{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T16:55:55Z","timestamp":1782579355402,"version":"3.54.5"},"reference-count":25,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2014,8,4]]},"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This paper describes the methodology for a prospective, community-based study of sudden unexpected death in Wake County, North Carolina.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>From 1 March to 29 June 2013, data of presumed cardiac arrest cases were captured from Wake County Emergency Medical Services. Participants were screened into the presumed sudden unexpected death group based on specific and sequential screening criteria, and medical and public records were collected for each participant in this group. A committee of independent cardiologists reviewed all data to determine final inclusion\/exclusion of each participant into registry.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We received 398 presumed cardiac arrest referrals. Of these, 105 participants, age 18\u201365\u2005years old, were identified as presumed sudden unexpected deaths. The primary reason for exclusion was survival to hospital (38%). Ninety-five per cent of participants in the presumed sudden unexpected death group experienced an unwitnessed death. Hypertension was present in almost 50%, while dyslipidaemia and diabetes mellitus were present in almost 25% of the same group. In addition, the presumed sudden unexpected death group includes 67.6% males (95% CI 58 to 76) whereas the control group only included 58.9% (95% CI 46 to 55) males.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Participant identification and data collection processes identify presumed sudden unexpected death cases and secure medical and public data for screening and final adjudication. The study infrastructure developed in Wake County will allow its expansion to other counties in North Carolina. Preliminary data indicate the study presently focuses on a population demographically representative of North Carolina.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/openhrt-2014-000150","type":"journal-article","created":{"date-parts":[[2014,8,28]],"date-time":"2014-08-28T02:17:17Z","timestamp":1409192237000},"page":"e000150","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["Sudden Unexpected Death in North Carolina (SUDDEN): methodology review and screening results"],"prefix":"10.1136","volume":"1","author":[{"given":"Parin P","family":"Nanavati","sequence":"first","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Paul","family":"Mounsey","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irion W","family":"Pursell","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Ross J","family":"Simpson","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Elizabeth","family":"Lewis","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil D","family":"Mehta","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jefferson G","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Emergency Medical Services, Wake County, Raleigh, North Carolina, USA"},{"name":"UNC Department of Emergency Medicine, UNC-CH, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W","family":"Bachman","sequence":"additional","affiliation":[{"name":"Department of Emergency Medical Services, Wake County, Raleigh, North Carolina, USA"},{"name":"UNC Department of Emergency Medicine, UNC-CH, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Brent","family":"Myers","sequence":"additional","affiliation":[{"name":"Department of Emergency Medical Services, Wake County, Raleigh, North Carolina, USA"},{"name":"UNC Department of Emergency Medicine, UNC-CH, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene H","family":"Chung","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiac Electrophysiology, Department of Medicine, UNC Heart and Vascular, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,8,27]]},"reference":[{"key":"2025081711002152000_1.1.e000150.1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.974170"},{"key":"2025081711002152000_1.1.e000150.2","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2010.3"},{"key":"2025081711002152000_1.1.e000150.3","doi-asserted-by":"publisher","DOI":"10.1161\/hc4301.098254"},{"key":"2025081711002152000_1.1.e000150.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.09.064"},{"key":"2025081711002152000_1.1.e000150.5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.023838"},{"key":"2025081711002152000_1.1.e000150.6","first-page":"5","article-title":"Sudden cardiac death","volume":"726","author":"Zaijia","year":"1985","journal-title":"World Health Organ Tech Rep"},{"key":"2025081711002152000_1.1.e000150.7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2002.00709.x"},{"key":"2025081711002152000_1.1.e000150.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(97)70035-8"},{"key":"2025081711002152000_1.1.e000150.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00240-9"},{"key":"2025081711002152000_1.1.e000150.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2008.06.003"},{"key":"2025081711002152000_1.1.e000150.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00355-0"},{"key":"2025081711002152000_1.1.e000150.12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.15.1978"},{"key":"2025081711002152000_1.1.e000150.13","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.6.649"},{"key":"2025081711002152000_1.1.e000150.14","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.2.155"},{"key":"2025081711002152000_1.1.e000150.15","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-008-9095-9"},{"key":"2025081711002152000_1.1.e000150.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2003.11.029"},{"key":"2025081711002152000_1.1.e000150.17","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S1052-3057(96)80027-9","article-title":"The stroke belt consortium","volume":"6","author":"Alberts","year":"1996","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"2025081711002152000_1.1.e000150.18","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.7.1153"},{"key":"2025081711002152000_1.1.e000150.19","unstructured":"U.S. Census Bureau State & County Quickfacts. http:\/\/quickfacts.census.gov (accessed Apr 2014)."},{"key":"2025081711002152000_1.1.e000150.20","unstructured":"Finzi A Manfredini R Montanari P . Management of sudden cardiac death survivors. Heartweb 1998;4\u20138."},{"key":"2025081711002152000_1.1.e000150.21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035087"},{"key":"2025081711002152000_1.1.e000150.22","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.003961"},{"key":"2025081711002152000_1.1.e000150.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.029"},{"key":"2025081711002152000_1.1.e000150.24","unstructured":"National Center for Health Statistics. Worktable 23R Death rates by 10-year age groups: United States and each state, 2007. http:\/\/www.cdc.gov\/nchs\/data\/dvs\/MortFinal2007_Worktable23r.pdf (accessed Apr 2014)."},{"key":"2025081711002152000_1.1.e000150.25","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.976092"}],"container-title":["Open Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/openhrt-2014-000150","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,17]],"date-time":"2025-08-17T18:00:27Z","timestamp":1755453627000},"score":1,"resource":{"primary":{"URL":"https:\/\/openheart.bmj.com\/lookup\/doi\/10.1136\/openhrt-2014-000150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,8,27]]},"published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1136\/openhrt-2014-000150"],"URL":"https:\/\/doi.org\/10.1136\/openhrt-2014-000150","relation":{},"ISSN":["2053-3624"],"issn-type":[{"value":"2053-3624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}