{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T18:28:43Z","timestamp":1790533723720,"version":"4.1.0"},"reference-count":40,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p><jats:bold>Objective:<\/jats:bold>To evaluate the association between air pollutants and the occurrence of acute stroke from 10-year population-based study.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>The daily stroke count was obtained from Dijon Stroke Register between March 1994 and December 2004. The register recorded all first-ever strokes among residents of Dijon (150 000 inhabitants) in France, using standard diagnostic criteria. Pollutant concentrations (SO<jats:sub>2<\/jats:sub>, CO, NO<jats:sub>2,<\/jats:sub>O<jats:sub>3<\/jats:sub>and PM<jats:sub>10<\/jats:sub>) were measured hourly. A bi-directional case-crossover design was used to examine the association between air pollutant and stroke onset. The conditional logistic regression model included the meteorological parameters (temperature, relative humidity), influenza epidemics and holidays.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>The authors collected 493 large artery infarcts, 397 small artery infarcts, 530 cardio-embolic infarcts, 67 undeterminate infarcts, 371 transient ischaemic attacks and 220 haemorrhagic strokes. For single-pollutant model and for a 10 mg\/m<jats:sup>3<\/jats:sup>increase of O<jats:sub>3<\/jats:sub>exposure, a positive association was observed only in men, over 40 years of age, between ischaemic stroke occurrence and O<jats:sub>3<\/jats:sub>levels with 1-day lag, (OR 1.133, 95% CI 1.052 to 1.220) and 0-day lag (OR 1.058, 95% CI 0.987 to 1.134). No significant associations were found for haemorrhagic stroke. In two-pollutant models, the effects of O<jats:sub>3<\/jats:sub>remained significant after each of the other pollutants were included in the model, in particular with PM<jats:sub>10<\/jats:sub>. A significant association was observed for ischaemic strokes of large arteries (p\u200a=\u200a0.02) and for transient ischaemic attacks (p\u200a=\u200a0.01). Moreover, the authors found an exposure-response relations between O<jats:sub>3<\/jats:sub>exposure and ischaemic stroke (test for trend, p\u200a=\u200a0.01). An increase in association in men with several cardiovascular risk factors (smoker, dyslipidemia and hypertension) was also observed.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold>These observational data argue for an association between ischaemic stroke occurrence and O<jats:sub>3<\/jats:sub>pollution levels; these results still need to be confirmed by other studies.<\/jats:p>","DOI":"10.1136\/oem.2006.029306","type":"journal-article","created":{"date-parts":[[2007,4,5]],"date-time":"2007-04-05T00:25:02Z","timestamp":1175732702000},"page":"439-445","source":"Crossref","is-referenced-by-count":130,"title":["Short-term effects of ozone air pollution on ischaemic stroke occurrence: a case-crossover analysis from a 10-year population-based study in Dijon, France"],"prefix":"10.1136","volume":"64","author":[{"given":"J B","family":"Henrotin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J P","family":"Besancenot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Bejot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Giroud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2007,4,4]]},"reference":[{"key":"2024052223262319000_64.7.439.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200012143432401"},{"key":"2024052223262319000_64.7.439.2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.56.10.773"},{"key":"2024052223262319000_64.7.439.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.314.7095.1658"},{"key":"2024052223262319000_64.7.439.4","doi-asserted-by":"publisher","DOI":"10.1136\/oem.59.1.30"},{"key":"2024052223262319000_64.7.439.5","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.2105\/AJPH.86.9.1273","volume":"86","year":"1996","journal-title":"Am J Public Health"},{"key":"2024052223262319000_64.7.439.6","doi-asserted-by":"publisher","DOI":"10.1136\/jech.55.1.57"},{"key":"2024052223262319000_64.7.439.7","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1289\/ehp.99107629","volume":"107","year":"1999","journal-title":"Environ Health Perspect"},{"key":"2024052223262319000_64.7.439.8","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2003.016386"},{"key":"2024052223262319000_64.7.439.9","doi-asserted-by":"publisher","DOI":"10.1539\/joh.45.119"},{"key":"2024052223262319000_64.7.439.10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000154546.32135.6E"},{"key":"2024052223262319000_64.7.439.11","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000128587.30041.C8"},{"key":"2024052223262319000_64.7.439.12","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000026865.52610.5B"},{"key":"2024052223262319000_64.7.439.13","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.02110187"},{"key":"2024052223262319000_64.7.439.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000101750.77547.11"},{"key":"2024052223262319000_64.7.439.15","doi-asserted-by":"publisher","DOI":"10.1539\/joh.45.321"},{"key":"2024052223262319000_64.7.439.16","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000095564.33543.64"},{"key":"2024052223262319000_64.7.439.17","doi-asserted-by":"publisher","DOI":"10.1136\/oem.54.2.108"},{"key":"2024052223262319000_64.7.439.18","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000189687.78760.47"},{"key":"2024052223262319000_64.7.439.19","doi-asserted-by":"publisher","DOI":"10.1136\/oem.54.8.535"},{"key":"2024052223262319000_64.7.439.20","doi-asserted-by":"publisher","DOI":"10.1136\/jech.44.4.321"},{"key":"2024052223262319000_64.7.439.21","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)21027-0"},{"key":"2024052223262319000_64.7.439.22","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/20.4.892"},{"key":"2024052223262319000_64.7.439.23","unstructured":"World Health Organization. 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