{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:21:46Z","timestamp":1758709306222},"reference-count":29,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[1999,2]]},"abstract":"<jats:p>OBJECTIVES: To investigate the mortality of workers who had been exposed to asbestos, machining fluids and foundry work in a foundry and heavy engineering plant in the railway rolling stock manufacturing industry in New Zealand. METHODS: Historical cohort study design. RESULTS: For the total workforce of 3522 men employed between 1945 and 1991, follow up was 90% of person-years to 31 December 1991. Significantly increased standardised mortality ratios (SMRs) were found for all causes of death combined (SMR 1.07; 95% confidence interval (95% CI) 1.01 to 1.14), all malignancies (SMR 1.15; 95% CI 1.01 to 1.31), circulatory (SMR 1.16; 95% CI 1.07 to 1.27) and musculoskeletal diseases (SMR 3.06; 95% CI 1.39 to 5.84), all digestive cancers (SMR 1.29; 95% CI 1.04 to 1.59), all respiratory cancers (SMR 1.34; 95% CI 1.08 to 1.65), cancer of the oesophagus (SMR 1.97; 95% CI 1.01 to 3.45), and mesothelioma of the pleura (SMR 6.58; 95% CI 1.24 to 19.49). Three deaths from pleural mesothelioma were recorded, with latency times of 51, 53, and 57 years. There were no dose-response relations between exposure to asbestos, machining fluids or foundry work, or by duration of employment in the plant, and any cause of death. CONCLUSIONS: This study found small increases in risk for several causes of death among foundry and heavy engineering workers; however, these increases were small and the possible effects of smoking and other lifestyle factors could not be excluded. There was evidence of asbestos related disease in those involved in engineering work in the past.<\/jats:p>","DOI":"10.1136\/oem.56.2.134","type":"journal-article","created":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:13:30Z","timestamp":1230768810000},"page":"134-138","source":"Crossref","is-referenced-by-count":15,"title":["Historical cohort study of a New Zealand foundry and heavy engineering plant."],"prefix":"10.1136","volume":"56","author":[{"given":"H M","family":"Firth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Elwood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G P","family":"Herbison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1999,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1136\/bmj.300.6733.1161","article-title":"Follow up of New Zealand participants in British atmospheric nuclear weapons tests in the Pacific","volume":"300","author":"Pearce, N.; Prior, I.; Methven, D.","year":"1990","unstructured":"Pearce N, Prior I, Methven D, et al. Follow up of New Zealand participants in British atmospheric nuclear weapons tests in the Pacific. BMJ 1990;300:1161\u20136.","journal-title":"BMJ"},{"key":"ref_2","first-page":"133","article-title":"International Agency for Research on Cancer. Polynuclear aromatic compunds, Part 3, industrial exposures in aluminium production, coal gasification, coke production, and iron and steel founding","volume":"34","year":"1984","unstructured":"International Agency for Research on Cancer. Polynuclear aromatic compunds, Part 3, industrial exposures in aluminium production, coal gasification, coke production, and iron and steel founding. IARC Monogr Eval Carcinog Risk Chem Humans 1984;34:133\u201390.","journal-title":"IARC Monogr Eval Carcinog Risk Chem Humans"},{"key":"ref_3","first-page":"87","article-title":"International Agency for Research on Cancer. Polynuclear aromatic compounds, Part 2, carbon blacks, mineral oils and some nitroarenes","volume":"33","year":"1984","unstructured":"International Agency for Research on Cancer. Polynuclear aromatic compounds, Part 2, carbon blacks, mineral oils and some nitroarenes. IARC Monogr Eval Carcinog Risk Chem Humans 1984;33:87\u2013168.","journal-title":"IARC Monogr Eval Carcinog Risk Chem Humans"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/ajim.4700220604","article-title":"Mortality studies of machining fluid exposure in the automobile industry I: a standardised mortality ratio analysis","volume":"22","author":"Eisen, E.; Tolbert, P.; Monson, R.","year":"1992","unstructured":"Eisen E, Tolbert P, Monson R, et al. Mortality studies of machining fluid exposure in the automobile industry I: a standardised mortality ratio analysis. Am J Ind Med 1992;22:809\u201324.","journal-title":"Am J Ind Med"},{"key":"ref_5","article-title":"International Agency for Research on Cancer. Overall evaluations of carcinogenicity: an updating of IARC monographs. Vols 1\u201342","year":"1987","unstructured":"International Agency for Research on Cancer. Overall evaluations of carcinogenicity: an updating of IARC monographs. Vols 1\u201342. IARC Monogr Eval Carcinog Risk Chem Humans 1987;(suppl 7).","journal-title":"IARC Monogr Eval Carcinog Risk Chem Humans"},{"key":"ref_6","article-title":"EVects on health of exposure to asbestos","author":"Doll, R.; Peto, J.","year":"1985","unstructured":"Doll R, Peto J. EVects on health of exposure to asbestos. London: Health and Safety Commission, 1985."