{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:14:17Z","timestamp":1771013657495,"version":"3.50.1"},"reference-count":46,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1995,3]]},"abstract":"<jats:p>OBJECTIVES--To assess airflow limitation in workers exposed long term to metal dust, the prevalence of pleural plaques in those workers exposed in the past to asbestos, the influence of pleural plaques on lung function, and the possible association with airway disease caused by asbestos. METHODS--A cross sectional and longitudinal (seven year) survey of 494 long term (mean (SEM) 21(1) years) workers in a copper refinery was carried out from medical questionnaires, chest radiographs, and forced spirometry. RESULTS--The prevalence of lifetime non-smokers was 19%, current smokers 39%, and ex-smokers 42%. The prevalence of chronic obstructive pulmonary diseases (COPD) (forced expiratory volume in one second (FEV1) &lt; 80% predicted) was 5%, small airway dysfunction (SAD) (maximal mid-expiratory flow (MMEF) &lt; 60% predicted) was 7%, and this did not differ from the control population. The COPD and SAD were associated with cumulative smoking index but not with the cumulative work years at the plant or with any type of work at the plant. The mean (SEM) reduction of FEV1 was 20(7) ml in non-smokers, 26(4) ml in smokers, and 26(5) ml in ex-smokers (P &gt; 0.05). In the smokers and ex-smokers with COPD, the loss of FEV1 was 53(10) (P &lt; 0.02). The prevalence of pleural plaques was 11% (P &lt; 0.0001); pleural plaques were found in older workers with known exposure to asbestos. The pleural plaques were circumscribed and associated with a non-significant 196 ml reduction in forced vital capacity (FVC) and non-significant reduction of FVC over time. The pleural plaques were not associated with COPD or SAD. The cumulative smoking index obtained by a technician did not differ from that by a chest physician. CONCLUSIONS--Despite exposures to asbestos that produced pleural plaques and exposures to metal dusts and foundry fumes the long term workers of this plant did not have excessive prevalence of COPD or SAD. The data suggest that low level long term exposure to metal dusts, gases, and foundry fumes do not necessarily cause respiratory dysfunction, circumscribed pleural plaques with low grades of width and extent do not reduce FVC significantly, and exposure to asbestos dust that produced pleural plaques does not necessarily produce airway dysfunction.<\/jats:p>","DOI":"10.1136\/oem.52.3.204","type":"journal-article","created":{"date-parts":[[2008,12,17]],"date-time":"2008-12-17T00:14:48Z","timestamp":1229472888000},"page":"204-210","source":"Crossref","is-referenced-by-count":14,"title":["Respiratory health of workers exposed to metal dusts and foundry fumes in a copper refinery."],"prefix":"10.1136","volume":"52","author":[{"given":"G","family":"Ostiguy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Vaillancourt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"B\u00e9gin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1995,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1378\/chest.88.4.608","article-title":"Chronic airflow limitation: its relationship to work in dusty occupations","volume":"88","author":"Becklake, M.R.","year":"1985","unstructured":"Becklake MR. 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The natural history of chronic airflow obstruction. BMJ3 1977;1:1645-8."},{"key":"ref_29","first-page":"152","article-title":"Effects of smoking and environmental pollutants","volume-title":"Respiratory function in disease","author":"Bates, D.V.","year":"1989","unstructured":"Bates DV. Effects of smoking and environmental pollutants. In: DV Bates, ed. Respiratory function in disease. Philadelphia: WB Saunders, 1989:152-67."},{"key":"ref_30","first-page":"271","article-title":"Evaluation of studies which have demonstrated pulmonary function changes","volume-title":"Permutt eds. The lung in the transition between health and disease. Vol 12. Lung biology in health and disease","author":"Buist, A.S.; Smoking, Ducic S.","year":"1979","unstructured":"Buist AS, Ducic S. Smoking. Evaluation of studies which have demonstrated pulmonary function changes. In: PT Macklem, S Permutt eds. The lung in the transition between health and disease. Vol 12. Lung biology in health and disease. New York: Marcel Dekker, 1979:271-86."},{"key":"ref_31","article-title":"The natural history of chronic bronchitis and emphysema","author":"Fletcher, C.; Peto, R.; Tinker, C.; Speizer, F.E.","year":"1976","unstructured":"Fletcher C, Peto R, Tinker C, Speizer FE. The natural history of chronic bronchitis and emphysema. Oxford: Oxford University Press, 1976."},{"key":"ref_32","first-page":"31","article-title":"Pulmonary impairment smelter. Am from chronic exposure to sulfur","volume":"116","author":"Smith, T.J.; Peters, J.M.; Reading, J.C.; Castle, C.H.","year":"1977","unstructured":"Smith TJ, Peters JM, Reading JC, Castle CH. Pulmonary impairment smelter. Am from chronic exposure to sulfur Rev RespirDis 1977;116:31-4.","journal-title":"Rev RespirDis"},{"key":"ref_33","first-page":"35","article-title":"Task force on occupational respiratory disease [G Ostiguy, chairman]. Health and welfare Canada","year":"1979","unstructured":"Task force on occupational respiratory disease [G Ostiguy, chairman]. Health and welfare Canada. Ottawa: Canadian Government, 1979:35-48."},{"key":"ref_34","first-page":"689","article-title":"Computed tomography in the early detection of asbestosis","volume":"50","author":"Begin, R.; Ostiguy, G.; Filion, R.; Colman, N.; Bertrand, P.","year":"1993","unstructured":"Begin R, Ostiguy G, Filion R, Colman N, Bertrand P. Computed tomography in the early detection of asbestosis. BrJ Ind Med 1993;50:689-98.","journal-title":"BrJ Ind Med"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/j.1749-6632.1991.tb24490.x","article-title":"Pleural plaques in the general population","volume":"643","author":"Hillerdal, G.","year":"1991","unstructured":"Hillerdal G. Pleural plaques in the general population. 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