{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:13:43Z","timestamp":1790266423358,"version":"4.1.0"},"reference-count":34,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2019,2,19]]},"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background and objective<\/jats:title>\n                    <jats:p>Pulsatile tinnitus (PT) can be debilitating and lead to significant morbidity. Cerebral venous sinus lesions, such as venous sinus stenosis, diverticula, and high-riding jugular bulb, are uncommon causes of PT, for which there is no standard treatment. Endovascular interventions have shown promising results for PT secondary to idiopathic intracranial hypertension, and may be a valid therapeutic option for isolated venous PT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic literature review on the outcome and safety of endovascular treatment for patients with isolated, debilitating venous PT. The venous lesion characteristics, endovascular techniques, complications, and clinical outcomes were assessed. In addition, an illustrative case of endovascular stenting for PT caused by venous sinus stenosis was included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 41 patients (90.2% female) from 26 papers were included. The median age was 46 years (IQR 23; range 25\u201372 years). Focal venous sinus stenosis (20 patients) and sinus diverticula (14 patients) were the most common culprit lesions. Endovascular treatment included venous sinus stenting in 35 patients, 11 of whom had adjuvant coil embolization, and coil embolization alone in six patients. Complete resolution of the tinnitus was achieved in 95.1% of patients. There was one complication of cerebellar infarct, and no procedure-related mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with debilitating PT secondary to venous sinus lesions, endovascular treatment by stenting and\/or coil embolization appears to be safe and effective. Prospective randomized studies with objective outcome assessments are needed to confirm the treatment benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/neurintsurg-2019-014725","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T17:15:33Z","timestamp":1552583733000},"page":"841-846","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":43,"title":["Endovascular treatment of debilitating tinnitus secondary to cerebral venous sinus abnormalities: a literature review and technical illustration"],"prefix":"10.1136","volume":"11","author":[{"given":"I-Hsiao","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor M","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4952-8490","authenticated-orcid":false,"given":"Stephanie","family":"Lenck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7182-5112","authenticated-orcid":false,"given":"Patrick","family":"Nicholson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Orru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse M","family":"Klostranec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Krings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2758-3253","authenticated-orcid":false,"given":"Anderson Chun On","family":"Tsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,3,14]]},"reference":[{"key":"2024052305081616000_11.8.841.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60142-7"},{"key":"2024052305081616000_11.8.841.2","doi-asserted-by":"publisher","DOI":"10.5935\/1808-8694.20130018"},{"key":"2024052305081616000_11.8.841.3","first-page":"251","article-title":"Pulsatile tinnitus: a review","volume":"13","author":"Sharma","year":"2017","journal-title":"B-ENT"},{"key":"2024052305081616000_11.8.841.4","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2013.0451"},{"key":"2024052305081616000_11.8.841.5","doi-asserted-by":"crossref","unstructured":"Nicholson P , Brinjikji W , Radovanovic I , et al . Venous sinus stenting for idiopathic intracranial hypertension: a systematic review and meta-analysis. J Neurointerv Surg 2018.","DOI":"10.1136\/neurintsurg-2018-014172"},{"key":"2024052305081616000_11.8.841.6","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200010)48:4<669::AID-ANA16>3.0.CO;2-6"},{"key":"2024052305081616000_11.8.841.7","first-page":"54","article-title":"A new therapeutic procedure for treatment of objective venous pulsatile tinnitus","volume":"8","author":"Sanchez","year":"2002","journal-title":"Int Tinnitus J"},{"key":"2024052305081616000_11.8.841.8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.100.1.0120"},{"key":"2024052305081616000_11.8.841.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.04.019"},{"key":"2024052305081616000_11.8.841.10","doi-asserted-by":"publisher","DOI":"10.1177\/159101990901500409"},{"key":"2024052305081616000_11.8.841.11","doi-asserted-by":"publisher","DOI":"10.1177\/159101991001600413"},{"key":"2024052305081616000_11.8.841.12","doi-asserted-by":"publisher","DOI":"10.1177\/159101991101700316"},{"key":"2024052305081616000_11.8.841.13","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-011-1202-3"},{"key":"2024052305081616000_11.8.841.