{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:16:53Z","timestamp":1791523013062,"version":"4.3.4"},"reference-count":36,"publisher":"BMJ","issue":"6","funder":[{"DOI":"10.13039\/100000985","name":"Assisi Foundation of Memphis","doi-asserted-by":"publisher","award":["18-060"],"award-info":[{"award-number":["18-060"]}],"id":[{"id":"10.13039\/100000985","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2021,7,6]]},"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Mobile stroke units (MSUs) performance dependability and diagnostic yield of 16-slice, ultra-fast CT with auto-injection angiography (CTA) of the aortic arch\/neck\/circle of Willis has not been previously reported.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We performed a prospective observational study of the first-of-its kind MSU equipped with high resolution, 16-slice CT with multiphasic CTA. Field CT\/CTA was performed on all suspected stroke patients regardless of symptom severity or resolution. Performance dependability, efficiency and diagnostic yield over 365 days was quantified.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>1031 MSU emergency activations occurred; of these, 629 (61%) were disregarded with unrelated diagnoses, and 402 patients transported: 245 (61%) ischemic or hemorrhagic stroke, 17 (4%) transient ischemic attack, 140 (35%) other neurologic emergencies. Total time from non-contrast CT\/CTA start to images ready for viewing was 4.0 (IQR 3.5\u20134.5) min. Hemorrhagic stroke totaled 24 (10%): aneurysmal subarachnoid hemorrhage 3, hemorrhagic infarct 1, and 20 intraparenchymal hemorrhages (median intracerebral hemorrhage score was 2 (IQR 1\u20133), 4 (20%) spot sign positive). In 221 patients with ischemic stroke, 73 (33%) received alteplase with 31.5% treated within 60 min of onset. CTA revealed large vessel occlusion in 66 patients (30%) of which 9 (14%) were extracranial; 27 (41%) underwent thrombectomy with onset to puncture time averaging 141\u00b190 min (median 112 (IQR 90\u2013139) min) with full emergency department (ED) bypass. No imaging needed to be repeated for image quality; all patients were triaged correctly with no inter-hospital transfer required.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>MSU use of advanced imaging including multiphasic head\/neck CTA is feasible, offers high LVO yield and enables full ED bypass.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2021-017697","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T13:40:23Z","timestamp":1629898823000},"page":"623-627","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["High-resolution CT with arch\/neck\/head CT angiography on a mobile stroke unit"],"prefix":"10.1136","volume":"14","author":[{"given":"Anne W","family":"Alexandrov","sequence":"first","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam S","family":"Arthur","sequence":"additional","affiliation":[{"name":"Neurosurgery, UTHSC COM, Memphis, Tennessee, USA"},{"name":"Vascular Neurosurgery, Semmes-Murphey Neurologic and Spine Institute, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Bryndziar","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria M","family":"Swatzell","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Dusenbury","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keri","family":"Hardage","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"McCormick","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James P","family":"Rhudy","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Hossein Zadeh","family":"Maleki","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3710-544X","authenticated-orcid":false,"given":"Savdeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balaji","family":"Krishnaiah","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Nearing","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark N","family":"Rubin","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc D","family":"Malkoff","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"McKendry","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E Jeffrey","family":"Metter","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8871-1023","authenticated-orcid":false,"given":"Andrei V","family":"Alexandrov","sequence":"additional","affiliation":[{"name":"Neurology, UTHSC COM, Memphis, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"2025092912142882000_14.6.623.1","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1161\/STROKEAHA.119.025106","article-title":"Emergency department door-to-puncture time since 2014","volume":"50","author":"Czap","year":"2019","journal-title":"Stroke"},{"key":"2025092912142882000_14.6.623.2","doi-asserted-by":"crossref","unstructured":"Fassbender K , Davis S , Alexandrov AW . 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