{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:56:05Z","timestamp":1790934965167,"version":"4.1.0"},"reference-count":11,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1994,9]]},"abstract":"<jats:p>Findings are presented from the initial cross sectional phase of a cohort study of employees exposed to flour in bakeries or mills. Of 401 eligible workers in seven sites 344 (86%) were surveyed; symptoms assessed by self completed questionnaire, and sensitisation measured by the response to skin prick tests, were related to intensity of exposure both to total dust and to flour aeroallergen. Among 264 subjects without previous occupational exposure to flour, work related symptoms which started after first employment at the site were related to exposure intensity, especially when exposure was expressed in terms of flour aeroallergen. The relations with eye\/nose and skin symptoms were independent of atopic status and cigarette smoking. Positive skin test responses to mixed flour and to alpha amylase were also more frequent with increasing exposure intensity, although this was confounded by atopic status. There was only a weak association between symptoms and specific sensitisation.<\/jats:p>","DOI":"10.1136\/oem.51.9.579","type":"journal-article","created":{"date-parts":[[2008,12,17]],"date-time":"2008-12-17T00:14:48Z","timestamp":1229472888000},"page":"579-583","source":"Crossref","is-referenced-by-count":103,"title":["Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to flour."],"prefix":"10.1136","volume":"51","author":[{"given":"P","family":"Cullinan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Lowson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J","family":"Nieuwenhuijsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Sandiford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R D","family":"Tee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K M","family":"Venables","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A J","family":"Newman Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1994,9,1]]},"reference":[{"key":"ref_1","first-page":"292","article-title":"Occupational respiratory disease in the United Kingdom: a report to the British Thoracic Society and the Society of Occupational Medicine by the SWORD project group","volume":"48","author":"Meredith, S.; Taylor, V.; McDonald, J.C.","year":"1991","unstructured":"Meredith S, Taylor V, McDonald JC. Occupational respiratory disease in the United Kingdom: a report to the British Thoracic Society and the Society of Occupational Medicine by the SWORD project group. Br J Ind Med 1991;48:292-8.","journal-title":"Br J Ind Med"},{"key":"ref_2","first-page":"636","article-title":"Respiratory symptoms, lung function, and sensitisation to flour in a British bakery","volume":"46","author":"Musk, A.W.; Venables, K.M.; Crook, B.","year":"1989","unstructured":"Musk AW, Venables KM, Crook B, et al. Respiratory symptoms, lung function, and sensitisation to flour in a British bakery. BrJ Ind Med 1989;46:636-42.","journal-title":"BrJ Ind Med"},{"key":"ref_3","first-page":"55","article-title":"A rabbit antibody assay to measure wheat flour aeroallergen","volume":"47","author":"Sandiford, C.; Tee, R.D.; Newman Taylor, A.J.","year":"1992","unstructured":"Sandiford C, Tee RD, Newman Taylor AJ. A rabbit antibody assay to measure wheat flour aeroallergen. 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Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to laboratory rats. 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