{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:20:18Z","timestamp":1759191618639,"version":"3.44.0"},"reference-count":17,"publisher":"BMJ","issue":"7","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"MIVI Neuroscience, Inc.","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J NeuroIntervent Surg"],"accepted":{"date-parts":[[2022,5,9]]},"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The Q Aspiration Catheter (MIVI Neuro) has demonstrated greater aspiration flow rates and ingestion forces compared with conventional catheters in vitro. The safety and performance of the Q Catheter was assessed using a direct aspiration first pass technique in patients with acute ischemic stroke at four neurointerventional centers in Spain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We included adult patients who underwent mechanical thrombectomy between March 2019 and March 2020 using the Q Catheter as first-line therapy. Performance endpoints included final successful revascularization of the target vessel (defined as modified thrombolysis in cerebral infarction (mTICI) grade 2B\/3), first pass revascularization, and overall Q Catheter revascularization. Safety endpoints were symptomatic intracranial hemorrhage (sICH), embolization to new territory (ENT), and procedural complications. Modified Rankin Scale (mRS) score and all-cause mortality were also assessed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Forty-five subjects were enrolled. The Q Catheter successfully navigated to the lesion in 95.5% (43\/45) of patients. Final successful mTICI 2B\/3 revascularization was achieved in 93.3% (42\/45), first pass mTICI 2B\/3 revascularization with the Q Catheter was 55.3% (21\/38), and overall with Q Catheter mTICI 2B\/3 revascularization was 65.8% (25\/38). Favorable clinical outcome of mRS 0\u20132 was achieved in 55.6% (25\/45). There were no cases of ENT. sICH and mortality rates were 2.2% (1\/45) and 13.3% (6\/45), respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In this multicenter, observational study, the Q Aspiration Catheter used as first-line therapy demonstrated a good and safe profile in terms of navigation, revascularization, and safety in patients with acute ischemic stroke.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/neurintsurg-2022-018649","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T13:26:37Z","timestamp":1654003597000},"page":"674-678","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Thrombectomy aspiration post-market study in acute stroke with the Q aspiration catheter: the TAPAS study"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7685-5588","authenticated-orcid":false,"given":"Mariano","family":"Espinosa de Rueda","sequence":"first","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario Virgen de la Arrixaca, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Ballenilla Marco","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E\u00f1aut","family":"Garmendia Lopetegui","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Universitario de Donostia, San Sebasti\u00e1n, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose M","family":"Pumar","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario de Santiago de Compostela, Santiago de Compostela, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquin","family":"Zamarro","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario Virgen de la Arrixaca, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanca","family":"Garc\u00eda-Villalba","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario Virgen de la Arrixaca, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"D\u00edaz-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario Virgen de la Arrixaca, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0345-2486","authenticated-orcid":false,"given":"Antonio","family":"Mosqueira","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario de Santiago de Compostela, Santiago de Compostela, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"L\u00fcttich","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Universitario de Donostia, San Sebasti\u00e1n, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose-Angel","family":"Larrea","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Universitario de Donostia, San Sebasti\u00e1n, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Parrilla","sequence":"additional","affiliation":[{"name":"Department of Interventional Neuroradiology, Hospital Cl\u00ednico Universitario Virgen de la Arrixaca, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"2025092911162408000_15.7.674.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00163-X"},{"key":"2025092911162408000_15.7.674.2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.9644"},{"key":"2025092911162408000_15.7.674.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30297-1"},{"key":"2025092911162408000_15.7.674.4","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013702"},{"key":"2025092911162408000_15.7.674.5","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2013-010713"},{"key":"2025092911162408000_15.7.674.6","doi-asserted-by":"publisher","DOI":"10.1177\/1591019915609170"},{"key":"2025092911162408000_15.7.674.7","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1093\/ons\/opy202","article-title":"The ANTRACK technique: employing a compliant balloon or stent retriever to advance a Large-Bore catheter to an occlusion during thrombectomy procedures in acute stroke patients","volume":"16","author":"Lin","year":"2019","journal-title":"Oper Neurosurg"},{"key":"2025092911162408000_15.7.674.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)08020-9"},{"key":"2025092911162408000_15.7.674.9","article-title":"Combined Approach to Stroke Thrombectomy Using a Novel Short Flexible Aspiration Catheter with a Stent Retriever : Preliminary Clinical Experience","author":"Remollo","year":"2021","journal-title":"Clin Neuroradiol"},{"key":"2025092911162408000_15.7.674.10","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012812"},{"key":"2025092911162408000_15.7.674.11","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/1591019918803962","article-title":"A direct aspiration first pass technique with the new Arc catheter for thrombectomy of large vessel occlusion strokes: a multicenter study","volume":"25","author":"De Marini","year":"2019","journal-title":"Interv Neuroradiol"},{"key":"2025092911162408000_15.7.674.12","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s00270-018-2093-y","article-title":"Endovascular stroke therapy with a novel 6-French aspiration catheter","volume":"42","author":"Bretzner","year":"2019","journal-title":"Cardiovasc Intervent Radiol"},{"key":"2025092911162408000_15.7.674.13","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A6074"},{"key":"2025092911162408000_15.7.674.14","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s11604-021-01090-z","article-title":"Direct aspiration thrombectomy experience with the Sofia 6F catheter in acute ischemic stroke","volume":"39","author":"Bilgin","year":"2021","journal-title":"Jpn J 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