{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T09:10:04Z","timestamp":1716455404597},"reference-count":6,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:p><jats:bold>Aims:<\/jats:bold>To explore relations between exposure to fungal \u03b1-amylase and the risk of new work related respiratory symptoms or sensitisation.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>A prospective cohort study among 300 bakers and millers was followed up for a maximum of seven years. Exposure to \u03b1-amylase was estimated by air measurements and questionnaires and classified into three categories. Symptoms were recorded with a self-administered questionnaire and skin sensitisation assessed using skin prick test (SPT).<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>There were 36 new cases of chest symptoms, 86 of eyes\/nose symptoms, and 24 of a positive SPT to \u03b1-amylase. There were exposure-response relations for chest and eyes\/nose symptoms and for sensitisation, and a significantly increased prevalence ratio for chest symptoms in the highest exposure category.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold>A reduction in \u03b1-amylase exposure is likely to reduce the risk for respiratory morbidity in bakery workers.<\/jats:p>","DOI":"10.1136\/oem.2002.006395","type":"journal-article","created":{"date-parts":[[2004,5,18]],"date-time":"2004-05-18T17:32:59Z","timestamp":1084901579000},"page":"551-553","source":"Crossref","is-referenced-by-count":18,"title":["Exposure-response relations for work related respiratory symptoms and sensitisation in a cohort exposed to \u03b1-amylase: Table 1"],"prefix":"10.1136","volume":"61","author":[{"given":"J","family":"Brisman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M J","family":"Nieuwenhuijsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K M","family":"Venables","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Putcha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A J N","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2004,5,18]]},"reference":[{"key":"2024052222242727000_61.6.551.1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199812)34:6<529::AID-AJIM1>3.0.CO;2-I"},{"key":"2024052222242727000_61.6.551.2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.1.8680668"},{"key":"2024052222242727000_61.6.551.3","doi-asserted-by":"publisher","DOI":"10.1136\/oem.56.3.197"},{"key":"2024052222242727000_61.6.551.4","doi-asserted-by":"publisher","DOI":"10.1093\/annhyg\/45.2.97"},{"key":"2024052222242727000_61.6.551.5","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1136\/oem.56.11.735","volume":"56","year":"1999","journal-title":"Occup Environ Med"},{"key":"2024052222242727000_61.6.551.6","doi-asserted-by":"publisher","DOI":"10.1093\/annhyg\/44.6.421"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.2002.006395","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T05:50:22Z","timestamp":1716443422000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.2002.006395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5,18]]},"references-count":6,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2004,5,18]]},"published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1136\/oem.2002.006395"],"URL":"https:\/\/doi.org\/10.1136\/oem.2002.006395","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5,18]]}}}