{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T11:41:15Z","timestamp":1793187675137,"version":"4.5.0"},"reference-count":36,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold>Natural rubber latex allergy can cause skin and respiratory symptoms The aim of this study was to evaluate the prevalence and incidence of latex related symptoms and sensitisation among a large group of healthcare workers in Trieste hospitals, followed for three years before and after the introduction of powder-free gloves with low latex release.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>In the years 1997\u201399 the authors evaluated 1040 healthcare workers exposed to latex allergen for latex related symptoms and sensitisation by means of a questionnaire, a medical examination, skin prick tests, and IgE specific antibody assay. The second evaluation was carried out in the years 2000\u201302, subsequent to the changeover to a powder-free environment.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>Glove related symptoms were seen in 21.8% of the nurses (227), mostly consisting of mild dermatitis: 38 (3.6%) complaining of contact urticaria and 24 (2.3%) of asthma and\/or rhinitis. These symptoms were significantly related to skin prick tests positive to latex (OR\u200a=\u200a9.70; 95% CI 5.5 to 17) and to personal atopy (OR\u200a=\u200a2.29; 95% CI 1.6 to 3.2). Follow up was completed in 960 subjects (92.3%): 19 new subjects (2.4%) complained of itching erythema when using gloves, but none was prick positive to latex. Symptoms significantly improved and in most cases disappeared (p&lt;0.0001).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold>Simple measures such as the avoidance of unnecessary glove use, the use of non-powdered latex gloves by all workers, and use of non-latex gloves by sensitised subjects can stop the progression of latex symptoms and can avoid new cases of sensitisation.<\/jats:p>","DOI":"10.1136\/oem.2003.011460","type":"journal-article","created":{"date-parts":[[2006,1,18]],"date-time":"2006-01-18T23:18:40Z","timestamp":1137626320000},"page":"121-125","source":"Crossref","is-referenced-by-count":82,"title":["Latex allergy: a follow up study of 1040 healthcare workers"],"prefix":"10.1136","volume":"63","author":[{"given":"F","family":"Larese 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