{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:07:12Z","timestamp":1767168432372,"version":"build-2238731810"},"reference-count":12,"publisher":"BMJ","issue":"2","funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["ARADyAL (RD16\/0006\/0014)"],"award-info":[{"award-number":["ARADyAL (RD16\/0006\/0014)"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["ARADyAL (RD16\/0006\/0024)"],"award-info":[{"award-number":["ARADyAL (RD16\/0006\/0024)"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI17\/00615"],"award-info":[{"award-number":["PI17\/00615"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"FEDER for the Thematic Networks and Co-operative Research Centres"},{"DOI":"10.13039\/501100003339","name":"Consejo Superior de Investigaciones Cient\u00edficas","doi-asserted-by":"publisher","award":["SAF2017-86483-R"],"award-info":[{"award-number":["SAF2017-86483-R"]}],"id":[{"id":"10.13039\/501100003339","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Occup Environ Med"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      Several studies have described peach tree (PT) as an occupational allergen. The aim of this work was to assess the effect of\n                      <jats:italic>Prunus persica<\/jats:italic>\n                      9 (Pru p 9), a recently identified allergen from PT pollen, in exposed workers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included people who reported respiratory symptoms after handling PT in orchards during the flowering period (Blanca village, Murcia region, south-east Spain). After completing a detailed questionnaire, participants underwent skin prick test (SPT) and nasal provocation test (NPT). The IgE response was analysed by SDS-PAGE and immunoblotting assays.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 21 cases were included (mean age 45 years; 57% women). Most were polysensitised to common pollens, although one person was sensitised only to PT pollen. All cases had a positive SPT to this pollen, and 43% also to Pru p 9. All participants reported having rhinitis, and six participants reported having also asthma. Immunoblotting showed a heterogeneous IgE pattern for several proteins, with Pru p 9 recognised in nine cases. Most participants sensitised to PT pollen and Pru p 9 had positive NPTs, while those who were not sensitised to Pru p 9 tested negative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We demonstrate for the first time that Pru p 9, an allergen from PT pollen, can induce respiratory symptoms following occupational exposure. This must be considered a relevant allergen when people working with PT cultivars develop respiratory symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/oemed-2020-106641","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T17:21:48Z","timestamp":1602868908000},"page":"142-144","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["<i>Prunus persica<\/i>\n                    9, a new occupational allergen from peach tree pollen involved in rhinitis and asthma"],"prefix":"10.1136","volume":"78","author":[{"given":"Laura","family":"Victorio-Puche","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0141-8914","authenticated-orcid":false,"given":"Maria Luisa","family":"Somoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Martin-Pedraza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Fernandez-Caldas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Abel Fernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirian","family":"Moran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Luis","family":"Subiza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Damian","family":"Lopez-Sanchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayte","family":"Villalba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Blanca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,10,16]]},"reference":[{"key":"2021020103450936000_78.2.142.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/pai.12563","article-title":"EAACI molecular allergology user's guide","volume":"27","author":"Matricardi","year":"2016","journal-title":"Pediatr Allergy Immunol"},{"key":"2021020103450936000_78.2.142.2","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1365-2222.2004.01871.x","article-title":"Respiratory allergy to peach leaves and lipid-transfer proteins","volume":"34","author":"Garc\u00eda","year":"2004","journal-title":"Clin Exp Allergy"},{"key":"2021020103450936000_78.2.142.3","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1111\/all.13163","article-title":"Occupational respiratory allergy in peach crop workers","volume":"72","author":"P\u00e9rez-Calder\u00f3n","year":"2017","journal-title":"Allergy"},{"key":"2021020103450936000_78.2.142.4","doi-asserted-by":"crossref","unstructured":"Victorio-Puche L , L\u00f3pez-S\u00e1nchez D , Blanca-Lopez N , et al . Peach pollen sensitisation is highly prevalent in areas of great extension of peach tree cultivar. J Allergy Clin Immunol 2018;141:AB31. doi:10.1016\/j.jaci.2017.12.099","DOI":"10.1016\/j.jaci.2017.12.099"},{"key":"2021020103450936000_78.2.142.5","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/pai.13067","article-title":"Peach tree pollen and Pru P 9 may induce rhinoconjunctivitis and asthma in children","volume":"30","author":"Somoza","year":"2019","journal-title":"Pediatr Allergy Immunol"},{"key":"2021020103450936000_78.2.142.6","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1159\/000502352","article-title":"Peach tree pollen and Prunus persica 9 sensitisation and allergy in children and adolescents","volume":"180","author":"Victorio Puche","year":"2019","journal-title":"Int Arch Allergy Immunol"},{"key":"2021020103450936000_78.2.142.7","unstructured":"Allergome . A platform for allergen knowledge. Available: http:\/\/www.allergome.org"},{"key":"2021020103450936000_78.2.142.8","article-title":"Pru P 9, a new allergen eliciting respiratory symptoms in subjects sensitized to peach tree pollen","volume":"15","author":"Blanca","year":"2020","journal-title":"PLoS One"},{"key":"2021020103450936000_78.2.142.9","doi-asserted-by":"publisher","DOI":"10.1186\/2045-7022-3-3"},{"key":"2021020103450936000_78.2.142.10","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1002\/mnfr.201500782","article-title":"Two nonspecific lipid transfer proteins (nsLTPs) from tomato seeds are associated to severe symptoms of tomato-allergic patients","volume":"60","author":"Mart\u00edn-Pedraza","year":"2016","journal-title":"Mol Nutr Food Res"},{"key":"2021020103450936000_78.2.142.11","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1111\/all.13416","article-title":"EAACI position paper on the standardization of nasal allergen challenges","volume":"73","author":"Aug\u00e9","year":"2018","journal-title":"Allergy"},{"key":"2021020103450936000_78.2.142.12","first-page":"483","article-title":"Occupational allergy to peach (Prunus persica)tree pollen and potential cross-reactivity between rosaceae family pollens","volume":"14","author":"Jiang","year":"2015","journal-title":"Iran J Allergy Asthma Immunol"}],"updated-by":[{"DOI":"10.1136\/oemed-2020-106641corr1","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000}}],"container-title":["Occupational and Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/oemed-2020-106641","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T13:11:19Z","timestamp":1669209079000},"score":1,"resource":{"primary":{"URL":"https:\/\/oem.bmj.com\/lookup\/doi\/10.1136\/oemed-2020-106641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,16]]},"references-count":12,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,1]]},"published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1136\/oemed-2020-106641"],"URL":"https:\/\/doi.org\/10.1136\/oemed-2020-106641","relation":{},"ISSN":["1351-0711","1470-7926"],"issn-type":[{"value":"1351-0711","type":"print"},{"value":"1470-7926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,16]]}}}