{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:01:19Z","timestamp":1761058879678},"reference-count":8,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1996,8]]},"abstract":"<jats:p>A 32 year old male research physician accidentally received a minor wound from a needle which had been previously used on rabbit tissue. Within 15 minutes serious anaphylactic reactions started and he was taken to hospital where his condition stabilised within five hours. Serum immunoglobulin E antibodies to rabbit epithelium were high (16.2 U\/ml), although other antibody titres were low. Allergy tests were not carried out before employment, so this alarming scenario could not have been predicted. People with confirmed laboratory animal allergy should be warned of the dangers of continued unprotected exposure and avoidance of the allergen should be encouraged by good laboratory practice and respiratory protective equipment.<\/jats:p>","DOI":"10.1136\/oem.53.8.573","type":"journal-article","created":{"date-parts":[[2008,12,17]],"date-time":"2008-12-17T00:14:48Z","timestamp":1229472888000},"page":"573-574","source":"Crossref","is-referenced-by-count":22,"title":["Laboratory animal allergy: anaphylaxis from a needle injury."],"prefix":"10.1136","volume":"53","author":[{"given":"A D","family":"Watt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C P","family":"McSharry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1996,8,1]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"What you should know about allergy to laboratory animals. Health and Safety Commission","volume":"885527","author":"0","year":"1990","unstructured":"What you should know about allergy to laboratory animals. Health and Safety Commission, HMSO 1990, ISBN 0 11 885527 1."},{"key":"ref_2","first-page":"660","article-title":"Laboratory animal allergy in a pharmaceutical company","volume":"45","author":"Venables, K.M.; Tee, R.D.; Hawkins, E.R.; Gordon, B.J.; Wale, C.J.; Farrer, N.M.","year":"1988","unstructured":"Venables KM, Tee RD, Hawkins ER, Gordon BJ, Wale CJ, Farrer NM, et al. Laboratory animal allergy in a pharmaceutical company. Br _Ind Med 1988;45:660-6.","journal-title":"Br _Ind Med"},{"key":"ref_3","first-page":"603","article-title":"Allergy to rabbits 1. Specificity and non-specificity of RAST and cross-radioimmunoelectrophoresis due to the presence of light chains in rabbit allergenic extracts","volume":"41","author":"Price, J.A.; Longbottom, J.L.","year":"1986","unstructured":"Price JA, Longbottom JL. Allergy to rabbits 1. Specificity and non-specificity of RAST and cross-radioimmunoelectrophoresis due to the presence of light chains in rabbit allergenic extracts. Allergy 1986;41:603-12.","journal-title":"Allergy"},{"key":"ref_4","first-page":"667","article-title":"Smoking, atopy, and laboratory animal allergy","volume":"45","author":"Venables, K.M.; Upton, J.L.; Hawkins, E.R.; Tee, R.D.; Longbottom, J.C.; Newman-Taylor, A.J.","year":"1988","unstructured":"Venables KM, Upton JL, Hawkins ER, Tee RD, Longbottom JC, Newman-Taylor AJ. Smoking, atopy, and laboratory animal allergy. Br J Ind Med 1988;45: 667-71.","journal-title":"Br J Ind Med"},{"key":"ref_5","first-page":"248","article-title":"Committee on the Safety of Medicines. CSM update: disensitising vaccines","volume":"293","year":"1986","unstructured":"Committee on the Safety of Medicines. CSM update: disensitising vaccines. BMJ 1986;293:248-50.","journal-title":"BMJ"},{"key":"ref_6","first-page":"442","article-title":"Allergy to laboratory animals. A retrospective and a prospective study","volume":"40","author":"Davies, G.E.; Thompson, A.V.; Niewola, Z.; Burrows, G.E.; Teesdale, E.C.; Bird, D.J.","year":"1983","unstructured":"Davies GE, Thompson AV, Niewola Z, Burrows GE, Teesdale EC, Bird DJ, et al. Allergy to laboratory animals. A retrospective and a prospective study. Br J Ind Med 1983;40:442-9.","journal-title":"Br J Ind Med"},{"key":"ref_7","first-page":"73","article-title":"Health and safety in animal facilities","volume":"886353","author":"011","year":"1992","unstructured":"Health and safety in animal facilities. London: Health and Safety Commission, HMSO, 1992. (ISBN 011 886353 3). 9 Venables KM. Epidemiology and the prevention of occupational asthma. BrJ Ind Med 1987;44:73-5.","journal-title":"BrJ Ind Med; Venables KM. Epidemiology and the prevention of occupational asthma"},{"key":"ref_8","first-page":"1121","article-title":"Health, employment and financial outcome in workers with occupational asthma","volume":"91","author":"Gannon, P.F.; Weir, D.C.; Robertson, A.S.; Barge, P.S.","year":"1993","unstructured":"Gannon PF, Weir DC, Robertson AS, Barge PS. Health, employment and financial outcome in workers with occupational asthma. Allergy Clin Immunol 1993;91:1121-7.","journal-title":"Allergy Clin Immunol"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.53.8.573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T14:35:09Z","timestamp":1716474909000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.53.8.573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,8]]},"references-count":8,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1996,8,1]]},"published-print":{"date-parts":[[1996,8]]}},"alternative-id":["10.1136\/oem.53.8.573"],"URL":"https:\/\/doi.org\/10.1136\/oem.53.8.573","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,8]]}}}