},{"key":"ref_7","first-page":"87","article-title":"Mineral dusts and fibres","volume-title":"Epidemiology of work related diseases","author":"McDonald, J.C.","year":"1995","unstructured":"McDonald JC. Mineral dusts and fibres. In: McDonald JC, ed. Epidemiology of work related diseases. London: BMJ Publishing Group, 1995:87\u2013116."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5271\/sjweh.2329","article-title":"Mortality among asbestos exposed workers in a railroad workshop","volume":"10","author":"Ohlson, C.; Klaesson, B.; Hogstedt, C.","year":"1984","unstructured":"Ohlson C, Klaesson B, Hogstedt C. Mortality among asbestos exposed workers in a railroad workshop. Scand J Work Environ Health 1984;10:283\u201391.","journal-title":"Scand J Work Environ Health"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/ajim.4700130604","article-title":"Relative risk of mesothelioma among railroad machinists exposed to chrysotile","volume":"13","author":"Mancuso, T.F.","year":"1988","unstructured":"Mancuso TF. Relative risk of mesothelioma among railroad machinists exposed to chrysotile. Am J Ind Med 1988;13: 639\u201357.","journal-title":"Am J Ind Med"},{"key":"ref_10","first-page":"1938","volume":"WHO,","author":"Organization, World Health","unstructured":"World Health Organization. International classification of diseases, 6\u20139th CM revision. Geneva: WHO, 1938\u201379.","journal-title":"International classification of diseases, 6\u20139th CM revision. Geneva"},{"key":"ref_11","article-title":"New Zealand standard classifications of occupations","author":"Department of Statistics","year":"1976","unstructured":"Department of Statistics. New Zealand standard classifications of occupations. Wellington: Department of Statistics, 1976."},{"key":"ref_12","article-title":"Manual for PYRS: cohort study analysis program (version 1.3)","author":"Coleman, M.; Hermon, C.; Douglas, A.","year":"1989","unstructured":"Coleman M, Hermon C, Douglas A. Manual for PYRS: cohort study analysis program (version 1.3). Lyon: IARC, 1989."},{"key":"ref_13","article-title":"Statistical methods in cancer research: the design and analysis of cohort studies","author":"Breslow, N.E.; Day, N.E.","year":"1987","unstructured":"Breslow NE, Day NE. Statistical methods in cancer research: the design and analysis of cohort studies. IARC Sci Publ 1987;82.","journal-title":"IARC Sci Publ"},{"key":"ref_14","article-title":"Research methods in occupational epidemiology","author":"Checkoway, H.; Pearce, N.E.; Crawford-Brown, D.J.","year":"1989","unstructured":"Checkoway H, Pearce NE, Crawford-Brown DJ. Research methods in occupational epidemiology. Oxford: Oxford University Press, 1989."},{"key":"ref_15","first-page":"305","article-title":"Relationship of mortality to measures of environmental asbestos pollution in an asbestos textile factory","volume":"29","author":"Peto, J.; Doll, R.; Hermon, C.","year":"1985","unstructured":"Peto J, Doll R, Hermon C, et al. Relationship of mortality to measures of environmental asbestos pollution in an asbestos textile factory. Ann Occup Hyg 1985;29:305\u201355.","journal-title":"Ann Occup Hyg"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/ajim.4700220402","article-title":"Use of death certificates in epidemiological studies, including occupational hazards: discordance with clinical and autopsy findings","volume":"22","author":"SelikoV, I.J.","year":"1992","unstructured":"SelikoV IJ. Use of death certificates in epidemiological studies, including occupational hazards: discordance with clinical and autopsy findings. Am J Ind Med 1992;22:469\u201380.","journal-title":"Am J Ind Med"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/ajim.4700130604","article-title":"Relative risk of mesothelioma among railroad machinists exposed to chrysotile","volume":"13","author":"Mancuso, T.F.","year":"1988","unstructured":"Mancuso TF. 