{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T19:19:09Z","timestamp":1778786349232,"version":"3.51.4"},"reference-count":19,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2016,3,12]]},"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Embolization of thrombus fragments in a new vascular territory is a potential adverse event in neurothrombectomy. This study was performed to evaluate the safety and feasibility of a novel approach combining proximal balloon occlusion and distal aspiration to prevent distal thrombembolic complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with ischemic stroke meeting the following inclusion criteria were eligible: occlusion in the anterior circulation, neurothrombectomy using a balloon catheter for proximal flow arrest, and an intermediate catheter for distal aspiration. Pre- and post-interventional Thrombolysis In Cerebral Infarction (TICI) scores were assessed. Clinical presentation at admission and discharge and after 3\u2005months was also evaluated and complications (particularly new thrombembolic events) were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We retrospectively identified 31 patients from our prospectively collected stroke database who met the inclusion criteria. In all patients the initial TICI was 0. A TICI score of \u22652b was achieved in 96.8%. No new thrombembolic complications occurred. The median NIH Stroke Scale score was 19 at admission and 4.5 at discharge. After 3\u2005months, 51.6% of the patients had a favorable clinical outcome (modified Rankin Scale score 0\u20132) and 19.3% had died.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A combination of proximal internal carotid artery occlusion using a balloon catheter and distal aspiration through an intermediate catheter represents a safe and efficient adjunct to mechanical thrombectomy with stent retrievers. In our patient cohort, no new thrombembolic complications were detected.<\/jats:p><\/jats:sec>","DOI":"10.1136\/neurintsurg-2015-012208","type":"journal-article","created":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T17:35:45Z","timestamp":1460136945000},"page":"346-351","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":59,"title":["Combined proximal balloon occlusion and distal aspiration: a new approach to prevent distal embolization during neurothrombectomy"],"prefix":"10.1136","volume":"9","author":[{"given":"Sibylle","family":"Stampfl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0672-5718","authenticated-orcid":false,"given":"Johannes","family":"Pfaff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Herweh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirko","family":"Pham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Schieber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A","family":"Ringleb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Bendszus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus A","family":"M\u00f6hlenbruch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,4,7]]},"reference":[{"key":"2024052303035207000_9.4.346.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411587"},{"key":"2024052303035207000_9.4.346.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1415061"},{"key":"2024052303035207000_9.4.346.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414905"},{"key":"2024052303035207000_9.4.346.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503780"},{"key":"2024052303035207000_9.4.346.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414792"},{"key":"2024052303035207000_9.4.346.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61299-9"},{"key":"2024052303035207000_9.4.346.7","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3462"},{"key":"2024052303035207000_9.4.346.8","doi-asserted-by":"crossref","unstructured":"Stampfl S , Kabbasch C , M\u00fcller M , et al . Initial experience with a new distal intermediate and aspiration catheter in the treatment of acute ischemic stroke: clinical safety and efficacy. J Neurointerv Surg. 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Comparison of clinical outcomes in patients with acute ischemic strokes treated with mechanical thrombectomy using either Solumbra or ADAPT techniques. J Neurointerv Surg. 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