{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:48:30Z","timestamp":1791280110192,"version":"4.1.0"},"reference-count":30,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occupational and Environmental Medicine"],"published-print":{"date-parts":[[1992,11,1]]},"DOI":"10.1136\/oem.49.11.791","type":"journal-article","created":{"date-parts":[[2008,12,17]],"date-time":"2008-12-17T00:14:48Z","timestamp":1229472888000},"page":"791-798","source":"Crossref","is-referenced-by-count":14,"title":["A case-control study of motor neurone disease: its relation to heritability, and occupational exposures, particularly to solvents."],"prefix":"10.1136","volume":"49","author":[{"given":"L G","family":"Gunnarsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Bodin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Soderfeldt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Axelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1136\/jnnp.53.12.1043","article-title":"Clinical features and associations of 560 cases of motor neurone disease","volume":"53","author":"Li, T.-M.; Alberman, E.; Swash, M.","year":"1990","unstructured":"Li T-M, Alberman E, Swash M. Clinical features and associations of 560 cases of motor neurone disease. J Neurol Neurosurg Psychiatry 1990;53:1043-5.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000110854","article-title":"Motor neuron disease and heavy manual labor: An epidemiologic survey of Varmland county, Sweden","volume":"3","author":"Gunnarsson, L.-G.; Palm, R.","year":"1984","unstructured":"Gunnarsson L-G, Palm R. Motor neuron disease and heavy manual labor: An epidemiologic survey of Varmland county, Sweden. Neuroepidemiology 1984;3:195-206.","journal-title":"Neuroepidemiology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1001\/archneur.1978.00500340014003","article-title":"Amyotrophic lateral sclerosis, clinical features and prognosis","volume":"35","author":"Rosen, A.D.","year":"1978","unstructured":"Rosen AD. Amyotrophic lateral sclerosis, clinical features and prognosis. Arch Neurol 1978;35:638-42.","journal-title":"Arch Neurol"},{"issue":"3","key":"ref_4","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1017\/S0317167100037732","article-title":"Guam ALS\/parkinsonism-dementia: a long latency neurotoxic disorder caused by \"slow toxin(s)\"","volume":"14","author":"Spencer, P.S.","year":"1987","unstructured":"Spencer PS. Guam ALS\/parkinsonism-dementia: a long latency neurotoxic disorder caused by \"slow toxin(s)\" in food. Can J Neurol Sci 1987;14(suppl 3):347-57.","journal-title":"in food. Can J Neurol Sci"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1212\/WNL.35.2.193","article-title":"Disappearance of high-incidence ALS and parkinsonism-dementia on Guam","volume":"35","author":"Garruto, R.M.; Yanagihara, R.; Gajdusek, C.","year":"1985","unstructured":"Garruto RM, Yanagihara R, Gajdusek C. Disappearance of high-incidence ALS and parkinsonism-dementia on Guam. Neurology 1985;35:193-8.","journal-title":"Neurology"},{"key":"ref_6","first-page":"46","article-title":"Theoretical epidemiology","author":"Miettinen, O.S.","year":"1985","unstructured":"Miettinen OS. Theoretical epidemiology. 1st ed. New York: John Wiley 1985:46-83.","edition":"1st ed"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1212\/WNL.17.10.1011","article-title":"Multiple sclerosis and amyotrophic lateral scerosis in Mississippi","volume":"17","author":"Breland, A.E.; Currier, R.D.","year":"1967","unstructured":"Breland AE, Currier RD. Multiple sclerosis and amyotrophic lateral scerosis in Mississippi. Neurology 1967;17:1011-6.","journal-title":"Neurology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1136\/jnnp.33.6.877","article-title":"Motor neuron disease and exposure to lead","volume":"33","author":"Campbell, A.M.G.; Williams, E.R.; Barltrop, D.","year":"1970","unstructured":"Campbell AMG, Williams ER, Barltrop D. Motor neuron disease and exposure to lead. J Neurol Neurosurg Psychiatry 1970;33:877-85.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1136\/jnnp.46.11.1041","article-title":"Antecedent events in motor neuron disease","volume":"46","author":"Gawel, M.; Zaiwalla, Z.; Clifford Rose, F.","year":"1983","unstructured":"Gawel M, Zaiwalla Z, Clifford Rose F. Antecedent events in motor neuron disease. J Neurol Neurosurg Psychiatry 1983;46: 1041-3.