{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T02:31:33Z","timestamp":1725849093651},"reference-count":43,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>An inception cohort of trades' apprentices had rapid declines in lung function (forced expiratory volume in 1\u2005s (FEV<jats:sub>1<\/jats:sub>)) and rapid increases in bronchial responsiveness (\u2191BR) over the first 2\u2005years of employment. We used physician visit data to assess respiratory health over the following 13\u2005years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Construction painter, electrician, insulator and machinist apprentices beginning at a British Columbia trade school in 1988 were invited to participate and were followed up 2\u2005years later. Subjects were linked to provincial medical databases to examine physician visits for asthma and other respiratory illnesses for the 13\u2005years following. Multivariable models with rapid decline in FEV<jats:sub>1<\/jats:sub>and rapid increase in BR from years 1 to 3 were constructed. Respiratory symptoms were also examined as predictors of visit rates and meeting a case definition (for asthma or other respiratory illness).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cohort included 281 apprentices (97% are men). Sixteen subjects met the asthma case definition (\u22652 visits coded as asthma in 1\u2005year) and 20 met the other respiratory illness case definition (\u22653 visits for bronchitis, emphysema, respiratory symptoms in 1\u2005year). In models controlling for demographic factors and smoking, subjects with bronchitis symptoms at baseline were more likely to develop other respiratory illness during follow-up (RR 4.4, 95% CI 1.6 to 11.9). Apprentices who developed asthma symptoms over the first 2\u2005years were approximately six times more likely to become asthma cases (95% CI 1.9 to 18.8). Those with a rapid increase in BR were at increased risk of becoming asthma cases (RR 5.5, 95% CI 1.9 to 16.1), as well as having higher asthma visit rates (RR 6.5). Subjects with rapid decline in FEV<jats:sub>1<\/jats:sub>were 3.2 times more likely to become asthma cases (95% CI 0.8 to 12.1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Changes in respiratory health early in adulthood, especially increased BR, are associated with respiratory physician visits. These findings are important for workplace screening and prevention and also suggest that physician visit databases are promising research tools in respiratory epidemiology.<\/jats:p><\/jats:sec>","DOI":"10.1136\/oem.2008.042663","type":"journal-article","created":{"date-parts":[[2009,8,11]],"date-time":"2009-08-11T00:13:47Z","timestamp":1249949627000},"page":"237-243","source":"Crossref","is-referenced-by-count":5,"title":["Early changes in respiratory health in trades' apprentices and physician visits for respiratory illnesses later in life"],"prefix":"10.1136","volume":"67","author":[{"given":"C E","family":"Peters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Demers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Sehmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Karlen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S M","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2009,8,9]]},"reference":[{"key":"2024052300030480000_67.4.237.1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.01.17509820"},{"key":"2024052300030480000_67.4.237.2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.2.493"},{"key":"2024052300030480000_67.4.237.3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1164\/ajrccm.163.3.2008084","article-title":"Rapid declines in FEV1 and subsequent respiratory symptoms, illnesses, and mortality in coal miners in the United States","volume":"163","author":"Beeckman","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"2024052300030480000_67.4.237.4","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200508-1344OC"},{"key":"2024052300030480000_67.4.237.5","first-page":"929","article-title":"Longitudinal and cross sectional analyses of exposure to coal mine dust and pulmonary function in new miners","volume":"50","author":"Seixas","year":"1993","journal-title":"Br J Ind Med"},{"key":"2024052300030480000_67.4.237.6","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2005.020271"},{"key":"2024052300030480000_67.4.237.7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.1.62"},{"key":"2024052300030480000_67.4.237.8","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1164\/ajrccm\/146.4.855","article-title":"Longitudinal lung function decline in subjects with respiratory symptoms","volume":"146","author":"Sherman","year":"1992","journal-title":"Am Rev Respir Dis"},{"key":"2024052300030480000_67.4.237.9","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200603-381OC"},{"key":"2024052300030480000_67.4.237.10","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00044804"},{"key":"2024052300030480000_67.4.237.11","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.059436"},{"key":"2024052300030480000_67.4.237.12","doi-asserted-by":"publisher","DOI":"10.1097\/01.jom.0000214351.18905.48"},{"key":"2024052300030480000_67.4.237.13","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20050"},{"key":"2024052300030480000_67.4.237.14","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1164\/ajrccm.163.4.2008011","article-title":"Incidence and host determinants of probable occupational asthma in apprentices exposed to laboratory animals","volume":"163","author":"Gautrin","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"2024052300030480000_67.4.237.15","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1164\/ajrccm\/146.4.878","article-title":"Methacholine responsiveness, smoking, and atopy as risk factors for accelerated FEV1 decline in male working populations","volume":"146","author":"Frew","year":"1992","journal-title":"Am Rev Respir Dis"},{"key":"2024052300030480000_67.4.237.16","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.151.5.7735588"},{"key":"2024052300030480000_67.4.237.