{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T18:55:31Z","timestamp":1792263331621,"version":"4.4.0"},"reference-count":40,"publisher":"BMJ","issue":"10","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"unspecified","delay-in-days":47,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007707","name":"Istituto Nazionale per l\u2019Assicurazione Contro Gli Infortuni sul Lavoro","doi-asserted-by":"publisher","award":["BRiC ID66\/2022"],"award-info":[{"award-number":["BRiC ID66\/2022"]}],"id":[{"id":"10.13039\/501100007707","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011541","name":"Division of Cancer Epidemiology and Genetics","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/100011541","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Occup Environ Med"],"accepted":{"date-parts":[[2025,11,3]]},"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Using a case\u2013control design, we examined the association between occupational asbestos exposure and risk of peritoneal mesothelioma in the general population in Italy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From the National Mesothelioma Registry, we selected cases (2000\u20132021) with life-time occupational history. Controls were 3045 from three case\u2013control studies (region-sex-age-matched, performed in six regions), one in 2002\u20132004 (2116 population controls) and two in 2012\u20132016 (718 population and 211 hospital controls). For all subjects, exposure assignment was based on a quantitative job-exposure matrix (SYN-JEM). Qualitative expert-based evaluation was available for all cases, but only in 2012\u20132016 for 929 controls. We estimated ORs and 90% CIs using logistic regression models adjusted for residence, gender, period and age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In complete analyses (1591 cases, all years\/regions), the OR for ever exposure was 3.66 (CI 3.21 to 4.18, 45.4% cases and 27.8% controls exposed). Among the exposed, median cumulative exposure (fibres\/mL-years) was 1.4 (max 20.0) in cases and 1.1 (max 10.9) in controls. The OR was 1.55 (1.48 to 1.62) per log\n                      <jats:sub>10<\/jats:sub>\n                      -transformed cumulative exposure. In analyses restricted to 290 cases (same years\/regions of controls), ORs were 3.35 (2.57 to 4.37, 43.8% cases exposed) for ever exposure and 1.52 (1.39 to 1.65) for cumulative exposure. ORs for ever asbestos exposure using expert-based evaluation were particularly high, 4.32 (3.50 to 5.34, 53.9% cases and 26.4% controls exposed) in complete analyses (778 cases) and 6.35 (4.58 to 8.81, 57.1% cases exposed) in restricted analyses (245 cases), but are known to be more prone to bias.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Peritoneal mesothelioma showed clear associations with asbestos exposure using different exposure assessment methods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/oemed-2025-110414","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T18:20:32Z","timestamp":1763403632000},"page":"495-503","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Peritoneal mesothelioma and asbestos exposure: a population-based case\u2013control study in Italy, 2000\u20132021"],"prefix":"10.1136","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8935-3843","authenticated-orcid":false,"given":"Dario","family":"Consonni","sequence":"first","affiliation":[{"name":"Occupational Health Unit, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrica","family":"Migliore","sequence":"additional","affiliation":[{"name":"COR Piemonte, Cancer Epidemiology Unit, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Gangemi","sequence":"additional","affiliation":[{"name":"COR Piemonte, Cancer Epidemiology Unit, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenica","family":"Cavone","sequence":"additional","affiliation":[{"name":"COR Puglia, Section of Occupational Medicine \u201cB. Ramazzini\u201d, Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4072-2871","authenticated-orcid":false,"given":"Luigi","family":"Vimercati","sequence":"additional","affiliation":[{"name":"COR Puglia, Section of Occupational Medicine \u201cB. Ramazzini\u201d, Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Piro","sequence":"additional","affiliation":[{"name":"COR Toscana, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Giovannetti","sequence":"additional","affiliation":[{"name":"COR Toscana, Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Zabeo","sequence":"additional","affiliation":[{"name":"COR Veneto, Azienda Zero, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Comiati","sequence":"additional","affiliation":[{"name":"COR Veneto, Azienda Zero, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4343-8873","authenticated-orcid":false,"given":"Stefania","family":"Curti","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9639-7430","authenticated-orcid":false,"given":"Stefano","family":"Mattioli","sequence":"additional","affiliation":[{"name":"Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Teresa","family":"Landi","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute Division of Cancer Epidemiology and Genetics, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmela","family":"Gioscia","sequence":"additional","affiliation":[{"name":"COR Valle d\u2019Aosta, Local Health Authority of Valle d\u2019Aosta, Aosta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Eccher","sequence":"additional","affiliation":[{"name":"COR Province of Trento, Provincial Unit of Health, Hygiene and Occupational Medicine, Trento, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Murano","sequence":"additional","affiliation":[{"name":"COR Province of Bolzano, Alto Adige Health Local Unit, Bolzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"D\u2019Agostin","sequence":"additional","affiliation":[{"name":"COR Friuli-Venezia Giulia, University of Trieste - 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