{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T01:10:41Z","timestamp":1793322641907,"version":"4.5.0"},"reference-count":39,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Occup Environ Med"],"accepted":{"date-parts":[[2019,10,28]]},"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Previous analyses of cataract in radiation-exposed populations have assessed relative risk; radiogenic excess additive risk (EAR), arguably of more public health importance, has not been estimated. Previous analysis of a large prospective cohort of US radiologic technologists (USRT) quantified excess relative risk of cataract in relation to occupational radiation dose. We aim to assess EARs of cataract.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We estimated EARs of cataract\/cataract surgery in the USRT cohort using generalised additive models in relation to occupational radiation exposure, and assessed risk modification by a priori-selected cataract risk factors (diabetes, body mass index, smoking, race, sex, birth-year, ultraviolet B (UVB) radiation exposure).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 11\u2009345 cataract diagnoses and 5440 of cataract surgery during 832\u2009462 and 888\u2009402 person-years of follow-up, respectively. Cumulative occupational radiation exposure was associated with self-reported cataract, but not with cataract surgery, with EAR\/10<jats:sup>4<\/jats:sup>person-year Gy=94 (95% CI: 47 to 143, p&lt;0.001) and EAR\/10<jats:sup>4<\/jats:sup>person-year Gy=13 (95% CI: &lt;0 to 57, p=0.551), respectively. There was marked (p&lt;0.001) variation of EAR by age and by diabetes status, with risk higher among persons \u226575 years and diabetics. There were indications of elevated risk among those with higher UVB radiation (p=0.045), whites (p=0.056) and among those with higher levels of cigarette smoking (p=0.062). Elevated additive risk was observed for estimated occupational radiation eye-lens doses &lt;100\u2009mGy (p=0.004) with no dose\u2013response curvature (p=0.903).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The elevated additive risks associated with low-dose radiation, if confirmed elsewhere, have important public health and clinical implications for radiation workers as well as regulatory measures.<\/jats:p><\/jats:sec>","DOI":"10.1136\/oemed-2019-105902","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T22:19:23Z","timestamp":1575325163000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":48,"title":["Occupational radiation exposure and excess additive risk of cataract incidence in a cohort of US radiologic 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