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1600-0404.1983.tb04543.x","article-title":"Amyotrophic lateral sclerosis in middle-Finland: an epidemiological study","volume":"67","author":"Murros, K.; Fogelholm, R.","year":"1983","unstructured":"Murros K, Fogelholm R. Amyotrophic lateral sclerosis in middle-Finland: an epidemiological study. Acta Neurol Scand 1983;67:41-7.","journal-title":"Acta Neurol Scand"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1600-0404.1987.tb07909.x","article-title":"Trauma and amyotrophic lateral sclerosis: A report of 78 patients","volume":"75","author":"Gallagher, J.P.; Sanders, M.","year":"1987","unstructured":"Gallagher JP, Sanders M. Trauma and amyotrophic lateral sclerosis: A report of 78 patients. Acta Neurol Scand 1987;75: 145-50.","journal-title":"Acta Neurol Scand"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0303-8467(87)80074-4","article-title":"Results of a questionnaire in 100 ALS patients and 100 control cases","volume":"89","author":"Hartog-Jager, W.A.; Hanlo, P.W.; Ansink, B.J.J.; Vermeulen, M.B.M.","year":"1987","unstructured":"Hartog-Jager WA, Hanlo PW, Ansink BJJ, Vermeulen MBM. Results of a questionnaire in 100 ALS patients and 100 control cases. Clin Neurol Neurosurg 1987;89:37-41.","journal-title":"Clin Neurol Neurosurg"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1159\/000110782","article-title":"Antecedent events in amyotrophic lateral sclerosis: do they influence clinical onset and progression?","volume":"9","author":"Provinciali, L.; Giovagnoli, A.R.","year":"1990","unstructured":"Provinciali L, Giovagnoli AR. Antecedent events in amyotrophic lateral sclerosis: do they influence clinical onset and progression? Neuroepidemiology 1990;9:255-62.","journal-title":"Neuroepidemiology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1159\/000110267","article-title":"Risk factors in motor neuron disease: a case-control study","volume":"10","author":"Chio, A.; Meineri, P.; Tribolo, A.; Schiffer, D.","year":"1991","unstructured":"Chio A, Meineri P, Tribolo A, Schiffer D. Risk factors in motor neuron disease: a case-control study. Neuroepidemiology 1991;10:174-84.","journal-title":"Neuroepidemiology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1001\/archneur.1976.00500060062015","article-title":"A search for clues to the cause of amyotrophic lateral sclerosis","volume":"33","author":"Hanisch, R.; Dworsky, R.L.; Henderson, B.E.","year":"1976","unstructured":"Hanisch R, Dworsky RL, Henderson BE. A search for clues to the cause of amyotrophic lateral sclerosis. Arch Neurol 1976;33:456-7.","journal-title":"Arch Neurol"},{"key":"ref_16","first-page":"102","article-title":"Repeat study of antecedent events in motor neuron disease","volume":"13","author":"Pierce-Ruhland, R.; Patton, B.M.","year":"1981","unstructured":"Pierce-Ruhland R, Patton BM. Repeat study of antecedent events in motor neuron disease. Anmals of Clinical Research 1981;13:102-7.","journal-title":"Anmals of Clinical Research"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1212\/WNL.34.3.393","article-title":"Amyotrophic lateral sclerosis and heavy metals: A pilot case-control study","volume":"34","author":"Roelofs-Iverson, R.A.; Mulder, D.W.; Elveback, L.R.; Kurland, L.T.; Molgaard, C.A.","year":"1984","unstructured":"Roelofs-Iverson RA, Mulder DW, Elveback LR, Kurland LT, Molgaard CA. Amyotrophic lateral sclerosis and heavy metals: A pilot case-control study Neurology 1984;34:393-5.","journal-title":"Neurology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1093\/oxfordjournals.aje.a114308","article-title":"A case-control study of amyotrophic lateral sclerosis","volume":"123","author":"Deapen, D.M.; Henderson, B.E.","year":"1986","unstructured":"Deapen DM, Henderson BE. A case-control study of amyotrophic lateral sclerosis. Am J Epidemiol 1986;123:790-9.","journal-title":"Am J Epidemiol"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000110810","article-title":"Amyotrophic lateral sclerosis and occupational heavy metal exposure: a case control study","volume":"5","author":"Gresham, L.S.; Molgaard, C.A.; Golbeck, A.L.; Smith, R.","year":"1986","unstructured":"Gresham LS, Molgaard CA, Golbeck AL, Smith R. Amyotrophic lateral sclerosis and occupational heavy metal exposure: a case control study. Neuroepidemiology 1986;5: 29-38.","journal-title":"Neuroepidemiology"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1001\/archneur.1990.00530010046017","article-title":"Amyotrophic lateral sclerosis-a case-control study following detection of a cluster in a small Wisconsin community","volume":"47","author":"Sienko, D.G.; Davis, J.P.; Taylor, J.A.; Brooks, B.R.","year":"1990","unstructured":"Sienko DG, Davis JP, Taylor JA, Brooks