{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T18:41:31Z","timestamp":1775068891457,"version":"3.50.1"},"reference-count":40,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"accepted":{"date-parts":[[2010,2,11]]},"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Acoustic neuroma is a benign tumour accounting for approximately 6\u201310% of all intracranial tumours and occurs mainly in patients aged \u226550\u2005years. Our aim was to investigate a wide range of occupational exposures, individual occupational titles and socioeconomic status (SES) as potential risk factors for acoustic neuroma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a population-based case\u2013control study of 793 acoustic neuroma cases identified through the Swedish Cancer Registry and 101\u2008762 randomly selected controls. Information on SES and occupation was obtained from censuses and linked to job-exposure matrices. Logistic regression was used to estimate ORs and calculate 95% CIs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>An increased OR was seen for mercury exposure &lt;10\u2005years before the reference year (OR 2.9; 95% CI 1.2 to 6.8), and a more modest association for benzene exposure (OR 1.8; 95% CI: 1.0 to 3.2) \u226510\u2005years before the reference year. We observed a threefold increased risk for females working as tailors and dressmakers \u226510\u2005years before the reference year, and a more than threefold significantly elevated OR for those working as truck and conveyor operators &lt;10\u2005years before the reference year. We found no convincing evidence that SES is related to disease development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We observed an increased risk of acoustic neuroma associated with occupational exposure to mercury, benzene and textile dust. Men working as truck and conveyor operators &lt;10\u2005years before the reference year had the highest increased risk of acoustic neuroma, but it is unclear what in those occupations might contribute to disease development. Our study also suggested an association between acoustic neuroma and being a class teacher or policeman. However, these findings should be further investigated to exclude the possibility of detection bias.<\/jats:p><\/jats:sec>","DOI":"10.1136\/oem.2009.047886","type":"journal-article","created":{"date-parts":[[2010,6,28]],"date-time":"2010-06-28T00:14:24Z","timestamp":1277684064000},"page":"766-771","source":"Crossref","is-referenced-by-count":16,"title":["Occupational exposures and risk of acoustic neuroma"],"prefix":"10.1136","volume":"67","author":[{"given":"Michaela","family":"Prochazka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Feychting","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Ahlbom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin G","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gun","family":"Nise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Plato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith A","family":"Schwartzbaum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulla M","family":"Forss\u00e9n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,6,27]]},"reference":[{"key":"2024052300172604000_67.11.766.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198810203191601"},{"key":"2024052300172604000_67.11.766.2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.20.1555"},{"key":"2024052300172604000_67.11.766.3","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1989.163"},{"key":"2024052300172604000_67.11.766.4","first-page":"690","article-title":"Incidence of vestibular schwannoma in Denmark, 1977\u20131995","volume":"21","author":"Howitz","year":"2000","journal-title":"Am J Otol"},{"key":"2024052300172604000_67.11.766.5","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyg051"},{"key":"2024052300172604000_67.11.766.6","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000142519.00772.bf"},{"key":"2024052300172604000_67.11.766.7","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20251"},{"key":"2024052300172604000_67.11.766.8","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj044"},{"key":"2024052300172604000_67.11.766.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2007.05.008"},{"key":"2024052300172604000_67.11.766.10","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.10363"},{"key":"2024052300172604000_67.11.766.11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1289\/ehp.01109193","article-title":"Paternal occupational exposures and childhood cancer","volume":"109","author":"Feychting","year":"2001","journal-title":"Environ Health Perspect"},{"key":"2024052300172604000_67.11.766.12","unstructured":"Statistiska Centralbyr\u00e5n, (National Central Bureau of Statistics). Systematisk f\u00f6rteckning \u00f6ver yrken. Folk och bostadsr\u00e4kningen (in Swedish). Stockholm: Statistiska Centralbyr\u00e5n, (National Central Bureau of Statistics), 1975."},{"key":"2024052300172604000_67.11.766.13","unstructured":"Statistiska Centralbyr\u00e5n, (National Central Bureau of Statistics). Swedish Standard Industrial Classification of all Economic Activities (SNI). Second edition of the 1969 standard. Meddelanden i samordningsfr\u00e5gor, Stockholm: Statistiska Centralbyr\u00e5n, (National Central Bureau of Statistics), 1977:9."