{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:46:31Z","timestamp":1790621191955,"version":"4.1.0"},"reference-count":15,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2022,2,28]]},"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Flat detector computed tomography (FDCT) is widely used for periprocedural imaging in the angiography suite. Sine Spin FDCT (SFDCT) is the latest generation of cone beam CT using a double oblique trajectory for image acquisition to reduce artefacts and improve soft tissue brain imaging. This study compared the effective dose, image quality and diagnostic performance of the latest generation of SFDCT with multidetector CT (MDCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An anthropomorphic phantom equipped with MOSFET detectors was used to measure the effective dose of the new 7sDCT Sine Spin protocol on a latest generation biplane angiographic C-arm system. Diagnostic performance was evaluated on periprocedurally acquired SFDCT for depiction of anatomical details, detection of hemorrhage, and ischemia and was compared with preprocedurally acquired MDCT. Inter- and intra-rater correlation as well as sensitivity and specificity were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both modalities showed equal diagnostic performance in the supratentorial ventricular system. SFDCT provided inferior image quality in grey-white matter differentiation and infratentorial structures. Intraventricular, subarachnoid and parenchymal hemorrhages were diagnosed with a sensitivity of 83.3%, 84.2% and 75% and a specificity of 97.3%, 80.0% and 100%, respectively; early ischemic lesions with a sensitivity of 73.3% and specificity 94.7%. The effective dose measured for the 7sDCT Sine Spin protocol was 2\u2009mSv.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings confirm the high diagnostic sensitivity and specificity of SFDCT in detecting intracranial hemorrhage and early ischemic lesions. The delineation of grey-white matter differentiation and infratentorial structures remains a limiting factor. In comparison to previous studies, the new 7sDCT Sine Spin protocol showed a lower effective dose.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/neurintsurg-2021-018312","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T13:25:53Z","timestamp":1647955553000},"page":"292-297","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":25,"title":["Evaluation of Sine Spin flat detector CT imaging compared with multidetector CT"],"prefix":"10.1136","volume":"15","author":[{"given":"Valentina D","family":"Petroulia","sequence":"first","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9177-2289","authenticated-orcid":false,"given":"Johannes","family":"Kaesmacher","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5609-0998","authenticated-orcid":false,"given":"Eike I","family":"Piechowiak","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6167-3343","authenticated-orcid":false,"given":"Tomas","family":"Dobrocky","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M","family":"Pilgram-Pastor","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Gralla","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franca","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Mordasini","sequence":"additional","affiliation":[{"name":"Department for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"2025092911282690000_15.3.292.1","unstructured":"Kak AC , Slaney M . Principles of computerized tomographic imaging. IEEE Press, 1988."},{"key":"2025092911282690000_15.3.292.2","doi-asserted-by":"crossref","unstructured":"Strobel N , Meissner O , Boese J . 3D Imaging with flat-detector C-arm systems. In: Reiser MF , Becker CR , Nikolaou K , eds. Multislice CT. Berlin, Heidelberg: Springer, 2009: 33\u201351.","DOI":"10.1007\/978-3-540-33125-4_3"},{"key":"2025092911282690000_15.3.292.3","unstructured":"International Electrotechnical Commission . IEC 60601-2-43:2010\/AMD2:2019 Amendment 2 - Medical electrical equipment - Part 2-43: Particular requirements for the basic safety and essential performance of X-ray equipment for interventional procedures; 2019. https:\/\/webstore.iec.ch\/publication\/65930"},{"key":"2025092911282690000_15.3.292.4","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-019-02037-6"},{"key":"2025092911282690000_15.3.292.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-014-3136-7"},{"key":"2025092911282690000_15.3.292.6","unstructured":"ICRP . The 2007 recommendations of the International Commission on Radiological Protection. Ann ICRP 2 ICRP Publication; 2007. https:\/\/www.icrp.org\/docs\/ICRP_Publication_103-Annals_of_the_ICRP_37(2-4)-Free_extract.pdf"},{"key":"2025092911282690000_15.3.292.7","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2086"},{"key":"2025092911282690000_15.3.292.8","doi-asserted-by":"publisher","DOI":"10.1007\/s00062-015-0423-x"},{"key":"2025092911282690000_15.3.292.9","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5595"},{"key":"2025092911282690000_15.3.292.10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165794"},{"key":"2025092911282690000_15.3.292.11","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012866"},{"key":"2025092911282690000_15.3.292.12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/1747493019895655","article-title":"Flat-panel detector CT assessment in stroke to reduce times to intra-arterial treatment: a study of multiphase computed tomography angiography in the angiography suite to bypass conventional imaging","volume":"16","author":"Bouslama","year":"2021","journal-title":"Int J Stroke"},{"key":"2025092911282690000_15.3.292.13","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.018077"},{"key":"2025092911282690000_15.3.292.14","first-page":"1","article-title":"Flat panel CT scanning is helpful in predicting hemorrhagic transformation in acute ischemic stroke patients undergoing endovascular thrombectomy","volume":"2021","author":"Chen","year":"2021","journal-title":"Biomed Res Int"},{"key":"2025092911282690000_15.3.292.15","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-06891-w"}],"container-title":["Journal of NeuroInterventional Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/neurintsurg-2021-018312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T18:28:35Z","timestamp":1759170515000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnis.bmj.com\/lookup\/doi\/10.1136\/neurintsurg-2021-018312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,2,14]]},"published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1136\/neurintsurg-2021-018312"],"URL":"https:\/\/doi.org\/10.1136\/neurintsurg-2021-018312","relation":{},"ISSN":["1759-8478","1759-8486"],"issn-type":[{"value":"1759-8478","type":"print"},{"value":"1759-8486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]}}}