{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T20:25:28Z","timestamp":1781382328288,"version":"3.54.1"},"reference-count":46,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1136\/oemed-2013-101555","type":"journal-article","created":{"date-parts":[[2013,10,19]],"date-time":"2013-10-19T01:56:16Z","timestamp":1382147776000},"page":"48-54","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Genes involved in innate immunity associated with asbestos-related fibrotic changes"],"prefix":"10.1136","volume":"71","author":[{"given":"Mari K","family":"Kukkonen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapio","family":"Vehmas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e4ivi","family":"Piiril\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Hirvonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,10,4]]},"reference":[{"key":"key-10.1136\/oemed-2013-101555-1","doi-asserted-by":"crossref","unstructured":"Virta R . Worldwide Asbestos Supply and Consumption Trends from 1900 through 2003. US Geological Survey (Circular 1298). 2006. http:\/\/pubs.usgs.gov\/circ\/2006\/1298\/c1298.pdf","DOI":"10.3133\/cir1298"},{"key":"key-10.1136\/oemed-2013-101555-2","unstructured":"Ban Asbestos Secretariat. http:\/\/ibasecretariat.org"},{"key":"key-10.1136\/oemed-2013-101555-3","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.trsl.2009.01.004","article-title":"Asbestos-induced lung diseases: an update","volume":"153","author":"Kamp","year":"2009","journal-title":"Transl Res"},{"key":"key-10.1136\/oemed-2013-101555-4","unstructured":"World Health Organization. 2010. Asbestos: elimination of asbestos-related diseases. WHO Media Centre. Fact sheet N\u00b0343. http:\/\/www.who.int\/mediacentre\/factsheets\/fs343\/en\/index.html"},{"key":"key-10.1136\/oemed-2013-101555-5","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1002\/ajim.22206","article-title":"Potential years of life lost (PYLL) caused by asbestos-related diseases in the world","volume":"56","author":"Diandini","year":"2013","journal-title":"Am J Ind Med"},{"key":"key-10.1136\/oemed-2013-101555-6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1146\/annurev-pathol-020712-163942","article-title":"Molecular basis of asbestos-induced lung disease","volume":"8","author":"Liu","year":"2013","journal-title":"Annu Rev Pathol"},{"key":"key-10.1136\/oemed-2013-101555-7","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1056\/NEJM198906293202604","article-title":"Asbestos-related diseases","volume":"320","author":"Mossman","year":"1989","journal-title":"N Engl J Med"},{"key":"key-10.1136\/oemed-2013-101555-8","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1590\/S0100-879X2005001000009","article-title":"Role of matrix metalloproteinases in the development of airway inflammation and remodeling","volume":"38","author":"Lagente","year":"2005","journal-title":"Braz J Med Biol Res"},{"key":"key-10.1136\/oemed-2013-101555-9","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1165\/rcmb.2005-0471OC","article-title":"Matrix metalloproteinases promote inflammation and fibrosis in asbestos-induced lung injury in mice","volume":"35","author":"Tan","year":"2006","journal-title":"Am J Respir Cell Mol Biol"},{"key":"key-10.1136\/oemed-2013-101555-10","doi-asserted-by":"crossref","first-page":"4188","DOI":"10.4049\/jimmunol.150.9.4188","article-title":"Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure","volume":"150","author":"Zhang","year":"1993","journal-title":"J Immunol"},{"key":"key-10.1136\/oemed-2013-101555-11","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/15476910802085822","article-title":"The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo","volume":"5","author":"Sullivan","year":"2008","journal-title":"J Immunotoxicol"},{"key":"key-10.1136\/oemed-2013-101555-12","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1378\/chest.125.2.754","article-title":"The role of transforming growth factor beta in lung development and disease","volume":"125","author":"Bartram","year":"2004","journal-title":"Chest"},{"key":"key-10.1136\/oemed-2013-101555-13","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1177\/039463200702000402","article-title":"Long-lasting production of TGF-beta1 by alveolar macrophages exposed to low doses of asbestos without apoptosis","volume":"20","author":"Nishimura","year":"2007","journal-title":"Int J Immunopathol Pharmacol"},{"key":"key-10.1136\/oemed-2013-101555-14","doi-asserted-by":"crossref","first-page":"400","DOI":"10.3109\/1354750X.2010.481365","article-title":"Tumour necrosis factor-alpha gene polymorphisms in asbestos-induced diseases","volume":"15","author":"Helmig","year":"2010","journal-title":"Biomarkers"},{"key":"key-10.1136\/oemed-2013-101555-15","doi-asserted-by":"crossref","first-page":"655","DOI":"10.2310\/JIM.0b013e3181a4f32a","article-title":"Association of transforming growth factor beta1 gene