{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T10:28:32Z","timestamp":1793356112992,"version":"4.5.0"},"reference-count":61,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2016,7,19]]},"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To update the Cochrane review comparing the effects of home-based and supervised centre-based cardiac rehabilitation (CR) on mortality and morbidity, quality of life, and modifiable cardiac risk factors in patients with heart disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis. The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, PsycINFO and CINAHL were searched up to October 2014, without language restriction. Randomised trials comparing home-based and centre-based CR programmes in adults with myocardial infarction, angina, heart failure or who had undergone coronary revascularisation were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>17 studies with 2172 patients were included. No difference was seen between home-based and centre-based CR in terms of: mortality (relative risk (RR) 0.79, 95% CI 0.43 to 1.47); cardiac events; exercise capacity (mean difference (MD) \u22120.10, \u22120.29 to 0.08); total cholesterol (MD 0.07\u2005mmol\/L, \u22120.24 to 0.11); low-density lipoprotein cholesterol (MD \u22120.06\u2005mmol\/L, \u22120.27 to 0.15); triglycerides (MD \u22120.16\u2005mmol\/L, \u22120.38 to 0.07); systolic blood pressure (MD 0.2\u2005mm\u2005Hg, \u22123.4 to 3.8); smoking (RR 0.98, 0.79 to 1.21); health-related quality of life and healthcare costs. Lower high-density lipoprotein cholesterol (MD \u22120.07\u2005mmol\/L, \u22120.11 to \u22120.03, p=0.001) and lower diastolic blood pressure (MD \u22121.9\u2005mm\u2005Hg, \u22120.8 to \u22123.0, p=0.009) were observed in centre-based participants. Home-based CR was associated with slightly higher adherence (RR 1.04, 95% CI 1.01 to 1.07).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Home-based and centre-based CR provide similar benefits in terms of clinical and health-related quality of life outcomes at equivalent cost for those with heart failure and following myocardial infarction and revascularisation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/openhrt-2016-000463","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T22:49:11Z","timestamp":1473893351000},"page":"e000463","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":137,"title":["Home-based versus centre-based cardiac rehabilitation: abridged Cochrane systematic review and meta-analysis"],"prefix":"10.1136","volume":"3","author":[{"given":"S A","family":"Buckingham","sequence":"first","affiliation":[{"name":"Department of Research, Development & Innovation, Royal Cornwall, Hospitals NHS Trust, Truro, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R S","family":"Taylor","sequence":"additional","affiliation":[{"name":"Institute of Health Research (Primary Care), University of Exeter Medical School, Exeter, Devon, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Jolly","sequence":"additional","affiliation":[{"name":"Institute for Applied Health Research, University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Zawada","sequence":"additional","affiliation":[{"name":"Agency for Health Technology Assessment and Tariff System, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S G","family":"Dean","sequence":"additional","affiliation":[{"name":"Institute of Health Research (Primary Care), University of Exeter Medical School, Exeter, Devon, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cowie","sequence":"additional","affiliation":[{"name":"Cardiac Rehabilitation, University Hospital Ayr, Ayr, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R J","family":"Norton","sequence":"additional","affiliation":[{"name":"Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H M","family":"Dalal","sequence":"additional","affiliation":[{"name":"Department of Research, Development & Innovation, Royal Cornwall, Hospitals NHS Trust, Truro, UK"},{"name":"Institute of Health Research (Primary Care), University of Exeter Medical School, Exeter, Devon, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,9,14]]},"reference":[{"key":"2025081710365739000_3.2.e000463.1","unstructured":"World Health Organization (WHO) 2015. 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