{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:37:21Z","timestamp":1787017041712,"version":"build-2736575974"},"reference-count":25,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1996,1]]},"DOI":"10.1136\/oem.53.1.1","type":"journal-article","created":{"date-parts":[[2008,12,16]],"date-time":"2008-12-16T19:14:48Z","timestamp":1229454888000},"page":"1-5","source":"Crossref","is-referenced-by-count":37,"title":["Cancer in relation to occupational exposure to trichloroethylene."],"prefix":"10.1136","volume":"53","author":[{"given":"N S","family":"Weiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1996,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1749-6632.1988.tb30120.x","article-title":"Long-term carcinogenicity bioassays on trichlorethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F, mice","volume":"534","author":"Maltoni, C.; Lefemine, G.; Cotti, G.; Perino, G.","year":"1988","unstructured":"Maltoni C, Lefemine G, Cotti G, Perino G. Long-term carcinogenicity bioassays on trichlorethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F, mice. Ann NYAcad Sci 1988;534:316-42.","journal-title":"Ann NYAcad Sci"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF00366179","article-title":"Carcinogenicity study of trichloroethylene by long-term inhalation in three animal species","volume":"43","author":"Henschler, D.; Romen, W.; Elsasser, H.M.; Reichert, D.; Eder, E.; Radwan, Z.","year":"1980","unstructured":"Henschler D, Romen W, Elsasser HM, Reichert D, Eder E, Radwan Z. Carcinogenicity study of trichloroethylene by long-term inhalation in three animal species. Arch Toxicol 1980;43:237-48.","journal-title":"Arch Toxicol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/BF01032599","article-title":"Carcinogenicity study of trichloroethylene with and without epoxide stabilizers in mice","volume":"104","author":"Henschler, D.; Romen, W.; Eder, E.","year":"1984","unstructured":"Henschler D, Romen W, Eder E. Carcinogenicity study of trichloroethylene with and without epoxide stabilizers in mice. J Cancer Res Clin Oncol 1984;104:149-56.","journal-title":"J Cancer Res Clin Oncol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0041-008X(87)90325-5","article-title":"The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver","volume":"90","author":"Herren-Freund, S.L.; Pereira, M.A.; Khoury, M.D.; Olson, G.","year":"1987","unstructured":"Herren-Freund SL, Pereira MA, Khoury MD, Olson G. The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver. Toxicol Appl Pharmacol 1987;90:183-9.","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.2486\/indhealth.21.243","article-title":"Inhalation carcinogenicity of trichlorethylene in mice and rats","volume":"21","author":"Fukuda, K.; Takemoto, K.; Tsurata, H.","year":"1993","unstructured":"Fukuda K, Takemoto K, Tsurata H. Inhalation carcinogenicity of trichlorethylene in mice and rats. Ind Health 1993;21:243-54.","journal-title":"Ind Health"},{"key":"ref_6","first-page":"531","article-title":"Retrospective cohort mortality study of workers at an aircraft maintenance facility II. Exposures and the assessment","volume":"48","author":"Spirtas, R.; Stewart, P.; Lee, S.","year":"1991","unstructured":"Spirtas R, Stewart P, Lee S. Retrospective cohort mortality study of workers at an aircraft maintenance facility II. Exposures and the assessment. Br J Ind Med 1991;48: 531-7.","journal-title":"Br J Ind Med"},{"key":"ref_7","first-page":"556","article-title":"Updated and expanded Swedish cohort study of trichloroethylene and cancer risk","volume":"36","year":"1994","unstructured":"Axelson 0, Selden A, Andersson K, Hogstedt C. Updated and expanded Swedish cohort study of trichloroethylene and cancer risk. Y Occup Med 1994;36:556-62.","journal-title":"Y Occup Med"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1097\/00043764-199507000-00008","article-title":"Cancer incidence among Finnish workers exposed to halogenated hydrocarbons","volume":"37","author":"Anttila, A.; Pukkala, E.; Sallmen, M.; Hernberg, S.; Hemminki, K.","year":"1995","unstructured":"Anttila A, Pukkala E, Sallmen M, Hernberg S, Hemminki K. Cancer incidence among Finnish workers exposed to halogenated hydrocarbons. Y Occup Med 1995;37:797-806.","journal-title":"Y Occup Med"},{"key":"ref_9","article-title":"Final report: historical prospective mortality study ofHughes Aircraft employees at airforce plant No 44","author":"Wong 0, Morgan R","year":"1990","unstructured":"Wong 0, Morgan R. Final report: historical prospective mortality study ofHughes Aircraft employees at airforce plant No 44. Alameda, CA: ENSR Health Sciences, 1990."