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The results were used to calculate attributable deaths and disability-adjusted life years (DALYs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were an estimated 349\u2009000 (95% Uncertainty Interval 269\u2009000 to 427\u2009000) deaths and 7.2 (5.8 to 8.6)\u2009million DALYs in 2016 due to exposure to the included occupational carcinogens\u20143.9% (3.2% to 4.6%) of all cancer deaths and 3.4% (2.7% to 4.0%) of all cancer DALYs; 79% of deaths were of males and 88% were of people aged 55 \u201379 years. Lung cancer accounted for 86% of the deaths, mesothelioma for 7.9% and laryngeal cancer for 2.1%. Asbestos was responsible for the largest number of deaths due to occupational carcinogens (63%); other important risk factors were secondhand smoke (14%), silica (14%) and diesel engine exhaust (5%). The highest mortality rates were in high-income regions, largely due to asbestos-related cancers, whereas in other regions cancer deaths from secondhand smoke, silica and diesel engine exhaust were more prominent. From 1990 to 2016, there was a decrease in the rate for deaths (\u221210%) and DALYs (\u221215%) due to exposure to occupational carcinogens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Work-related carcinogens are responsible for considerable disease burden worldwide. The results provide guidance for prevention and control initiatives.<\/jats:p><\/jats:sec>","DOI":"10.1136\/oemed-2019-106012","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T14:25:16Z","timestamp":1581603916000},"page":"151-159","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":103,"title":["Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016"],"prefix":"10.1136","volume":"77","author":[{"name":"GBD 2016 Occupational Carcinogens Collaborators","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"key":"2020050723155227000_77.3.151.1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20209"},{"key":"2020050723155227000_77.3.151.2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.605"},{"key":"2020050723155227000_77.3.151.3","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1038\/bjc.2012.112","article-title":"Occupational cancer burden in Great Britain","volume":"107(Suppl 1)","author":"Rushton","year":"2012","journal-title":"Br J Cancer"},{"key":"2020050723155227000_77.3.151.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61766-8"},{"key":"2020050723155227000_77.3.151.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00128-2"},{"key":"2020050723155227000_77.3.151.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31679-8"},{"key":"2020050723155227000_77.3.151.7"},{"key":"2020050723155227000_77.3.151.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32225-6"},{"key":"2020050723155227000_77.3.151.9","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2019-106008"},{"key":"2020050723155227000_77.3.151.10","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2019-106013"},{"key":"2020050723155227000_77.3.151.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31833-0"},{"key":"2020050723155227000_77.3.151.12"},{"key":"2020050723155227000_77.3.151.13","unstructured":"Institute for Health Metrics and Evaluation . 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