{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:45:41Z","timestamp":1787503541991,"version":"build-2736575974"},"reference-count":33,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Occup Environ Med"],"accepted":{"date-parts":[[2019,6,30]]},"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Previously published studies on parental occupational exposure to extremely low-frequency magnetic fields (ELF-MF) and risk of acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) in their offspring were inconsistent. We therefore evaluated this question within the Childhood Leukemia International Consortium.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We pooled 11 case\u2013control studies including 9723 childhood leukaemia cases and 17\u2009099 controls. Parental occupational ELF-MF exposure was estimated by linking jobs to an ELF-MF job-exposure matrix (JEM). Logistic regression models were used to estimate ORs and 95% CIs in pooled analyses and meta-analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>ORs from pooled analyses for paternal ELF-MF exposure &gt;0.2\u2009microtesla (\u00b5T) at conception were 1.04 (95% CI 0.95 to 1.13) for ALL and 1.06 (95% CI 0.87 to 1.29) for AML, compared with \u22640.2 \u00b5T. Corresponding ORs for maternal ELF-MF exposure during pregnancy were 1.00 (95% CI 0.89 to 1.12) for ALL and 0.85 (95% CI 0.61 to 1.16) for AML. No trends of increasing ORs with increasing exposure level were evident. Furthermore, no associations were observed in the meta-analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this large international dataset applying a comprehensive quantitative JEM, we did not find any associations between parental occupational ELF-MF exposure and childhood leukaemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/oemed-2019-105706","type":"journal-article","created":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T17:19:25Z","timestamp":1564420765000},"page":"746-753","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Parental occupational exposure to low-frequency magnetic fields and risk of leukaemia in the offspring: findings from the Childhood Leukaemia International Consortium (CLIC)"],"prefix":"10.1136","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6548-358X","authenticated-orcid":false,"given":"Madar","family":"Talibov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Olsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Erdmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Metayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Magnani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Petridou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anssi","family":"Auvinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Logan","family":"Spector","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Clavel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eve","family":"Roman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Dockerty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atte","family":"Nikkil\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olli","family":"Lohi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodora","family":"Psaltopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Miligi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Cardis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Sch\u00fcz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,7,29]]},"reference":[{"key":"2024110804300862000_76.10.746.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(17)30186-9"},{"key":"2024110804300862000_76.10.746.2","unstructured":"World Health Organization. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon, France: International Agency for Research on Cancer, 2008."},{"key":"2024110804300862000_76.10.746.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2014.09.013"},{"key":"2024110804300862000_76.10.746.4","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.arcmed.2016.11.017","article-title":"Environmental exposure and risk of childhood leukemia: an overview","volume":"47","author":"Sch\u00fcz","year":"2016","journal-title":"Arch Med Res"},{"key":"2024110804300862000_76.10.746.5","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24225"},{"key":"2024110804300862000_76.10.746.6","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp117"},{"key":"2024110804300862000_76.10.746.7","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1007\/s10654-018-0402-z","article-title":"Advanced parental age as risk factor for childhood acute lymphoblastic leukemia: results from studies of the Childhood Leukemia International Consortium","volume":"33","author":"Petridou","year":"2018","journal-title":"Eur J Epidemiol"},{"key":"2024110804300862000_76.10.746.8","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1816"},{"key":"2024110804300862000_76.10.746.9","doi-asserted-by":"crossref","unstructured":"Savage SA , Sch\u00fcz J . Environmental chemicals and childhood cancer. Nriagu JO , ed. Encyclopedia of environmental health. Burlington: Elsevier, 2011:336\u201346.","DOI":"10.1016\/B978-0-444-52272-6.00017-9"},{"key":"2024110804300862000_76.10.746.10","doi-asserted-by":"publisher","DOI":"10.1016\/0890-6238(92)90190-5"},{"key":"2024110804300862000_76.10.746.11","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2000.1376"},{"key":"2024110804300862000_76.10.746.12","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-200011000-00003"},{"key":"2024110804300862000_76.10.746.13","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605838"},{"key":"2024110804300862000_76.10.746.14","unstructured":"International Agency for Research on Cancer. Non-Ionizing Radiation, Part 1: Static and Extremely Low-Frequency (ELF) Electric and Magnetic Fields. Lyon, France: International Agency for Research on Cancer, 2002."},{"key":"2024110804300862000_76.10.746.15","unstructured":"World Health Organization. Environmental health criteria; 238. extremely low frequency fields. World Health Organization; 2007. 2016 https:\/\/www.who.int\/peh-emf\/publications\/elf_ehc\/en\/ (Accessed 12 Sep 2018)."},{"key":"2024110804300862000_76.10.746.16","unstructured":"Scientific Committee on Emerging and Newly Identified Health Risks. Potential health effects of exposure to electromagnetic fields (EMF): Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR), 2015."},{"key":"2024110804300862000_76.10.746.17","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008922016813"},{"key":"2024110804300862000_76.10.746.18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19991210)83:6<718::AID-IJC3>3.0.CO;2-T"},{"key":"2024110804300862000_76.10.746.19","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21021"},{"key":"2024110804300862000_76.10.746.20","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/01.ede.0000078421.60231.bc","article-title":"Maternal occupational exposure to extremely low frequency magnetic fields during pregnancy and childhood leukemia","volume":"14","author":"Infante-Rivard","year":"2003","journal-title":"Epidemiology"},{"key":"2024110804300862000_76.10.746.21","doi-asserted-by":"publisher","DOI":"10.1136\/oem.60.12.901"},{"key":"2024110804300862000_76.10.746.22","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp339"},{"key":"2024110804300862000_76.10.746.23","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.365"},{"key":"2024110804300862000_76.10.746.24","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.canep.2012.12.011","article-title":"The Childhood Leukemia International Consortium","volume":"37","author":"Metayer","year":"2013","journal-title":"Cancer Epidemiol"},{"key":"2024110804300862000_76.10.746.25","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1002\/ijc.30264","article-title":"Background radiation and childhood leukemia: A nationwide register-based case-control study","volume":"139","author":"Nikkil\u00e4","year":"2016","journal-title":"Int J Cancer"},{"key":"2024110804300862000_76.10.746.26","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28854"},{"key":"2024110804300862000_76.10.746.27","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-14-0102"},{"key":"2024110804300862000_76.10.746.28","doi-asserted-by":"publisher","DOI":"10.1080\/15459620701528001"},{"key":"2024110804300862000_76.10.746.29","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"2024110804300862000_76.10.746.30","unstructured":"Rothman KJ GS , Lash TL . Modern epidemiology. 3rd ed. Philadelphia: Wolters Kluwer Health\/Lippincott Williams & Wilkins, 2008."},{"key":"2024110804300862000_76.10.746.31","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1093\/oxfordjournals.aje.a116500","article-title":"Effect of nondifferential misclassification on estimates of odds ratios with multiple levels of exposure","volume":"136","author":"Birkett","year":"1992","journal-title":"Am J Epidemiol"},{"key":"2024110804300862000_76.10.746.32","doi-asserted-by":"crossref","unstructured":"Siemiatycki JRL , Boffetta P . Occupation. Schottenfeld DFJ , ed. Cancer epidemiology and prevention. 3rd ed. New-York: Oxford University Press, 2006:322\u201354.","DOI":"10.1093\/acprof:oso\/9780195149616.003.0018"},{"key":"2024110804300862000_76.10.746.33","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.19.1.35"}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oemed-2019-105706","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T07:31:13Z","timestamp":1731051073000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oemed-2019-105706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,29]]},"references-count":33,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,9,12]]},"published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1136\/oemed-2019-105706"],"URL":"https:\/\/doi.org\/10.1136\/oemed-2019-105706","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,29]]}}}