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)10041-1"},{"key":"2024052300030480000_67.4.237.18","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/141.1.2"},{"key":"2024052300030480000_67.4.237.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02815-4"},{"key":"2024052300030480000_67.4.237.20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3109\/02770909409044824","article-title":"Longitudinal measurement of airway hyperresponsiveness in selected subjects with persisting pulmonary symptoms","volume":"31","author":"Hopp","year":"1994","journal-title":"J Asthma"},{"key":"2024052300030480000_67.4.237.21","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61164-7"},{"key":"2024052300030480000_67.4.237.22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1164\/ajrccm.159.1.9804071","article-title":"Change in airway responsiveness among apprentices exposed to metalworking fluids","volume":"159","author":"Kennedy","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"2024052300030480000_67.4.237.23","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.1.151"},{"key":"2024052300030480000_67.4.237.24","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.1.16"},{"key":"2024052300030480000_67.4.237.25","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1155\/2004\/976852","article-title":"Identifying children with persistent asthma from health care administrative records","volume":"11","author":"Kozyrskyj","year":"2004","journal-title":"Can Respir J"},{"key":"2024052300030480000_67.4.237.26","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199709)32:3<275::AID-AJIM14>3.0.CO;2-S"},{"key":"2024052300030480000_67.4.237.27","first-page":"7","article-title":"Epidemiology standardization project: recommended respiratory disease questionnaire for use with adults and children in epidemiology research","volume":"118","author":"Ferris","year":"1978","journal-title":"Am Rev Respir Dis"},{"key":"2024052300030480000_67.4.237.28","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200203-238OC"},{"key":"2024052300030480000_67.4.237.29","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"2024052300030480000_67.4.237.30","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(79)90158-1"},{"key":"2024052300030480000_67.4.237.31","first-page":"270","article-title":"Creating a population-based linked health database: a new resource for health services research","volume":"89","author":"Chamberlayne","year":"1998","journal-title":"Can J Publ Hlth"},{"key":"2024052300030480000_67.4.237.32","unstructured":"World Health Organization. International classification of diseases. 9th rev. Geneva, WHO, 1987."},{"key":"2024052300030480000_67.4.237.33","unstructured":"BC Health Services. Guidelines and protocols advisory committee. Diagnosis and management of asthma. Victoria, BC: BC Health Services, 2003. Clinical Practices Guideline Publication No. 058."},{"key":"2024052300030480000_67.4.237.34","doi-asserted-by":"publisher","DOI":"10.1002\/nur.20093"},{"key":"2024052300030480000_67.4.237.35","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/144.5.1202"},{"key":"2024052300030480000_67.4.237.36","first-page":"101","article-title":"Surveillance for occupational asthma","volume":"6","author":"Balmes","year":"1991","journal-title":"Occup Med (Lond)"},{"key":"2024052300030480000_67.4.237.37","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2008.041079"},{"key":"2024052300030480000_67.4.237.38","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199706)31:6<756::AID-AJIM13>3.0.CO;2-X"},{"key":"2024052300030480000_67.4.237.39","doi-asserted-by":"publisher","DOI":"10.1136\/thx.43.3.200"},{"key":"2024052300030480000_67.4.237.40","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199711)32:5<450::AID-AJIM4>3.0.CO;2-W"},{"key":"2024052300030480000_67.4.237.41","doi-asserted-by":"publisher","DOI":"10.1186\/1476-069X-2-10"},{"key":"2024052300030480000_67.4.237.42","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.22.1.213"},{"key":"2024052300030480000_67.4.237.43","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.056093"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.2008.042663","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T08:34:36Z","timestamp":1716453276000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.2008.042663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,9]]},"references-count":43,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2010,4,1]]},"published-print":{"date-parts":[[2010,4]]}},"alternative-id":["10.1136\/oem.2008.042663"],"URL":"https:\/\/doi.org\/10.1136\/oem.2008.042663","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,9]]}}}