{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:08:46Z","timestamp":1784686126075,"version":"3.55.0"},"reference-count":28,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p>OBJECTIVES: To estimate the risk of cancer due to occupational exposure to petroleum products in the Swedish transport and refinery industries. METHODS: In a retrospective cohort study the cancer incidence in 4128 men and 191 women, who had worked for at least one year in the petroleum industry, was compared with the incidence in the general population. The job titles and employment times for each person were found in personal files in the industries. The men had on average worked in jobs exposed to petroleum for 11.6 years at the end of the observation period. The cases of cancer were identified by record linkage with the Swedish cancer register. RESULTS: In total there were 146 cases of cancer v 157.6 expected (standardised mortality ratio (SMR) 0.93 90% confidence interval (90% CI) 0.80 to 1.1). Operators at refineries had an increased risk of leukaemia (6 cases v 1.7 expected, 90% CI of relative risk (RR) 1.5 to 7.0). Five of the six cases had started to work at the refineries in the 1950s or later. No other significantly increased risk of cancer was found. Distribution workers had a decreased incidence of lung cancer (no cases, 90% CI of RR 0 to 0.4). CONCLUSIONS: Operators at Swedish refineries had an increased risk of leukaemia. A possible cause is exposure to benzene. There was no increased risk of leukaemia in distribution workers. Distribution workers had a decreased risk of lung cancer.<\/jats:p>","DOI":"10.1136\/oem.54.9.686","type":"journal-article","created":{"date-parts":[[2008,12,17]],"date-time":"2008-12-17T00:14:48Z","timestamp":1229472888000},"page":"686-691","source":"Crossref","is-referenced-by-count":31,"title":["Cancer incidence of workers in the Swedish petroleum industry."],"prefix":"10.1136","volume":"54","author":[{"given":"B","family":"J\u00e4rvholm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Mellblom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Norrman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Nordlinder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1997,9,1]]},"reference":[{"key":"ref_1","first-page":"6","article-title":"Exposure of the general population to gasoline","volume":"101","author":"Alkand, G.","year":"1993","unstructured":"Alkand G. 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Occupational exposures in petroleum refining. Lyon: IARC, 1989;45:81-117."},{"key":"ref_4","first-page":"283","article-title":"Critical review of cancer epidemiology in petroleum industry employees, with a quantitative metaanalyses by cancer site","volume":"15","author":"Wong 0, Raabe GK","year":"1989","unstructured":"Wong 0, Raabe GK. Critical review of cancer epidemiology in petroleum industry employees, with a quantitative metaanalyses by cancer site. AmJInd Med 1989;15:283-310.","journal-title":"AmJInd Med"},{"key":"ref_5","first-page":"561","article-title":"Further follow up of mortality in a United Kingdom oil distribution centre cohort","volume":"5","author":"Rushton, L.","year":"1993","unstructured":"Rushton L. Further follow up of mortality in a United Kingdom oil distribution centre cohort. 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Exposure to benzene at different work places in Sweden","volume":"31","author":"Nordlinder, R.","year":"1987","unstructured":"Nordlinder R, Ramnas 0. Exposure to benzene at different work places in Sweden. Ann Occup Hyg 1987;31:345-55.","journal-title":"Ann Occup Hyg"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0003-4878(95)00053-4","article-title":"Exposure of tanker drivers to gasoline and some of its components","volume":"40","author":"Hakkola, M.; Saarienen, L.","year":"1996","unstructured":"Hakkola M, Saarienen L. Exposure of tanker drivers to gasoline and some of its components. Ann Occup Hyg 1996;40:1-10.","journal-title":"Ann Occup Hyg"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1080\/15298669291359807","article-title":"Health effects of tank cleaners","volume":"53","author":"Lillienberg, L.; Hogstedt, B.; Jarvholm, B.; Nilsson, L.","year":"1992","unstructured":"Lillienberg L, Hogstedt B, Jarvholm B, Nilsson L. 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Pavia, Italy: Foudazione Salvatore Maugeri Editizione. 1995;1:107-20."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1136\/oem.52.6.380","article-title":"Risk of myelogenous leukaemia and multiple myeloma in workers exposed to benzene","volume":"52","author":"0, Wong","year":"1995","unstructured":"Wong 0. Risk of myelogenous leukaemia and multiple myeloma in workers exposed to benzene [letter]. Occup Environ Med 1995;52:380-4.","journal-title":"Occup Environ Med"},{"key":"ref_22","first-page":"357","article-title":"Risk of myelogenous leukaemia and multiple myeloma in workers exposed to benzene","volume":"53","author":"0, Wong","year":"1996","unstructured":"Wong 0. Risk of myelogenous leukaemia and multiple myeloma in workers exposed to benzene [letter]. 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Am J7 Ind Med 1996;29:227-35.","journal-title":"Am J7 Ind Med"},{"key":"ref_25","article-title":"Handling of petrol and petroleum products. Work environment and health in tank truck drivers, tank cleaners, lubrication manufacturing workers, and terminal workers","author":"Wallin, M.; Berggren, M.; Bergstrand, L.","year":"1990","unstructured":"Wallin M, Berggren M, Bergstrand L. Handling of petrol and petroleum products. Work environment and health in tank truck drivers, tank cleaners, lubrication manufacturing workers, and terminal workers. Stockholm: Transporthalsan, 1990. (In Swedish.)"},{"key":"ref_26","first-page":"225","article-title":"Low mortality rates in industrial cohort studies due to selection for work and survival in the industry","volume":"30","author":"Fox, A.J.; Collier, P.F.","year":"1976","unstructured":"Fox AJ, Collier PF. Low mortality rates in industrial cohort studies due to selection for work and survival in the industry. 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