{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T07:06:15Z","timestamp":1765177575343},"reference-count":33,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"accepted":{"date-parts":[[2011,3,22]]},"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate exposures, respiratory symptoms, lung function and exposure\u2013response relationships among aluminium cast-house workers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross-sectional study was conducted among 182 workers. Exposure data were used to model exposure to irritants. Lung function and questionnaire data on respiratory symptoms were compared to a general population sample and an internal reference group. Blood samples were taken from 156 workers to examine total IgE, eosinophils and sensitisation to common allergens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Average daily mean exposure to inhalable dust, metals, hydrogen fluoride, fluoride salts and sulphur dioxide was relatively low compared to reference values. Airflow patterns in the hall were disturbed regularly and resulted in pot emissions with high concentrations of fluorides. Peak exposures to chlorine gas occurred intermittently due to production process disturbances. Workers reported significantly more respiratory symptoms (continuous trouble with breathing (prevalence ratio (PR) 2.5; 95% CI 1.2 to 5.3), repeated trouble with breathing (PR 1.8; 95% CI 1.1 to 3.0), wheezing (PR 1.4; 95% CI 1.1 to 1.8), asthma attack (ever) (PR 2.8; 95% CI 1.7 to 4.6) and doctor diagnosed asthma (PR 2.6; 95% CI 1.5 to 4.4). Regression analysis showed significantly lower FEV<jats:sub>1<\/jats:sub>values (\u2212195\u2005ml) and FVC values (\u2212142\u2005ml) compared to a general population sample. Lung function did not differ between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This epidemiological study suggests cast-house workers in the aluminium industry are exposed to respiratory hazards. Exposure\u2013response relationships could not be demonstrated but this study supports preventive measures in the work environment with a focus on (peak) exposures to irritants.<\/jats:p><\/jats:sec>","DOI":"10.1136\/oem.2010.062349","type":"journal-article","created":{"date-parts":[[2011,4,15]],"date-time":"2011-04-15T00:36:44Z","timestamp":1302827804000},"page":"876-882","source":"Crossref","is-referenced-by-count":15,"title":["A cross-sectional study of exposures, lung function and respiratory symptoms among aluminium cast-house workers"],"prefix":"10.1136","volume":"68","author":[{"given":"F G B G J","family":"van Rooy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Houba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Stigter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V A C","family":"Zaat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M M","family":"Zengeni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Rooyackers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H E","family":"Boers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D J J","family":"Heederik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2011,4,14]]},"reference":[{"key":"2024052300435391000_68.12.876.1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07010165"},{"key":"2024052300435391000_68.12.876.2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.49.10.984"},{"key":"2024052300435391000_68.12.876.3","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1183\/09031936.94.07050888","article-title":"Bronchial responsiveness and decline in FEV1 in aluminium potroom workers","volume":"7","author":"S\u00f8yseth","year":"1994","journal-title":"Eur Respir J"},{"key":"2024052300435391000_68.12.876.4","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1164\/ajrccm.150.6.7952639","article-title":"Aluminium potroom asthma confirmed by monitoring of forced expiratory volume in one second","volume":"150","author":"Desjardins","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"2024052300435391000_68.12.876.5","doi-asserted-by":"publisher","DOI":"10.1007\/s004200050250"},{"key":"2024052300435391000_68.12.876.6","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1164\/arrd.1983.127.4.465","article-title":"Epidemiologic health study of workers in an aluminum smelter in British Columbia. 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