BR. Amyotrophic lateral sclerosis-a case-control study following detection of a cluster in a small Wisconsin community. Arch Neurol 1990;47:38-41.","journal-title":"Arch Neurol"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1212\/WNL.26.2.167","article-title":"Antecedent events in amyotrophic lateral sclerosis","volume":"26","author":"Felmus, M.T.; Patten, B.M.; Swanke, L.","year":"1976","unstructured":"Felmus MT, Patten BM, Swanke L. Antecedent events in amyotrophic lateral sclerosis. Neurology 1976;26:167-72.","journal-title":"Neurology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/archneur.1981.00510040046007","article-title":"Case-control studies of motor neuron disease, association with mechanical injuries","volume":"38","author":"Kondo, K.; Tsubaki, T.","year":"1981","unstructured":"Kondo K, Tsubaki T. Case-control studies of motor neuron disease, association with mechanical injuries. Arch Neurol 1981;38:220-6.","journal-title":"Arch Neurol"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1212\/WNL.41.7.1077","article-title":"Epidemiologic correlates of sporadic amyotrophic lateral sclerosis","volume":"41","author":"Armon, C.; Kurland, L.T.; Daube, JR, O.'Brien; P.C.","year":"1991","unstructured":"Armon C, Kurland LT, Daube JR, O'Brien PC. Epidemiologic correlates of sporadic amyotrophic lateral sclerosis. Neurology 1991;41:1077-84.","journal-title":"Neurology"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1212\/WNL.30.5.453","article-title":"Epidemiology of amyotrophic lateral scklrosis: a case-control comparison based on ALS deaths","volume":"30","author":"Kurtzke, J.F.; Beebe, G.W.","year":"1980","unstructured":"Kurtzke JF, Beebe GW. Epidemiology of amyotrophic lateral scklrosis: a case-control comparison based on ALS deaths. Neurology 1980;30:453-62.","journal-title":"Neurology"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1111\/j.1600-0404.1991.tb03970.x","article-title":"Amyotrophic lateral sclerosis in Sweden in relation to occupation","volume":"83","year":"1991","unstructured":"Gunnarsson L-G, Lindberg G, Soderfeldt B, Axelson 0. Amyotrophic lateral sclerosis in Sweden in relation to occupation. Acta Neurol Scand 1991;83:394-8.","journal-title":"Acta Neurol Scand"},{"key":"ref_26","article-title":"Epi Info Version 5. A word processing, database, and statistics program for epidemiology on micro-computers","author":"Dean, A.D.; Dean, J.A.; Burton, A.H.; Dicker, R.C.","year":"1990","unstructured":"Dean AD, Dean JA, Burton AH, Dicker RC. Epi Info Version 5. A word processing, database, and statistics program for epidemiology on micro-computers. Mountain, A: USA Incorporated, 1990."},{"key":"ref_27","article-title":"SYSTA T: the system for statistics","author":"Wilkinson, L.","year":"1989","unstructured":"Wilkinson, L. SYSTA T: the system for statistics. Evanston, IL; Systat Inc, 1989."},{"key":"ref_28","first-page":"63","article-title":"Bengtsson N-0, Axelson 0. Confounding in occupational studies","volume-title":"occupational epidemiology","author":"Fredrikson, M.; Hardell, L.","year":"1988","unstructured":"Fredrikson M, Hardell L, Bengtsson N-0, Axelson 0. Confounding in occupational studies. In: Hogstedt C, Reuterwall C, eds. Progress in occupational epidemiology. Amsterdam: Elsevier Science Publishers, 1988:63-6."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1001\/archneur.1990.00530010050018","article-title":"The mortality of motor neuron disease","volume":"47","year":"1990","unstructured":"Gunnarsson LG, Lindberg G, Soderfeldt B, Axelson 0. The mortality of motor neuron disease in Sweden. Arch Neurol 1990;47:42-6.","journal-title":"in Sweden. Arch Neurol"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1749-6632.1989.tb46653.x","article-title":"TRH and TRH receptors in the spinal cord","volume":"553","author":"Winokur, A.; Manaker, S.; Kreider, M.S.","year":"1989","unstructured":"Winokur A, Manaker S, Kreider MS. TRH and TRH receptors in the spinal cord. Ann NY Acad Sci 1989;553:314-24.","journal-title":"Ann NY Acad Sci"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.49.11.791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T11:20:07Z","timestamp":1601119207000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.49.11.791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,11,1]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1992,11,1]]}},"URL":"https:\/\/doi.org\/10.1136\/oem.49.11.791","relation":{},"ISSN":["1351-0711"],"issn-type":[{"value":"1351-0711","type":"print"}],"subject":[],"published":{"date-parts":[[1992,11,1]]}}}