},{"key":"2024052300172604000_67.11.766.14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.5271\/sjweh.48","article-title":"Fiber exposure assessment in the Swedish rock wool and slag wool production industry in 1938\u20131990","volume":"21","author":"Plato","year":"1995","journal-title":"Scand J Work Environ Health"},{"key":"2024052300172604000_67.11.766.15","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/ajim.4700160212","article-title":"Industry-related urothelial carcinogens: application of a job-exposure matrix to census data","volume":"16","author":"Steineck","year":"1989","journal-title":"Am J Ind Med"},{"key":"2024052300172604000_67.11.766.16","first-page":"372","article-title":"Deaths and tumours among rotogravure printers exposed to toluene","volume":"47","author":"Svensson","year":"1990","journal-title":"Br J Ind Med"},{"issue":"Suppl 1","key":"2024052300172604000_67.11.766.17","first-page":"1","article-title":"Neuropsychiatric function of housepainters with previous long-term heavy exposure to organic solvents","volume":"21","author":"Lundberg","year":"1995","journal-title":"Scand J Work Environ Health"},{"key":"2024052300172604000_67.11.766.18","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700230312"},{"key":"2024052300172604000_67.11.766.19","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqi135"},{"key":"2024052300172604000_67.11.766.20","doi-asserted-by":"publisher","DOI":"10.1177\/074823379901500504"},{"key":"2024052300172604000_67.11.766.21","unstructured":"WHO. World Health Organization\/International Program on Chemical Safety (WHO\/IPCS). Elemental mercury and inorganic mercury compounds: human health aspects, Geneva: World Health Organization, International Program on Chemical Safety, 2003."},{"key":"2024052300172604000_67.11.766.22","first-page":"253","article-title":"Occupational risks for intracranial gliomas in Sweden","volume":"78","author":"McLaughlin","year":"1987","journal-title":"J Natl Cancer Inst"},{"key":"2024052300172604000_67.11.766.23","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.10107"},{"key":"2024052300172604000_67.11.766.24","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1289\/ehp.6704","article-title":"The asbestos cancer epidemic","volume":"112","author":"LaDou","year":"2004","journal-title":"Environ Health Perspect"},{"key":"2024052300172604000_67.11.766.25","doi-asserted-by":"publisher","DOI":"10.1097\/01.jom.0000165747.95801.c5"},{"key":"2024052300172604000_67.11.766.26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1982.tb50380.x"},{"key":"2024052300172604000_67.11.766.27","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20934"},{"key":"2024052300172604000_67.11.766.28","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-2797(03)00037-1"},{"key":"2024052300172604000_67.11.766.29","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000082001.05563.e0"},{"key":"2024052300172604000_67.11.766.30","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-1057"},{"key":"2024052300172604000_67.11.766.31","doi-asserted-by":"publisher","DOI":"10.1006\/rtph.2000.1410"},{"key":"2024052300172604000_67.11.766.32","doi-asserted-by":"crossref","first-page":"178","DOI":"10.5271\/sjweh.996","article-title":"Brain tumors and occupational exposures in a cohort of female textile workers in Shanghai, China","volume":"32","author":"Gold","year":"2006","journal-title":"Scand J Work Environ Health"},{"key":"2024052300172604000_67.11.766.33","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm217"},{"key":"2024052300172604000_67.11.766.34","doi-asserted-by":"publisher","DOI":"10.3109\/02841868409136026"},{"issue":"Suppl 2","key":"2024052300172604000_67.11.766.35","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1093\/ije\/22.Supplement_2.S57","article-title":"Retrospective evaluation of occupational exposures in population-based case-control studies: general overview with special attention to job exposure matrices","volume":"22","author":"Bouyer","year":"1993","journal-title":"Int J Epidemiol"},{"key":"2024052300172604000_67.11.766.36","first-page":"174","article-title":"Growth rate of acoustic neuromas","volume":"10","author":"Valvassori","year":"1989","journal-title":"Am J Otol"},{"key":"2024052300172604000_67.11.766.37","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1288\/00005537-199409000-00011","article-title":"The natural history of untreated acoustic neuromas","volume":"104","author":"Strasnick","year":"1994","journal-title":"Laryngoscope"},{"key":"2024052300172604000_67.11.766.38","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199701000-00001"},{"key":"2024052300172604000_67.11.766.39","first-page":"12","article-title":"Acoustic neuroma: clinical aspects, audiovestibular assessment, diagnostic delay, and growth rate","volume":"11","author":"Thomsen","year":"1990","journal-title":"Am J Otol"},{"key":"2024052300172604000_67.11.766.40","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(84)90004-2"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.2009.047886","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T08:53:21Z","timestamp":1716454401000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.2009.047886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,27]]},"references-count":40,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2010,10,19]]},"published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1136\/oem.2009.047886"],"URL":"https:\/\/doi.org\/10.1136\/oem.2009.047886","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,27]]}}}