{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T20:31:39Z","timestamp":1784665899931,"version":"3.55.0"},"reference-count":32,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2017,1,9]]},"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Flow diversion represents a novel but definitive treatment for recurrent and difficult-to-coil aneurysms of the anterior communicating artery (ACoA) region, of which reports are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the effectiveness of the Pipeline embolization device (PED) in treating aneurysms in the ACoA region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed an IRB-approved database of patients with an aneurysm at a single institution for patients with ACoA or A1\u2013A2 aneurysms treated with PED. Data analyzed included demographics, aneurysm characteristics, procedural details, follow-up results, and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 50 procedures were performed on 41 patients, including seven patients who underwent bilateral \u2018H-pipe\u2019 PED placement. The average age was 56\u2005years and 46% of the patients were female. The average aneurysm size was 4.5\u2005mm, and two large (&gt;10\u2005mm) aneurysms were treated. The vessel of origin was either the ACoA (26 aneurysms, 63%) or the A1\u2013A2 junction (15 aneurysms, 37%). Eighteen patients (44%) had prior subarachnoid hemorrhage and 20 had previously been treated either with clipping (6 aneurysms, 15%) or coiling (14 aneurysms, 34%). Procedural success was achieved in 48\/50 cases (96%) and two cases were aborted. Coils were deployed adjunctively in two cases (4%). Procedural outcomes included no deaths, one major ischemic stroke (2%), and two patients with intracranial hemorrhage (4%). Complete aneurysm occlusion was achieved in 81% of patients at 6\u2005months and 85% of patients at last follow-up digital subtraction angiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The PED can be used safely and effectively in the treatment of aneurysms of the ACoA region. This represents a good alternative treatment option to microsurgical clipping and endovascular coiling.<\/jats:p><\/jats:sec>","DOI":"10.1136\/neurintsurg-2016-012946","type":"journal-article","created":{"date-parts":[[2017,1,28]],"date-time":"2017-01-28T02:50:27Z","timestamp":1485571827000},"page":"679-685","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":59,"title":["Endovascular flow diversion for treatment of anterior communicating artery region cerebral aneurysms: a single-center cohort of 50 cases"],"prefix":"10.1136","volume":"9","author":[{"given":"Geoffrey P","family":"Colby","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew T","family":"Bender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Mei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narlin","family":"Beaty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael J","family":"Tamargo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander L","family":"Coon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,1,27]]},"reference":[{"key":"2024052303440516000_9.7.679.1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.73.1.0018"},{"key":"2024052303440516000_9.7.679.2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001667"},{"key":"2024052303440516000_9.7.679.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2006.06.025"},{"key":"2024052303440516000_9.7.679.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2008.01.056"},{"key":"2024052303440516000_9.7.679.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11314-6"},{"key":"2024052303440516000_9.7.679.6","doi-asserted-by":"publisher","DOI":"10.3171\/2011.1.JNS101528"},{"key":"2024052303440516000_9.7.679.7","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-015-1630-5"},{"key":"2024052303440516000_9.7.679.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67214-5"},{"key":"2024052303440516000_9.7.679.9","doi-asserted-by":"publisher","DOI":"10.4103\/2152-7806.117711"},{"key":"2024052303440516000_9.7.679.10","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2012-010299"},{"key":"2024052303440516000_9.7.679.11","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2015-011894"},{"key":"2024052303440516000_9.7.679.12","doi-asserted-by":"publisher","DOI":"10.1177\/159101991001600204"},{"key":"2024052303440516000_9.7.679.13","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2014-011298"},{"key":"2024052303440516000_9.7.679.14","doi-asserted-by":"crossref","unstructured":"Bender MT , Lin LM , Colby GP , et al . 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