{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T17:48:36Z","timestamp":1717004916453},"reference-count":33,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:p>OBJECTIVES: The role of occupational exposures in hairy cell leukaemia was investigated through a multicentre, hospital based, case-control study. This paper analyses the role of exposure to solvents other than benzene in hairy cell leukaemia. METHODS: The study included 226 male cases and 425 matched controls, exposure to solvents was evaluated by expert case by case review of the detailed data on occupational exposures generated by specific interviews. Also, exposure to solvents was evaluated with an independently constructed job exposure matrix (JEM). RESULTS: No association was found between hairy cell leukaemia and previous employment in a job exposed to solvents (odds ratio (OR) 0.9 95% confidence interval (95% CI) 0.6 to 1.3). ORs for the main occupational tasks exposed to solvents were around 1 and did not increase with the frequency or the duration of the tasks. No specific type of paint or glue was found to be significantly associated with hairy cell leukaemia. No association was found with exposure to solvents, taken as a whole, with either expert assessments or the JEM. No association was found with aromatic, chlorinated, or oxygenated subgroups of solvents. The ORs did not increase with the average intensity of exposure assessed by the experts, with the frequency of use, or with the duration of exposure. Finally, no association was found with non-occupational exposure to solvents. CONCLUSIONS: The study did not show any association between exposure to solvents and hairy cell leukaemia.<\/jats:p>","DOI":"10.1136\/oem.55.1.59","type":"journal-article","created":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:13:30Z","timestamp":1230768810000},"page":"59-64","source":"Crossref","is-referenced-by-count":3,"title":["Occupational exposure to solvents and hairy cell leukaemia."],"prefix":"10.1136","volume":"55","author":[{"given":"J","family":"Clavel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Mandereau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Conso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J C","family":"Limasset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Pourmir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Flandrin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"H\u00e9mon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1998,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1365-2141.1987.tb02310.x","article-title":"Is male predominance in hairy cell leukaemia related to occupational exposure to ionizing radiation, benzene and other solvents?","volume":"67","author":"Flandrin, G.; Collado, S.","year":"1987","unstructured":"Flandrin G, Collado S. Is male predominance in hairy cell leukaemia related to occupational exposure to ionizing radiation, benzene and other solvents? Br J Haematol 1987;67:119\u201320.","journal-title":"Br J Haematol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1093\/aje\/121.5.675","article-title":"A case-control inquiry into the etiology of hairy cell leukemia","volume":"121","author":"Oleske, D.; Golomb, H.M.; Farber, M.D.; Levy, P.S.","year":"1985","unstructured":"Oleske D, Golomb HM, Farber MD, Levy PS. A case-control inquiry into the etiology of hairy cell leukemia. Am J Epidemiol 1985;121:675\u201383.","journal-title":"Am J Epidemiol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1111\/j.1365-2141.1993.tb03213.x","article-title":"Hairy cell leukaemia: descriptive epidemiology and a case-control study","volume":"85","author":"Staines, A.; Cartwright, R.A.","year":"1993","unstructured":"Staines A, Cartwright RA. Hairy cell leukaemia: descriptive epidemiology and a case-control study. Br J Haematol 1993;85:714\u20137.","journal-title":"Br J Haematol"},{"key":"ref_4","first-page":"33","article-title":"Chronic lymphatic leukaemia and engine exhausts, fresh wood and DDT: a case referent study","volume":"45","author":"Flodin, U.; Fredriksson, M.; Persson, B.; Axelson, O.","year":"1988","unstructured":"Flodin U, Fredriksson M, Persson B, Axelson O. Chronic lymphatic leukaemia and engine exhausts, fresh wood and DDT: a case referent study. Br J Ind Med 1988;45:33\u20138.","journal-title":"Br J Ind Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1093\/oxfordjournals.aje.a115442","article-title":"Chronic lymphocytic leukemia in relation to chemical exposures","volume":"130","author":"Malone, K.E.; Koepsell, T.D.; Daling, JR","year":"1989","unstructured":"Malone KE, Koepsell TD, Daling JR, et al. Chronic lymphocytic leukemia in relation to chemical exposures. 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