},{"key":"ref_10","first-page":"531","article-title":"Retrospective cohort mortality study of workers at an aircraft maintenance facility II. Exposures and their assessment","volume":"48","author":"Stewart, P.A.; Lee, J.S.; Marano, D.E.; Spirtas, R.; Forbes, C.D.; Blair, A.","year":"1991","unstructured":"Stewart PA, Lee JS, Marano DE, Spirtas R, Forbes CD, Blair A. Retrospective cohort mortality study of workers at an aircraft maintenance facility II. Exposures and their assessment. BrJ Ind Med 1991;48:531-7.","journal-title":"BrJ Ind Med"},{"key":"ref_11","first-page":"683","article-title":"Mortality of aircraft manufacturing workers in southern California. Am 3 Ind Med","volume":"13","author":"Garabrant, D.H.; Held, J.; Langhold, B.; Bernstein, L.","year":"1988","unstructured":"Garabrant DH, Held J, Langhold B, Bernstein L. Mortality of aircraft manufacturing workers in southern California. Am 3 Ind Med 1988;13:683-93."},{"key":"ref_12","first-page":"1838","article-title":"Colon cancer, physical activity, and occupational exposures, a case-control study","volume":"63","year":"1989","unstructured":"Fredriksson M, Bengtsson N-O, Hardell L, Axelson 0. Colon cancer, physical activity, and occupational exposures, a case-control study. Cancer 1989;63:1838-42.","journal-title":"Cancer"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1136\/bmj.286.6368.846","article-title":"Incidence of liver cancer and trichloroethylene manufacture: joint study by industry and a cancer registry","volume":"286","author":"Paddle, G.M.","year":"1983","unstructured":"Paddle GM. Incidence of liver cancer and trichloroethylene manufacture: joint study by industry and a cancer registry. BMJ 1983;286:846.","journal-title":"BMJ"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/bjc.1984.188","article-title":"Aetiological aspects on primary liver cancer with special regard to alcohol, organic solvents and acute intermittent porphyria-an epidemiological investigation","volume":"50","author":"Hardell, L.; Bengtsson, N.O.; Jonsson, U.; Eriksson, S.; Larsson, L.G.","year":"1984","unstructured":"Hardell L, Bengtsson NO, Jonsson U, Eriksson S, Larsson LG. Aetiological aspects on primary liver cancer with special regard to alcohol, organic solvents and acute intermittent porphyria-an epidemiological investigation. Br Y Cancer 1984;50:389-97.","journal-title":"Br Y Cancer"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"356","DOI":"10.5271\/sjweh.1907","article-title":"Increased risk for primary liver cancer among women exposed to solvents","volume":"14","author":"Hernberg, S.; Kauppinen, T.; Riala, R.; Korkala, M.L.; Asikainen, U.","year":"1988","unstructured":"Hernberg S, Kauppinen T, Riala R, Korkala ML, Asikainen U. Increased risk for primary liver cancer among women exposed to solvents. Scand J Work Environ Health 1988;14:356-65.","journal-title":"Scand J Work Environ Health"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/bjc.1981.25","article-title":"Malignant lymphoma and exposure to chemicals, especially organic solvents, chlorophenols and phenoxy acids: a case-control study","volume":"43","author":"Hardell, L.; Eriksson, M.; Lenner, P.; Lundgren, E.","year":"1981","unstructured":"Hardell L, Eriksson M, Lenner P, Lundgren E. Malignant lymphoma and exposure to chemicals, especially organic solvents, chlorophenols and phenoxy acids: a case-control study. BrJ Cancer 1981;43:169-76.","journal-title":"BrJ Cancer"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s002040050173","article-title":"Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene","volume":"69","author":"Henschler, D.; Vamvakas, S.; Lammert, M.; Dekant, W.; Kraus, B.; Thomas, B.","year":"1995","unstructured":"Henschler D, Vamvakas S, Lammert M, Dekant W, Kraus B, Thomas B, et al. Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene. Arch Toxicol 1995;69:291-9.","journal-title":"Arch Toxicol"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/00043764-198508000-00015","article-title":"A cohort study of employees of a manufacturing plant using trichloroethylene","volume":"27","author":"Shindell, S.; Ulrich, S.","year":"1985","unstructured":"Shindell S, Ulrich S. A cohort study of employees of a manufacturing plant using trichloroethylene. Y Occup Med 1985;27:577-9.","journal-title":"Y Occup Med"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ajim.4700260203","article-title":"Occupational exposure to chlorinated aliphatic hydrocarbons and risk of astrocytic brain cancer","volume":"26","author":"Heineman, E.F.; Gomez, Cocco P.; MR, Dosemeci; M, Stewart; PA, Haynes; R.B.","year":"1994","unstructured":"Heineman EF, Cocco P. Gomez MR, Dosemeci M, Stewart PA, Haynes RB, et al. Occupational exposure to chlorinated aliphatic hydrocarbons and risk of astrocytic brain cancer. Am J Ind Med 1994;26:155-69.","journal-title":"Am J Ind Med"},{"issue":"2","key":"ref_20","article-title":"Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Hum Exp Toxicol","volume":"13","author":"Ashby, J.; Brady, A.; Elcombe, C.R.; Elliott, B.M.; Ishmael, J.; Odum, J.","year":"1994","unstructured":"Ashby J, Brady A, Elcombe CR, Elliott BM, Ishmael J, Odum J, et al. Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Hum Exp Toxicol 1994;13(suppl 2)."},{"key":"ref_21","first-page":"6","article-title":"Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene. A biochemical human hazard assessment","volume":"8","author":"Elcombe, C.R.","year":"1985","unstructured":"Elcombe CR. Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene. A biochemical human hazard assessment. Arch Toxicol 1985; 8(suppl):6-1 7.","journal-title":"Arch Toxicol"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0009-2797(92)90042-J","article-title":"A mechanism for the development of Clara cell lesions in the mouse lung after exposure to trichloroethylene","volume":"83","author":"Odum, J.; Foster, JR, Green; T.","year":"1992","unstructured":"Odum J, Foster JR, Green T. A mechanism for the development of Clara cell lesions in the mouse lung after exposure to trichloroethylene. Chem Biol Interact 1992;83:135-53.","journal-title":"Chem Biol Interact"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/aja.1001550103","article-title":"The Clara cell: a complete ultrastructural study in mammals","volume":"155","author":"Smith, M.N.; Greenberg, D.S.; Spjut, H.J.","year":"1979","unstructured":"Smith MN, Greenberg DS, Spjut HJ. The Clara cell: a complete ultrastructural study in mammals. Am Anat 1979; 155:15-30.","journal-title":"Am Anat"},{"key":"ref_24","article-title":"American Conference of Governmental Industrial Hygienists. Threshold limit values for chemical substances and physical agents and biological exposure indices","year":"1993","unstructured":"American Conference of Governmental Industrial Hygienists. Threshold limit values for chemical substances and physical agents and biological exposure indices, 1993-4. Cincinnati: ACGIH, 1993."},{"key":"ref_25","article-title":"International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans: preamble. Vol 62. Wood dust andformaldehyde","year":"1995","unstructured":"International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans: preamble. Vol 62. Wood dust andformaldehyde. Geneva: IARC World Health Organization, 1995."}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.53.1.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T10:06:28Z","timestamp":1716458788000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.53.1.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1996,1,1]]},"published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1136\/oem.53.1.1"],"URL":"https:\/\/doi.org\/10.1136\/oem.53.1.1","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}