{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:19:16Z","timestamp":1759191556296,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2019,9,16]]},"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec>\n                  <jats:title>Purpose<\/jats:title>\n                  <jats:p>To determine the effect of general anesthesia (GA) versus conscious sedation (CS) on radiation exposure (RE), procedure time (PT), and fluoroscopy time (FT) in patients receiving endovascular stroke treatment (EST) for large vessel occlusions (LVOs) in the anterior circulation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Retrospective analysis of an institutional review board\u2212approved prospective stroke database of a comprehensive stroke center focusing on RE (as dose area product (DAP) in Gy.cm\u00b2, median (IQR)), PT, and FT (in minutes, median (IQR)) in patients receiving EST for LVOs of the anterior circulation according to the mode of anesthesia during the intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Overall 544 patients were included in this analysis (GA: n=143, CS: n=401). For all included LVOs in the anterior circulation PTs (GA: 69 (44\u2013100); CS: 59 (37\u201399); p=0.235), FTs (GA: 33 (20\u201356); CS: 29 (16\u201351); p=0.286), and RE (DAP, GA: 116.23 (73.47\u2013173.41); CS: 110.5 (68.35\u2013184.65); p=0.929) were comparable. In a subgroup analysis of occlusions of the middle cerebral artery (M1-segment; GA: n=80\/544, 14.7%; CS: n=211\/544, 38.8%), PTs (GA: 69 (37\u2013101); CS: 54 (35 \u2013 89); p=0.223), FTs (GA: 33 (19\u201355); CS: 25 (14\u201348); p=0.264), and RE (DAP, GA: 110.91 (66.8\u2013169.12); CS: 103.8 (63.17\u2013181); p=0.893) were similar.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In this retrospective analysis, no effect of the mode of anesthesia on the radiation exposure during EST was detected as GA and CS showed comparable PT, FT, and DAPs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2019-015357","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T18:18:59Z","timestamp":1569694739000},"page":"455-459","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of mode of anesthesia on radiation exposure in patients undergoing endovascular recanalization of anterior circulation embolic stroke"],"prefix":"10.1136","volume":"12","author":[{"given":"Felix","family":"Hemmerich","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, University of Heidelberg, Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte S","family":"Weyland","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Heidelberg, Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Sch\u00f6nenberger","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A","family":"Ringleb","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus A","family":"M\u00f6hlenbruch","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Heidelberg, Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Bendszus","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Heidelberg, Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0672-5718","authenticated-orcid":false,"given":"Johannes AR","family":"Pfaff","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Heidelberg, Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,9,28]]},"reference":[{"key":"2025092911010700000_12.5.455.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00163-X"},{"key":"2025092911010700000_12.5.455.2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.16623"},{"key":"2025092911010700000_12.5.455.3","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1001\/jamaneurol.2017.4474","article-title":"Effect of general anesthesia and conscious sedation during endovascular therapy on infarct growth and clinical outcomes in acute ischemic stroke: a randomized clinical trial","volume":"75","author":"Simonsen","year":"2018","journal-title":"JAMA Neurol"},{"key":"2025092911010700000_12.5.455.4","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.016554"},{"key":"2025092911010700000_12.5.455.5","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1148\/radiol.2017171002","article-title":"Effect of general anesthesia versus conscious sedation for stroke thrombectomy on angiographic workflow in a randomized trial: a post hoc analysis of the SIESTA Trial","volume":"286","author":"Pfaff","year":"2018","journal-title":"Radiology"},{"key":"2025092911010700000_12.5.455.6","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5920"},{"key":"2025092911010700000_12.5.455.7","unstructured":"Image quality assurance in diagnostic X-ray departments - Part 157: X-ray ordinance acceptance and constancy test of image display systems in their environment. 2014 https:\/\/www.din.de\/en\/getting-involved\/standards-committees\/nar\/standards\/wdc-beuth:din21:216064441."},{"key":"2025092911010700000_12.5.455.8","unstructured":"Image quality assurance in diagnostic X-ray departments - Part 4: Constancy testing of medical X-ray equipment for fluoroscopy. 2007 https:\/\/www.din.de\/en\/getting-involved\/standards-committees\/nar\/standards\/wdc-beuth:din21:99599886."},{"key":"2025092911010700000_12.5.455.9","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5825"},{"key":"2025092911010700000_12.5.455.10","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012812"},{"key":"2025092911010700000_12.5.455.11","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2013-010906"},{"key":"2025092911010700000_12.5.455.12","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1007\/s00330-018-5593-x","article-title":"Dose reference levels and clinical determinants in stroke neuroradiology interventions","volume":"29","author":"Farah","year":"2019","journal-title":"Eur Radiol"},{"key":"2025092911010700000_12.5.455.13","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.1007\/s00330-019-06062-6","article-title":"Proposed achievable levels of dose and impact of dose-reduction systems for thrombectomy in acute ischemic stroke:\u00a0an international, multicentric, retrospective study in 1096 patients","volume":"29","author":"Guenego","year":"2019","journal-title":"Eur Radiol"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/neurintsurg-2019-015357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T18:01:15Z","timestamp":1759168875000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/neurintsurg-2019-015357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,28]]},"references-count":13,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,4,15]]},"published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1136\/neurintsurg-2019-015357"],"URL":"https:\/\/doi.org\/10.1136\/neurintsurg-2019-015357","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"type":"print","value":"1759-8478"},{"type":"electronic","value":"1759-8486"}],"subject":[],"published":{"date-parts":[[2019,9,28]]}}}