{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:42:23Z","timestamp":1790055743329,"version":"4.0.1"},"reference-count":16,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2018,1,5]]},"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n                  <jats:title>Background and purpose<\/jats:title>\n                  <jats:p>The Barrel vascular reconstruction device (Barrel VRD) is a novel stent with design features that allow endovascular coiling of wide-necked bifurcation aneurysms while preserving adjacent branches, without necessitating dual stent implantation. This study aimed to assess the safety and effectiveness of the Barrel VRD at 12-month follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and methods<\/jats:title>\n                  <jats:p>The Barrel VRD trial is a prospective, multicenter, observational post-marketing registry evaluating the use of the Barrel VRD for treatment of wide-necked bifurcation aneurysms. The primary effectiveness endpoint was successful aneurysm treatment measured by digital subtraction angiography with a Raymond\u2013Roy occlusion grade of 1 or 2 in the absence of retreatment, parent artery stenosis (&gt;50%), or target aneurysm rupture at 12\u2009months. The primary safety endpoint was the absence of neurological death or major stroke at 12 months.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Twenty patients were enrolled from December 2013 to December 2014. The device was implanted in 19 patients with 19 aneurysms (8 middle cerebral artery, 4 anterior communicating artery, 1 internal carotid artery terminus, 4 basilar artery aneurysms; mean dome height 5.7\u00b11.91\u2009mm; mean neck length 4.8\u00b11.35\u2009mm, mean dome-to-neck ratio 1.6\u00b12.0). Coiling was performed in all cases. The primary effectiveness endpoint was achieved in 78.9% of subjects (15\/19; 12 complete occlusions, 3 neck remnants), and the primary safety endpoint was 5.3% (1\/19).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This prospective study demonstrates that the Barrel VRD device resulted in ~80%\u2009occlusion rates and ~5% rates of neurological complications at 1\u2009year after endovascular treatment of wide-necked bifurcation intracranial aneurysms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Registered clinical trial<\/jats:title>\n                  <jats:p>\n                     <jats:bold>NCT02125097;Results.<\/jats:bold>\n                  <\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2017-013602","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T04:47:02Z","timestamp":1518065222000},"page":"969-974","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["The Barrel vascular reconstruction device for endovascular coiling of wide-necked intracranial aneurysms: a multicenter, prospective, post-marketing study"],"prefix":"10.1136","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8424-4464","authenticated-orcid":false,"given":"Benjamin","family":"Gory","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, University Hospital of Nancy, Nancy, France"},{"name":"INSERM U947, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3975-3865","authenticated-orcid":false,"given":"Rapha\u00ebl","family":"Blanc","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Rothschild Foundation, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Turjman","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, H\u00f4pital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Berge","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Bordeaux University Hospital, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1354-4328","authenticated-orcid":false,"given":"Michel","family":"Piotin","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Rothschild Foundation, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,2,2]]},"reference":[{"key":"2025092910494942000_10.10.969.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-014-2047-3"},{"key":"2025092910494942000_10.10.969.2","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0140-6736(14)60975-2","article-title":"The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT)","volume":"385","author":"Molyneux","year":"2015","journal-title":"The Lancet"},{"key":"2025092910494942000_10.10.969.3","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1177\/1591019917717576","article-title":"One-year efficacy and safety of the Trufill DCS Orbit and Orbit Galaxy detachable coils in the endovascular treatment of intracranial aneurysms: results from the TRULINE study","volume":"23","author":"Gory","year":"2017","journal-title":"Interv Neuroradiol"},{"key":"2025092910494942000_10.10.969.4","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4060"},{"key":"2025092910494942000_10.10.969.5","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3781"},{"key":"2025092910494942000_10.10.969.6","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4578"},{"key":"2025092910494942000_10.10.969.7","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4392"},{"key":"2025092910494942000_10.10.969.8","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1093\/neuros\/nyw131","article-title":"One-year angiographic results after pCONus 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aneurysms","volume":"80","author":"Gory","year":"2017","journal-title":"Neurosurgery"},{"key":"2025092910494942000_10.10.969.9","doi-asserted-by":"publisher","DOI":"10.1161\/hs0901.095600"},{"key":"2025092910494942000_10.10.969.10","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000001106"},{"key":"2025092910494942000_10.10.969.11","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4506"},{"key":"2025092910494942000_10.10.969.12","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000415"},{"key":"2025092910494942000_10.10.969.13","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.558114"},{"key":"2025092910494942000_10.10.969.14","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4457"},{"key":"2025092910494942000_10.10.969.15","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000669"},{"key":"2025092910494942000_10.10.969.16","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.wneu.2016.12.065","article-title":"PulseRider for 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