.1136","volume":"8","author":[{"given":"Jennifer","family":"Orning","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sepideh","family":"Amin-Hanjani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Hamade","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinjian","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad A","family":"Hage","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Aletich","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fady","family":"Charbel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alaraj","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,10,7]]},"reference":[{"key":"2025092911360491000_8.10.1021.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07946-1"},{"key":"2025092911360491000_8.10.1021.2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s11883-012-0257-9","article-title":"Management of ruptured brain arteriovenous malformations","volume":"14","author":"Zacharia","year":"2012","journal-title":"Curr Atheroscler Rep"},{"key":"2025092911360491000_8.10.1021.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(98)00037-8"},{"key":"2025092911360491000_8.10.1021.4","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.73.3.294"},{"key":"2025092911360491000_8.10.1021.5","doi-asserted-by":"publisher","DOI":"10.1007\/BF01400524"},{"key":"2025092911360491000_8.10.1021.6","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.89.4.0539"},{"key":"2025092911360491000_8.10.1021.7","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1017\/S0317167100027487","article-title":"Cerebral arteriovenous malformations with associated arterial aneurysms: hemodynamic and therapeutic considerations.","volume":"15","author":"Kondziolka","year":"1988","journal-title":"Can J Neurol Sci"},{"key":"2025092911360491000_8.10.1021.8","first-page":"793","article-title":"Cerebral arteriovenous malformations and associated aneurysms: analysis of 305 cases from a series of 662 patients","volume":"46","author":"Meisel","year":"2000","journal-title":"Neurosurgery"},{"key":"2025092911360491000_8.10.1021.9","doi-asserted-by":"crossref","unstructured":"Lv X , Li Y . 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