polymorphisms and asbestos-induced fibrosis and tumors","volume":"57","author":"Helmig","year":"2009","journal-title":"J Investig Med"},{"key":"key-10.1136\/oemed-2013-101555-16","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1111\/j.1440-1827.1998.tb03866.x","article-title":"Immunohistochemical and gelatin zymography studies for matrix metalloproteinases in bleomycin-induced pulmonary fibrosis","volume":"48","author":"Yaguchi","year":"1998","journal-title":"Pathol Int"},{"key":"key-10.1136\/oemed-2013-101555-17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0002-9440(10)64529-4","article-title":"The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system","volume":"157","author":"Swaisgood","year":"2000","journal-title":"Am J Pathol"},{"key":"key-10.1136\/oemed-2013-101555-18","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1126\/science.1156995","article-title":"Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica","volume":"320","author":"Dostert","year":"2008","journal-title":"Science"},{"key":"key-10.1136\/oemed-2013-101555-19","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1002\/art.23286","article-title":"Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases?","volume":"58","author":"Verma","year":"2008","journal-title":"Arthritis Rheum"},{"key":"key-10.1136\/oemed-2013-101555-20","doi-asserted-by":"crossref","first-page":"9035","DOI":"10.1073\/pnas.0803933105","article-title":"The Nalp3 inflammasome is essential for the development of silicosis","volume":"105","author":"Cassel","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key-10.1136\/oemed-2013-101555-21","doi-asserted-by":"crossref","first-page":"8539","DOI":"10.1073\/pnas.88.19.8539","article-title":"Vitamin D3 binding protein (group-specific component) is a precursor for the macrophage-activating signal factor from lysophosphatidylcholine-treated lymphocytes","volume":"88","author":"Yamamoto","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key-10.1136\/oemed-2013-101555-22","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1136\/thx.2009.128793","article-title":"The vitamin D axis in the lung: a key role for vitamin D-binding protein","volume":"65","author":"Chishimba","year":"2010","journal-title":"Thorax"},{"key":"key-10.1136\/oemed-2013-101555-23","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/(SICI)1097-0274(199609)30:3<241::AID-AJIM1>3.0.CO;2-1","article-title":"Screening for asbestos-induced diseases in Finland","volume":"30","author":"Koskinen","year":"1996","journal-title":"Am J Ind Med"},{"key":"key-10.1136\/oemed-2013-101555-24","doi-asserted-by":"crossref","first-page":"109","DOI":"10.5271\/sjweh.287","article-title":"Radiographic abnormalities among Finnish construction, shipyard and asbestos industry workers","volume":"24","author":"Koskinen","year":"1998","journal-title":"Scand J Work Environ Health"},{"key":"key-10.1136\/oemed-2013-101555-25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.5271\/sjweh.596","article-title":"High-resolution computed tomography classification of lung fibrosis for patients with asbestos-related disease","volume":"27","author":"Huuskonen","year":"2001","journal-title":"Scand J Work Environ Health"},{"key":"key-10.1136\/oemed-2013-101555-26","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s00420-001-0297-x","article-title":"Computed tomography of asbestos-related pleural abnormalities","volume":"75","author":"Tiitola","year":"2002","journal-title":"Int Arch Occup Environ Health"},{"key":"key-10.1136\/oemed-2013-101555-27","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1183\/09031936.00073606","article-title":"Chest CT screening of asbestos-exposed workers: lung lesions and incidental findings","volume":"29","author":"Vierikko","year":"2007","journal-title":"Eur Respir J"},{"key":"key-10.1136\/oemed-2013-101555-28","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1097\/00043764-200212000-00015","article-title":"Different measures of asbestos exposure in estimating risk of lung cancer and mesothelioma among construction workers","volume":"44","author":"Koskinen","year":"2002","journal-title":"J Occup Environ Med"},{"key":"key-10.1136\/oemed-2013-101555-29","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.2105\/AJPH.93.12.2055","article-title":"Environmental tobacco smoke and adult-onset asthma: a population-based incident case-control study","volume":"93","author":"Jaakkola","year":"2003","journal-title":"Am J Public Health"},{"key":"key-10.1136\/oemed-2013-101555-30","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1183\/09031936.98.11051021","article-title":"Asbestosis, pleural plaques and diffuse pleural thickening: three distinct benign responses to asbestos exposure","volume":"11","author":"Gevenois","year":"1998","journal-title":"Eur Respir J"},{"key":"key-10.1136\/oemed-2013-101555-31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1475-097X.2008.00827.x","article-title":"Association