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurad.2012.02.001"},{"key":"2024052305081616000_11.8.841.15","doi-asserted-by":"publisher","DOI":"10.1177\/1538574412442593"},{"key":"2024052305081616000_11.8.841.16","first-page":"1010","article-title":"Resolution of pulsatile tinnitus after coil embolization of sigmoid sinus diverticulum","volume":"1","author":"Amans","year":"2014","journal-title":"Austin J Cerebrovasc Dis & Stroke"},{"key":"2024052305081616000_11.8.841.17","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1016\/j.jvir.2014.07.013","article-title":"Endovascular treatment of symptomatic vestibular aqueduct dehiscence as a result of jugular bulb abnormalities","volume":"25","author":"Th\u00e9nint","year":"2014","journal-title":"J Vasc Interv Radiol"},{"key":"2024052305081616000_11.8.841.18","doi-asserted-by":"crossref","unstructured":"Mortimer AM , Harrington T , Steinfort B , et al . Endovascular treatment of jugular bulb diverticula causing debilitating pulsatile tinnitus. BMJ Case Rep 2015;2015.doi:10.1136\/bcr-2014-011609","DOI":"10.1136\/bcr-2014-011609"},{"key":"2024052305081616000_11.8.841.19","doi-asserted-by":"publisher","DOI":"10.1177\/1591019915590367"},{"issue":"1-2","key":"2024052305081616000_11.8.841.20","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1159\/000444507","article-title":"Endovascular management of sigmoid sinus diverticulum","volume":"5","author":"Paramasivam","year":"2016","journal-title":"Interv Neurol"},{"key":"2024052305081616000_11.8.841.21","first-page":"632","article-title":"Stent-assisted coil embolization of a transverse-sigmoid sinus diverticulum presenting with pulsatile tinnitus","volume":"26","author":"Li","year":"2016","journal-title":"Turk Neurosurg"},{"key":"2024052305081616000_11.8.841.22","doi-asserted-by":"crossref","first-page":"e302","DOI":"10.1097\/MAO.0000000000001540","article-title":"Venous diverticula causing pulsatile tinnitus treated with coil embolization and stent placement with resolution of symptoms: report of two cases and review of the literature","volume":"38","author":"Shastri","year":"2017","journal-title":"Otol Neurotol"},{"key":"2024052305081616000_11.8.841.23","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1093\/ons\/opx026","article-title":"Stent placement for disabling pulsatile tinnitus caused by a lateral sinus stenosis: a retrospective study","volume":"13","author":"Lenck","year":"2017","journal-title":"Oper Neurosurg"},{"key":"2024052305081616000_11.8.841.24","doi-asserted-by":"crossref","first-page":"e245","DOI":"10.1212\/WNL.0000000000004032","article-title":"Pearls & oy-sters: retrievable and awake: a case report of solitaire stent employment for venous pulsatile tinnitus","volume":"88","author":"Du","year":"2017","journal-title":"Neurology"},{"key":"2024052305081616000_11.8.841.25","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.wneu.2018.02.087","article-title":"Endovascular treatment of pulsatile tinnitus by sigmoid sinus aneurysm: technical note and review of the literature","volume":"113","author":"Cuellar","year":"2018","journal-title":"World Neurosurg"},{"key":"2024052305081616000_11.8.841.26","doi-asserted-by":"crossref","unstructured":"Lenck S , Vall\u00e9e F , Civelli V , et al . Assessment of blood flow velocities and venous pressures using a dual-sensor guidewire in symptomatic dural sinus stenoses. J Neurosurg 2018:1\u20135.doi:10.3171\/2017.12.JNS172364","DOI":"10.3171\/2017.12.JNS172364"},{"key":"2024052305081616000_11.8.841.27","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.nic.2015.12.007","article-title":"Endovascular interventions for idiopathic intracranial hypertension and venous tinnitus: new horizons","volume":"26","author":"Hui","year":"2016","journal-title":"Neuroimaging Clin N Am"},{"key":"2024052305081616000_11.8.841.28","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.wneu.2017.06.168","article-title":"Computational fluid dynamics simulation of hemodynamic alterations in sigmoid sinus diverticulum and ipsilateral upstream sinus stenosis after stent implantation in patients with pulsatile tinnitus","volume":"106","author":"Han","year":"2017","journal-title":"World Neurosurg"},{"key":"2024052305081616000_11.8.841.29","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1227\/NEU.0000000000000902","article-title":"Sinus wall resurfacing for patients with temporal bone venous sinus diverticulum and ipsilateral pulsatile tinnitus","volume":"77","author":"Song","year":"2015","journal-title":"Neurosurgery"},{"key":"2024052305081616000_11.8.841.30","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822a1c7d"},{"key":"2024052305081616000_11.8.841.31","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012405"},{"key":"2024052305081616000_11.8.841.32","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013155"},{"key":"2024052305081616000_11.8.841.33","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.nic.2015.12.006","article-title":"Venous abnormalities leading to tinnitus: imaging evaluation","volume":"26","author":"Reardon","year":"2016","journal-title":"Neuroimaging Clin N Am"},{"key":"2024052305081616000_11.8.841.34","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182990d52"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/neurintsurg-2019-014725","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T08:31:13Z","timestamp":1716453073000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/neurintsurg-2019-014725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,14]]},"references-count":34,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2019,7,11]]},"published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1136\/neurintsurg-2019-014725"],"URL":"https:\/\/doi.org\/10.1136\/neurintsurg-2019-014725","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,14]]}}}