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Am J Ind Med 1991;20:401\u20139.","journal-title":"Am J Ind Med"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1136\/oem.51.5.316","article-title":"Mortality among a cohort of UK steel foundry workers with special reference to cancers of the stomach and lung, 1946\u201390","volume":"51","author":"Sorahan, T.; Faux, A.; Cooke, M.","year":"1994","unstructured":"Sorahan T, Faux A, Cooke M. Mortality among a cohort of UK steel foundry workers with special reference to cancers of the stomach and lung, 1946\u201390. Occup Environ Med 1994;51:316\u201322.","journal-title":"Occup Environ Med"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1097-0274(199709)32:3<223::AID-AJIM7>3.0.CO;2-Y","article-title":"A cohort mortality study of foundry workers","volume":"32","author":"Hanson, E.S.","year":"1997","unstructured":"Hanson ES. A cohort mortality study of foundry workers. Am J Ind Med 1997;32:223\u201333.","journal-title":"Am J Ind Med"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/00043764-199006000-00010","article-title":"Mortality of iron foundry workers: I. Overall findings","volume":"32","author":"Andjelkovich, D.A.; Mathew, R.M.; Richardson, R.B.","year":"1990","unstructured":"Andjelkovich DA, Mathew RM, Richardson RB, et al. Mortality of iron foundry workers: I. Overall findings. J Occup Med 1990;32:529\u201340.","journal-title":"J Occup Med"},{"key":"ref_23","first-page":"315","article-title":"Cancer morbidity among woodworkers in the US automotive industry","volume":"24","author":"Swanson, G.M.; Belle, S.H.","year":"1982","unstructured":"Swanson GM, Belle SH. Cancer morbidity among woodworkers in the US automotive industry. J Occ Med 1982;24:315\u20139.","journal-title":"J Occ Med"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/00043764-199006000-00011","article-title":"Risk of colorectal cancer among automotive pattern and model makers","volume":"32","author":"Tilley, B.; Johnson, C.; Schultz, L.","year":"1990","unstructured":"Tilley B, Johnson C, Schultz L, et al. Risk of colorectal cancer among automotive pattern and model makers. J Occup Med 1990;32:541\u20136.","journal-title":"J Occup Med"},{"key":"ref_25","first-page":"1025","article-title":"Analysis of cancer mortality patterns among workers exposed to cutting oil mists","volume":"61","author":"Decoufle, P.","year":"1978","unstructured":"Decoufle P. Analysis of cancer mortality patterns among workers exposed to cutting oil mists. J Natl Cancer Inst 1978;61:1025\u201330.","journal-title":"J Natl Cancer Inst"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/00039896.1987.9934360","article-title":"Mortality and cancer morbidity in workers exposed to cutting fluids","volume":"42","author":"Jarvholm, B.; Lavenius, B.","year":"1987","unstructured":"Jarvholm B, Lavenius B. Mortality and cancer morbidity in workers exposed to cutting fluids. Arch Environ Health 1987;42:361\u20136.","journal-title":"Arch Environ Health"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/(SICI)1097-0274(199710)32:4<325::AID-AJIM1>3.0.CO;2-T","article-title":"Work-related asthma and respiratory symptoms among workers exposed to metal-working fluids","volume":"32","author":"Rosenman, K.D.; Reilly, M.J.; Kalinowski, D.","year":"1997","unstructured":"Rosenman KD, Reilly MJ, Kalinowski D. Work-related asthma and respiratory symptoms among workers exposed to metal-working fluids. Am J Ind Med 1997;32:325\u201331.","journal-title":"Am J Ind Med"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/(SICI)1097-0274(199704)31:4<403::AID-AJIM5>3.0.CO;2-W","article-title":"Respiratory symptoms and lung function abnormalities among machine operators in automobile production","volume":"31","author":"Sprince, N.L.; Thorne, P.S.; Popendorf, W.","year":"1997","unstructured":"Sprince NL, Thorne PS, Popendorf W, et al. Respiratory symptoms and lung function abnormalities among machine operators in automobile production. Am J Ind Med 1997;31:403\u201313.","journal-title":"Am J Ind Med"},{"key":"ref_29","first-page":"984","article-title":"Soft tissue sarcomas","volume-title":"epidemiology and prevention","author":"S, Hoar Zahm; MA, Tucker; JF, Fraumeni","year":"1996","unstructured":"Hoar Zahm S, Tucker MA, Fraumeni JF. Soft tissue sarcomas. In: Schottenfeld D, Fraumeni JF, eds. Cancer epidemiology and prevention. Oxford: Oxford University Press, 1996;984\u201399."}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oem.56.2.134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T17:08:05Z","timestamp":1716484085000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oem.56.2.134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2]]},"references-count":29,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1999,2,1]]},"published-print":{"date-parts":[[1999,2]]}},"alternative-id":["10.1136\/oem.56.2.134"],"URL":"https:\/\/doi.org\/10.1136\/oem.56.2.134","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,2]]}}}