of findings in flow-volume spirometry with high-resolution computed tomography signs in asbestos-exposed male workers","volume":"29","author":"Piiril\u00e4","year":"2009","journal-title":"Clin Physiol Funct Imaging"},{"key":"key-10.1136\/oemed-2013-101555-32","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.radonc.2004.12.012","article-title":"TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer","volume":"75","author":"Andreassen","year":"2005","journal-title":"Radiother Oncol"},{"key":"key-10.1136\/oemed-2013-101555-33","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1093\/hmg\/11.5.569","article-title":"The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function","volume":"11","author":"Joos","year":"2002","journal-title":"Hum Mol Genet"},{"key":"key-10.1136\/oemed-2013-101555-34","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/rheumatology\/41.2.223","article-title":"Tumour necrosis factor alpha G\u2192A -238 and G\u2192A -308 polymorphisms in juvenile idiopathic arthritis","volume":"41","author":"Ozen","year":"2002","journal-title":"Rheumatology"},{"key":"key-10.1136\/oemed-2013-101555-35","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"key-10.1136\/oemed-2013-101555-36","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1086\/379378","article-title":"A comparison of bayesian methods for haplotype reconstruction from population genotype data","volume":"73","author":"Stephens","year":"2003","journal-title":"Am J Hum Genet"},{"key":"key-10.1136\/oemed-2013-101555-37","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2174\/1874312901206010080","article-title":"The role of the NLRP3 inflammasome in fibrosis","volume":"6","author":"Artlett","year":"2012","journal-title":"Open Rheumatol J"},{"key":"key-10.1136\/oemed-2013-101555-38","doi-asserted-by":"crossref","first-page":"L627","DOI":"10.1152\/ajplung.00225.2012","article-title":"The inflammasome in lung diseases","volume":"303","author":"dos Santos","year":"2012","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"key-10.1136\/oemed-2013-101555-39","doi-asserted-by":"crossref","first-page":"e34977","DOI":"10.1371\/journal.pone.0034977","article-title":"The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1beta and IL-18 production","volume":"7","author":"Verma","year":"2012","journal-title":"PLoS One"},{"key":"key-10.1136\/oemed-2013-101555-40","doi-asserted-by":"crossref","first-page":"e47949","DOI":"10.1371\/journal.pone.0047949","article-title":"Polymorphisms in inflammasome genes and risk of coal workers\u2019 pneumoconiosis in a Chinese population","volume":"7","author":"Ji","year":"2012","journal-title":"PLoS One"},{"key":"key-10.1136\/oemed-2013-101555-41","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1097\/JOM.0b013e3181a01ada","article-title":"What component of coal causes coal workers\u2019 pneumoconiosis?","volume":"51","author":"McCunney","year":"2009","journal-title":"J Occup Environ Med"},{"key":"key-10.1136\/oemed-2013-101555-42","first-page":"2610","article-title":"A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer","volume":"63","author":"Dunning","year":"2003","journal-title":"Cancer Res"},{"key":"key-10.1136\/oemed-2013-101555-43","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1161\/01.CIR.101.24.2783","article-title":"Association of a T29\u2192C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese","volume":"101","author":"Yokota","year":"2000","journal-title":"Circulation"},{"key":"key-10.1136\/oemed-2013-101555-44","doi-asserted-by":"crossref","first-page":"D820","DOI":"10.1093\/nar\/gkm904","article-title":"F-SNP: computationally predicted functional SNPs for disease association studies","volume":"36","author":"Lee","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"key-10.1136\/oemed-2013-101555-45","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1161\/CIRCULATIONAHA.106.613281","article-title":"Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis","volume":"113","author":"Johnson","year":"2006","journal-title":"Circulation"},{"key":"key-10.1136\/oemed-2013-101555-46","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00001648-199001000-00010","article-title":"No adjustments are needed for multiple comparisons","volume":"1","author":"Rothman","year":"1990","journal-title":"Epidemiology"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oemed-2013-101555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T12:10:40Z","timestamp":1688559040000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oemed-2013-101555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,4]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,12,6]]},"published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1136\/oemed-2013-101555"],"URL":"https:\/\/doi.org\/10.1136\/oemed-2013-101555","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,4]]}}}